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Related topic: Enbrel, Methotrexate, Neuropathy Peripheral, Rheumatoid Arthritis

From FDA reports: drug interactions between Enbrel, Methotrexate for a Female patient aged 60

This is a personalized study of Enbrel, Methotrexate drug interactions for a 60 year old female patient. The study is created by eHealthMe based on 34,993 people who take the drugs and have drug interactions.

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Information of the patient in this study:

Age: 60

Gender: female

Conditions: Rheumatoid Arthritis

Drugs taking:
- Enbrel
- Methotrexate

Drug interactions have: Neuropathy Peripheral

On Jan, 31, 2014: 34,993 people who reported to have interactions when taking Enbrel, Methotrexate are studied

Trend of Enbrel, Methotrexate's drug interactions, side effects, and effectiveness reports (2856612)

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
Neuropathy Peripheral (surface nerve damage)9 (0.16%)

Most common interactions experienced by females aged 60 (±5) in the use of Enbrel, Methotrexate:

InteractionNumber of reports
Arthralgia (joint pain)634
Injection Site Pain586
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints)467
Injection Site Erythema (redness at injection site)371
Injection Site Reaction Nos367
Injection Site Haematoma (localized swelling filled with blood at injection site)269
Injection Site Haemorrhage (bleeding from injection site)268
Cough217
Nausea (feeling of having an urge to vomit)216
Drug Ineffective215

Most common interactions experienced by females aged 60 (±5) in long term use of Enbrel, Methotrexate:

InteractionNumber of reports
Asthenia (weakness)28
Cerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)16
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints)15
Breast Cancer13
Sepsis (a severe blood infection that can lead to organ failure and death)11
Fall10
Condition Aggravated (worse condition)10
Gastrointestinal Carcinoma (cancer of stomach or intestine)8
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)7
Oedema Peripheral (superficial swelling)7

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
Neuropathy Peripheral (surface nerve damage)46 (0.13%)

Most common interactions experienced by people in the use of Enbrel, Methotrexate:

InteractionNumber of reports
Injection Site Pain4,158
Arthralgia (joint pain)3,522
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints)2,733
Injection Site Erythema (redness at injection site)2,371
Drug Ineffective1,389
Injection Site Swelling1,308
Injection Site Pruritus (severe itching at injection site)1,298
Nausea (feeling of having an urge to vomit)1,257
Injection Site Haematoma (localized swelling filled with blood at injection site)1,252
Injection Site Haemorrhage (bleeding from injection site)1,188

Most common interactions experienced by people in long term use of Enbrel, Methotrexate:

InteractionNumber of reports
Pyrexia (fever)162
Pneumonia127
Asthenia (weakness)113
Arthralgia (joint pain)108
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints)106
Condition Aggravated (worse condition)88
Drug Ineffective67
Weight Decreased52
Lymphoma (cancer that begins in immune system cells)49
Nausea (feeling of having an urge to vomit)44

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