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From FDA reports: drug interactions between Enbrel, Methotrexate for a Female patient aged 60

This is a personalized study for a 60 year old female patient. The study is created by eHealthMe based on reports of 35,618 people who take the same drugs and have drug interactionsfrom FDA.

On Nov, 20, 2014: 35,618 people who reported to have interactions when taking Enbrel, Methotrexate are studied

Trend of Enbrel, Methotrexate's drug interactions, side effects, and effectiveness reports (2856612)

Information of the patient in this study:

Age: 60

Gender: female

Conditions: Rheumatoid Arthritis

Drugs taking:
- Enbrel
- Methotrexate

Drug interactions have: Neuropathy Peripheral

eHealthMe real world results:

Comparison with this patient's adverse outcomes among females aged 60 (±5):

InteractionNumber of reports
Neuropathy Peripheral (surface nerve damage)20 (0.36%)

Most common interactions experienced by females aged 60 (±5) in the use of Enbrel, Methotrexate:

InteractionNumber of reports
Injection Site Pain1,204
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints)946
Injection Site Erythema (redness at injection site)762
Arthralgia (joint pain)660
Injection Site Reaction Nos650
Injection Site Haematoma (localized swelling filled with blood at injection site)550
Injection Site Haemorrhage (bleeding from injection site)540
Drug Ineffective464
Nausea (feeling of having an urge to vomit)440
Cough436

Most common interactions experienced by females aged 60 (±5) in long term use of Enbrel, Methotrexate:

InteractionNumber of reports
Asthenia (weakness)38
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints)26
Oedema Peripheral (superficial swelling)24
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)23
Pneumonia23
Headache (pain in head)21
Fall20
Chills (felling of cold)20
Condition Aggravated (worse condition)20
Cerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)16

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
Neuropathy Peripheral (surface nerve damage)96 (0.27%)

Most common interactions experienced by people in the use of Enbrel, Methotrexate:

InteractionNumber of reports
Injection Site Pain8,434
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints)5,535
Injection Site Erythema (redness at injection site)4,842
Arthralgia (joint pain)3,626
Drug Ineffective2,882
Headache (pain in head)2,800
Injection Site Swelling2,666
Injection Site Pruritus (severe itching at injection site)2,652
Nausea (feeling of having an urge to vomit)2,556
Injection Site Haematoma (localized swelling filled with blood at injection site)2,534

Most common interactions experienced by people in long term use of Enbrel, Methotrexate:

InteractionNumber of reports
Pneumonia227
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints)204
Condition Aggravated (worse condition)178
Pyrexia (fever)162
Drug Ineffective134
Asthenia (weakness)128
Arthralgia (joint pain)110
Weight Decreased104
Dyspnoea (difficult or laboured respiration)95
Nausea (feeling of having an urge to vomit)88

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Comments from related studies:

  • From this study (2 months ago):

  • I have had insomnia off and on all my life until I turned 40 and the I was diagnosed with Psoriatic Arthritis and I was tired all the time and I was sleeping a lot for me and it was good to be able to sleep. The doctor put me on Methotrexate and Enbrel and I could still sleep not as much as before I started the drugs but better than before when I was younger. I went on and off the Enbrel and Methotrexate over the years. I took Adipex for about six months this year for weight loss and that is when I started taking Benadryl to sleep, after I stopped the Adipex and started the Enbrel again my insomnia is worse, I take 2 Benadryl and a 0.5 Xanax every night to sleep and most nights I still don't get to sleep before 1am and many nights even later, I get up at 7am everyday no mater what time I get to sleep and most of the time I am not tired when I wake up, it just really bothers me not being able to sleep when everyone else does.

    Reply

  • From this study (6 months ago):

  • I recently quit taking all meds due to loss of insurance coverage. I have been having symptoms for a week that seem to only get worse

    Reply

  • From this study (6 months ago):

  • Started Enbrel on Friday! Last two days I have very bad eye inflammation and blurry vision with headaches. Could this be a reaction to Enbrel?

    Reply

Post a new comment    OR    Read more comments

Can you answer these questions (Ask a question):

  • Does humira cause excessive sweating?
    Having psoriaticarthritis,fibromyalgia,psoriais,restless leg syndrome,roseacea and high blood pressure means complex health issues and a complex list of medication to go with it. Iam suffering extreme sweating,flushing and now a tickled cough. Now it could be due to going through the change (menopause) but that started a year ago and although I was getting the flushes and sweating,it was nothing like it is now! To me,it seems the excessive sweating started roughly a month after taking Humira. Having so many health issues I'm in tune with any changes and note and monitor them. I started Humira 10 months ago now. My Psoriasis has cleared completely so I'm really pleased. Usually,there's a trade off and you end up with something else! Could the issues I have be down to a single drug on the list,or a combination?
  • Would the tinnitus abate with if i discontinue methotrexate?
    I've just begun my 4th year of Methotrexate for Rheumatoid issue, but it also alleviated my psoriasis. I am hesitant to discontinue because the benefits are great. However, the tinnitus is becoming unbearable and almost maddening. I will more likely consider talking to my doctor about changing medications if 1. The tinnitus subsides with the discontinuance of Methotrexate and if 2. Other rheumatoid medication would not have the same issues with tinnitus. Just discovered the possible connection minutes ago and am eager and hopeful. Please help. Thank you. -Celeste
  • I take klonopin and diltiazem (calcium channel blocker blood pressure medicine) and am concerned about side effects. my accupuncturist recommends the ashwagandha. anyone have any issues with this?
    I take these prescription medications but have been going to an accupuncturist since 2012. I have trouble sleeping at night without my clonazepam and take naps during the day and am having trouble losing weight. She thinks that my adrenal glands may be fatigued and told me to try something called Adrenal Response which contains Sensoril Ashwagandha. When I looked up Ashwaganda it said that it could interact with the Clonazepam or Klonopin and also with High blood pressure medication. I am a little concerned. I mentioned this to her and she said they both are metabolized by the liver and it should be ok to take it, just to take it an hour or more after I take the Clonazepam. Has anyone had any issues with interactions with their prescribed meds while taking Ashwagandha? I don't want to have to monitor my blood pressure because my blood pressure medication works good for me. Any help would be appreciated because I want to try it but I am a little scared too. Thanks, Crystal

More questions for: Enbrel, Methotrexate, Neuropathy Peripheral, Rheumatoid Arthritis

You may be interested at these reviews (Write a review):

  • Hair loss with enbrel
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    I have been on Etanercept for 8 years for Psoriasis. Previous to this I was on
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    This Drug has been my saving grace.
  • Why has my bloodpresher now shot up
    My blood pressure was always low 120/68 now since being treated for rheumatoid arthritis it has shot up to 175/92

More reviews for: Enbrel, Methotrexate, Neuropathy Peripheral, Rheumatoid Arthritis

Complete side effects:

In-depth study of side effects (who have it, when it happens and how):

Could it be a symptom from a condition:

Drug effectiveness in real world:

Alternative drugs:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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