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From FDA reports: drug interactions between Enbrel, Methotrexate for a Female patient aged 60

This is a personalized study for a 60 year old female patient. The study is created by eHealthMe based on reports of 35,618 people who take the same drugs and have drug interactionsfrom FDA.

On Aug, 22, 2014: 35,618 people who reported to have interactions when taking Enbrel, Methotrexate are studied

Trend of Enbrel, Methotrexate's drug interactions, side effects, and effectiveness reports (2856612)

Information of the patient in this study:

Age: 60

Gender: female

Conditions: Rheumatoid Arthritis

Drugs taking:
- Enbrel
- Methotrexate

Drug interactions have: Neuropathy Peripheral

eHealthMe real world results:

Comparison with this patient's adverse outcomes among females aged 60 (±5):

InteractionNumber of reports
Neuropathy Peripheral (surface nerve damage)20 (0.36%)

Most common interactions experienced by females aged 60 (±5) in the use of Enbrel, Methotrexate:

InteractionNumber of reports
Injection Site Pain1,204
Arthralgia (joint pain)990
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints)946
Injection Site Erythema (redness at injection site)762
Injection Site Reaction Nos650
Injection Site Haematoma (localized swelling filled with blood at injection site)550
Injection Site Haemorrhage (bleeding from injection site)540
Drug Ineffective464
Nausea (feeling of having an urge to vomit)440
Cough436

Most common interactions experienced by females aged 60 (±5) in long term use of Enbrel, Methotrexate:

InteractionNumber of reports
Asthenia (weakness)56
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints)26
Cerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)24
Oedema Peripheral (superficial swelling)24
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)23
Pneumonia23
Headache (pain in head)21
Fall20
Condition Aggravated (worse condition)20
Chills (felling of cold)20

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
Neuropathy Peripheral (surface nerve damage)96 (0.27%)

Most common interactions experienced by people in the use of Enbrel, Methotrexate:

InteractionNumber of reports
Injection Site Pain8,434
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints)5,535
Arthralgia (joint pain)5,435
Injection Site Erythema (redness at injection site)4,842
Drug Ineffective2,882
Headache (pain in head)2,800
Injection Site Swelling2,666
Injection Site Pruritus (severe itching at injection site)2,652
Nausea (feeling of having an urge to vomit)2,556
Injection Site Haematoma (localized swelling filled with blood at injection site)2,534

Most common interactions experienced by people in long term use of Enbrel, Methotrexate:

InteractionNumber of reports
Pyrexia (fever)243
Pneumonia227
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints)204
Asthenia (weakness)181
Condition Aggravated (worse condition)178
Arthralgia (joint pain)165
Dyspnoea (difficult or laboured respiration)140
Drug Ineffective134
Weight Decreased104
Nausea (feeling of having an urge to vomit)88

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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