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From FDA reports: side effects of Diphenhydramine for a Male patient aged 62

This is a personalized study for a 62 year old male patient. The study is created by eHealthMe based on reports of 34,946 people who take the same drug and have side effectsfrom FDA.

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On Jun, 20, 2014: 34,946 people who reported to have side effects when taking Diphenhydramine are studied

Trend of Diphenhydramine's drug interactions, side effects, and effectiveness reports (3019987)

Information of the patient in this study:

Age: 62

Gender: male

Conditions: Antiallergic Therapy

Drugs taking:
- Diphenhydramine: used for < 1 month

Side effects have: Delirium

eHealthMe real world results:

Comparison with this patient's adverse outcomes among males aged 62 (±5):

Side effectNumber of reports
Delirium (wild excitement)50 (2.05%)

Most common side effects experienced by males aged 62 (±5) in the use of Diphenhydramine:

Side effectNumber of reports
Dyspnoea (difficult or laboured respiration)680
Pyrexia (fever)543
Hypotension (abnormally low blood pressure)422
Pruritus (severe itching of the skin)337
Fatigue (feeling of tiredness)312
Nausea (feeling of having an urge to vomit)311
Chest Pain244

Most common side effects experienced by males aged 62 (±5) in long term use of Diphenhydramine:

Side effectNumber of reports
Memory Impairment3
Injury Nos2
Sexual Dysfunction Nos2
Tinnitus (a ringing in the ears)2
Renal Insufficiency (insufficient excretion of wastes by the kidneys)2
Hypertension Nos2
Disturbance In Attention2
Depression Nos2
Dizziness (excl Vertigo)2

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

Side effectNumber of reports
Delirium (wild excitement)322 (0.92%)

Most common side effects experienced by people in the use of Diphenhydramine:

Side effectNumber of reports
Dyspnoea (difficult or laboured respiration)9,138
Pyrexia (fever)6,877
Nausea (feeling of having an urge to vomit)5,956
Pruritus (severe itching of the skin)5,267
Fatigue (feeling of tiredness)4,287
Chest Pain3,788
Headache (pain in head)3,715

Most common side effects experienced by people in long term use of Diphenhydramine:

Side effectNumber of reports
Headache (pain in head)18
Hypoaesthesia (reduced sense of touch or sensation)18
Haemorrhage (bleeding)16
Gastrooesophageal Reflux Disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)16
Fatigue (feeling of tiredness)15
Insomnia (sleeplessness)14
Loss Of Consciousness14
Weight Decreased14

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Comments from related studies:

  • From this study (2 weeks ago):

  • I am taking an over the counter sleep aid made by boots chemist and have got dryes can the tablets b the reason


  • From this study (2 weeks ago):

  • For about four months I am often awakened with tachycardia. No other symptoms. I am able to go back to sleep almost immediately. I have just discontinued Advil pm caplet 1 to see if symptom goes away


  • From this study (2 weeks ago):

  • BP ranges 125-130 over 75-87 when getting up prior to meds to 90-50 sometimes in the evening. I am a little stressed and so diphenhydramine helps me sleep along with melatonin. THese are OTC


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More questions for: Antiallergic Therapy, Delirium

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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