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From FDA reports: side effects of Diphenhydramine for a Male patient aged 62

This is a personalized study for a 62 year old male patient. The study is created by eHealthMe based on reports of 34,946 people who take the same drug and have side effectsfrom FDA.

On Jan, 27, 2015: 34,946 people who reported to have side effects when taking Diphenhydramine are studied

Trend of Diphenhydramine's drug interactions, side effects, and effectiveness reports (3019987)

Information of the patient in this study:

Age: 62

Gender: male

Conditions: Antiallergic Therapy

Drugs taking:
- Diphenhydramine: used for < 1 month

Side effects have: Delirium

eHealthMe real world results:

Comparison with this patient's adverse outcomes among males aged 62 (±5):

Side effectNumber of reports
Delirium (wild excitement)50 (2.05%)

Most common side effects experienced by males aged 62 (±5) in the use of Diphenhydramine:

Side effectNumber of reports
Dyspnoea (difficult or laboured respiration)474
Hypotension (abnormally low blood pressure)422
Pyrexia (fever)362
Fatigue (feeling of tiredness)312
Nausea (feeling of having an urge to vomit)311
Chest Pain244
Pruritus (severe itching of the skin)226

Most common side effects experienced by males aged 62 (±5) in long term use of Diphenhydramine:

Side effectNumber of reports
Injury Nos2
Memory Impairment2
Sexual Dysfunction Nos2
Tinnitus (a ringing in the ears)2
Renal Insufficiency (insufficient excretion of wastes by the kidneys)2
Hypertension Nos2
Disturbance In Attention2
Depression Nos2
Dizziness (excl Vertigo)2

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

Side effectNumber of reports
Delirium (wild excitement)322 (0.92%)

Most common side effects experienced by people in the use of Diphenhydramine:

Side effectNumber of reports
Dyspnoea (difficult or laboured respiration)6,334
Nausea (feeling of having an urge to vomit)5,956
Pyrexia (fever)4,592
Fatigue (feeling of tiredness)4,287
Chest Pain3,788
Headache (pain in head)3,715
Pruritus (severe itching of the skin)3,527

Most common side effects experienced by people in long term use of Diphenhydramine:

Side effectNumber of reports
Headache (pain in head)18
Hypoaesthesia (reduced sense of touch or sensation)18
Haemorrhage (bleeding)16
Gastrooesophageal Reflux Disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)16
Fatigue (feeling of tiredness)15
Insomnia (sleeplessness)14
Loss Of Consciousness14
Weight Decreased14

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Comments from related studies:

  • From this study (1 week ago):

  • Today is the fifth day with no food and water. Had to go into er because I can't hold anything down. The taste on my tongue is as if I'm chewing money or batteries very very annoying. Water seems to boil in my Mouth as soon as it touches my tongue. Forced water and spent My night throwing up all evening. ER gave me Zofran for the nausea. Does absolutely nothing for the taste. Absolutely miserable.


  • From this study (1 month ago):

  • Burning in the vagina and cloudy white discharge.


  • From this study (2 months ago):

  • I took benadryl for hives and soon after, not only did it NOT get rid of the hives but I lost my taste buds. I can't tolerate the taste of food. There IS NO taste.


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Alternative drugs:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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