Drug interactions between Gabapentin, Baclofen, Tramadol Hydrochloride for a Female patient aged 61
This is a personalized study of Gabapentin, Baclofen, Tramadol Hydrochloride drug interactions for a 61 year old female patient who has Back Pain - Low. The study is created by eHealthMe based on 259 reports from FDA.
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What are the drugs
Gabapentin has active ingredients of gabapentin. It is used in neuralgia, pain, fibromyalgia, peripheral neuropathy, neuropathy peripheral, neuropathic pain.
Baclofen has active ingredients of baclofen. It is used in muscle spasms, multiple sclerosis, spasticity, back pain - low, pain, muscle spasticity.
Tramadol hydrochloride has active ingredients of tramadol hydrochloride. It is used in pain, back pain - low, fibromyalgia, arthritis, pain in extremity, pain in limb.
On Apr, 13, 2013: 259 people who reported to have interactions when taking Gabapentin, Baclofen, Tramadol Hydrochloride are studied

Information of the patient in this study:
Age: 57
Gender: female
Conditions: Back Pain - Low
Drugs taking:
- Gabapentin - 300MG (gabapentin): used for 1 - 6 months
- Baclofen - 10MG (baclofen): used for 1 - 6 months
- Tramadol Hydrochloride - 50MG (tramadol hydrochloride): used for 1 - 6 months
eHealthMe real world results:
For females aged 57 (±5):
Most common interactions experienced by females aged 57 (±5) in the use of Gabapentin, Baclofen, Tramadol Hydrochloride:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Vomiting | 18 |
| 2 | Hypertension | 16 |
| 3 | Diarrhoea | 14 |
| 4 | Hypokalaemia | 12 |
| 5 | Urinary Tract Infection | 9 |
| 6 | Dehydration | 7 |
| 7 | Rib Fracture | 6 |
| 8 | Hypotension | 6 |
| 9 | Hypoalbuminaemia | 6 |
| 10 | Osteoporosis | 6 |
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Most common interactions experienced by females aged 57 (±5) in long term use of Gabapentin, Baclofen, Tramadol Hydrochloride:
(click on each outcome to view in-depth analysis, incl. how people recovered)| None. |
For people in general (regardless of gender or age):
Most common interactions experienced by people in the use of Gabapentin, Baclofen, Tramadol Hydrochloride:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Anxiety | 65 |
| 2 | Vomiting | 62 |
| 3 | Fatigue | 44 |
| 4 | Pain | 41 |
| 5 | Fall | 40 |
| 6 | Headache | 37 |
| 7 | Dizziness | 33 |
| 8 | Nausea | 32 |
| 9 | Insomnia | 31 |
| 10 | Depression | 29 |
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Most common interactions experienced by people in long term use of Gabapentin, Baclofen, Tramadol Hydrochloride:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Alcohol Use | 3 |
| 2 | Alcoholism | 2 |
| 3 | Drug Ineffective | 2 |
| 4 | Suicidal Ideation | 2 |
| 5 | Depression | 2 |
| 6 | Suicide Attempt | 2 |
| 7 | Intentional Overdose | 1 |
| 8 | Alcohol Poisoning | 1 |
| 9 | Aspiration | 1 |
| 10 | Overdose | 1 |
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Related studies:
- Tramadol Hydrochloride and Gabapentin drug interactions (4,716 reports)
- Tramadol Hydrochloride and Baclofen drug interactions (827 reports)
- Baclofen and Gabapentin drug interactions (3,993 reports)
Drug effectiveness in real world:
- Gabapentin for Back Pain - Low reported by 48 people (updated 2 months ago)
- Baclofen for Back Pain - Low reported by 20 people (updated 1 month ago)
- Tramadol Hydrochloride for Back Pain - Low reported by 158 people (updated 4 weeks ago)
Side effects in real world:
Browse all Gabapentin side effects: 7,386 in total
Browse all Baclofen side effects: 6,351 in total
Browse all Tramadol hydrochloride side effects: 3,080 in total
Browse all Gabapentin side effects: 7,386 in total
Browse all Baclofen side effects: 6,351 in total
Browse all Tramadol hydrochloride side effects: 3,080 in total
Alternative drugs:
- Back Pain - Low (113 drugs) (updated 2 days ago)
Comments from related studies:
From this study (3 weeks ago):
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I have had leg cramps during the night for a number of years. I started taking Gabapentin January 2013 1 capsule evening then increased to 1 capsule in the morning and one at night. March 28, 2013, reduced to 1 capsule at night for one week and then discontinued. Since then I have had severe leg cramps at night. Sometimes waking up every hour all night long. The pharmacist said that I stopped the medication too soon. During that time I had problems with phlegm. I started taking Allegra. The leg cramps continued and I thought it was the Allegra, so I stopped taking that. I have always had low potassium and I had a blood sample taken today. I will have the results tomorrow, but wondered if any of these medications could cause the leg cramps. They are really very severe. I drink water during the day and have been eating a banana every day for the potassium.
There are bound to be more, but I can't think of everything! I honestly wish this would all just go away.
doc moc on Apr, 25, 2013:
see if you can taste poop? its strong so tastebud receptors should fire and cause neural activty if not try celery
doc moc on Apr, 25, 2013:
I think if you just pushed as hard as you could some poops would fall out. If not try drinking 2 litre of milk followed by 500g prune bits. This will sofly relax your poops so they can fall out easily and unselfconsciously.
Please help if you are able.
Background: Very Healthy, active 115 lb. 70 year old female. Worked out, lifted weights, 40 minute walk, 40 deep knee bends, 20 push ups, all daily activities until 8 months ago when became profoundly fatigued, with severe (incapacitating) muscle pain, literally overnight. Had to quit job, as too fatigued to work. Currently: No muscle pain. Debilitating fatigue persists.
Current Meds:
200 Tramadol daily, Chronic Severe Bursitis
8 mgs. Prednisone daily, fatigue
50 mcs. Synthroid daily, Hypothyroidism
300 mgs. Gabapentin daily, Post Herpetic Neuralgia (Shingles)
Savella Dose pack prescribed. Details below.
Current Problem:
Recently prescribed Savella dose pack to treat unremitting fatigue. Dx: PMR NOS. Also taking Tramadol 200 mgs. daily, 3 years for Severe Chronic Bursitis.
After 12.5 msg Savella twice daily for three days, nothing different noted.
Dose pack increase: 25 mgs twice daily for four days. After three days, noted moderate increase in energy. Dose pack increase to 50 mgs. twice daily. After three to four days felt increasingly worse: fatigued, weak, unsteady on my feet, heart rate 104 (typically 70-74). Fatigue much worse than before started Savella. Quit Savella.
Question: I read Savella interacts badly with Tramadol, but how seriously for my body, and at what dose? Savella at lower dose (25 mgs twice daily,) was such a welcome therapeutic difference in fatigue symptoms. If possible, would like to restart Savella at 25 mgs twice daily. Would I notice if an interaction with Tramadol at that dose of Savella, and would it preclude taking them together? Looking forward to your report on others experiencing these interactions and symptoms.
Pressure and clogging of ears. Don't notice I'm not hearing out of one ear or the other until hearing comes back out of the blue.
marvymuse on Mar, 8, 2013:
Too bad you had all those terrible (IMO) drugs for Fibromyalgia. Dr. Lowe (RIP) did much research on the effects of subclinical hypothyroid causing fibromyalgia. Treating with T3 has been very helpful to many, including me. Do a google search re -- fibromyalgia Lowe thyroid -- and perhaps you can feel better without drugs, per se. When I got my T3 (I don't take synthroid at all) optimized, all pain went away, I was happy, vigorous and normal (for me
Carolyn on Jul, 17, 2012:
I an a female who was told I had fibromyalsia when I was 15. I was 16 when my DR perscribed me Flexeril, Neurontin, and Tramadol together. I took the right dosage and followed directions and I ended up in the hospital twice. I started hallucinating and I was very paranoid. I couldt stop bouncing my legs up and down in the car ride to the hospital and I couldnt stop crying, I was seeing wierd things and I felt like someone was going to open the car door and drag me out. It was awful and I was really scared. The best part is, is that the hospital called my DR 3 times to let him know that he poisoned me and gave me a bad mixture of medicine, but he never answered or returned the hospitals calls. Thankfully I was ok after the drugs were out of my system. I have taken the Flexeril and the Neurontin separately and have had no problems like this one.
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- A study of drug interactions between Avonex, Neurontin, Baclofen, Clonazepam, Ultram, Propranolol for a patient with Multiple Sclerosis. The patient has Affect Lability, Anger, Anxiety, Brain Contusion, Cardio-respiratory Arrest, Cerebral Haemorrhage, Clavicle Fracture, Cognitive Disorder, Coma, Condition Aggravated, Contusion, Depression, Hallucination, Insomnia, Laceration, Pain, Psychiatric Symptom, Rib Fracture, Road Traffic Accident, Scar
- A study of drug interactions between Baclofen, Diazepam, Tramadol Hcl, Gabapentin, Hydromorphone Hcl, Clonidine for a patient with Muscle Spasticity. The patient has Drug Ineffective, Muscular Weakness, Orthostatic Hypotension, Somnolence
- A study of drug interactions between Levaquin, Avonex, Lopressor, Meclizine, Hygroton, Cartia Xt, Potassium Chloride, Neurontin, Prevacid, Ultram, Baclofen, Seroquel, Folic Acid, Skelaxin, Toradol, Lasix, Vasotec for a patient with Cellulitis. The patient has Accidental Overdose, Arthralgia, Confusional State, Headache, Medication Error, Myalgia, Nausea
- A study of drug interactions between Ultram, Paxil, Depakote, Neurontin, Baclofen for a patient with Back Pain. The patient has Convulsion, Insomnia, Nerve Compression, Pain, Spinal Laminectomy
- A study of drug interactions between Avonex, Dyazide, Atenolol, Cefprozil, Naproxen, Ibuprofen, Baclofen, Tramadol Hcl, Lortab, Gabapentin, Femhrt, Prednisone for a patient with Multiple Sclerosis. The patient has Arthropod Bite, Basal Cell Carcinoma, Cellulitis, Drug Hypersensitivity, Electrocardiogram St Segment Abnormal, Electrocardiogram T Wave Abnormal, Hypertension, Multiple Sclerosis Relapse, Nasopharyngitis, Nausea, Neurological Symptom, Urinary Tract Infection, Vomiting
- A study of drug interactions between Ultram, Paxil, Depakote, Neurontin, Baclofen for a patient with Back Pain. The patient has Convulsion, Insomnia, Nerve Compression, Pain, Spinal Laminectomy
- A study of drug interactions between Avonex, Paxil, Elavil, Clarinex, Nexium, Neurontin, Ultram, Flexeril, Provigil, Coumadin, Hyzaar, Baclofen, Ultracet for a patient with Multiple Sclerosis. The patient has Antiphospholipid Antibodies Positive, Arthritis, Condition Aggravated, Deep Vein Thrombosis, Dyspnoea, Hypertension, Pulmonary Embolism, Thrombophlebitis
- A study of drug interactions between Avonex, Dyazide, Atenolol, Cefprozil, Naproxen, Ibuprofen, Baclofen, Tramadol Hcl, Lortab, Gabapentin, Femhrt for a patient with Multiple Sclerosis. The patient has Arthropod Bite, Cellulitis, Multiple Sclerosis Relapse, Nasopharyngitis, Nausea, Urinary Tract Infection, Vomiting
- A study of drug interactions between Oxycontin, Ritalin, Ultram, Prozac, Klonopin, Vistaril, Percocet, Marcaine, Hydromorphone Hcl, Tylenol, Ancef, Actiq, Valium, Senokot, Dulcolax, Aspirin, Lovenox, Desyrel, Roxicodone, Dilaudid, Oruvail, Baclofen, Soma, Catapres-tts-1, Skelaxin, Nadolol, Amoxil, Fosamax, Neurontin, Hydroxyzine Pamoate, Celebrex, Provigil, Wellbutrin Sr, Trazodone Hcl, Dostinex, Oxycodone Hcl for a patient with Pain. The patient has Adjustment Disorder With Depressed Mood, Affective Disorder, Anorexia, Anxiety, Arthralgia, Back Pain, Blood Follicle Stimulating Hormone Decreased, Blood Luteinising Hormone Decreased, Blood Testosterone Free Decreased, Body Height Decreased, Bone Density Decreased, Bursitis, Buttock Pain, Cellulitis, Constipation, Disturbance In Attention, Dizziness, Drug Dependence, Drug Tolerance, Drug Withdrawal Syndrome, Fall, Fatigue, Feeling Cold, Groin Pain, Headache, Hot Flush, Hypersomnia, Hypoaesthesia, Incontinence, Insomnia, Irritability, Lethargy, Muscle Cramp, Muscle Spasms, Musculoskeletal Disorder, Nausea, Nervousness, Night Sweats, Pain, Pituitary Tumour Benign, Pruritus, Pyrexia, Radiculopathy, Sedation, Sinusitis, Somnolence, Temperature Intolerance, Tremor, Vision Blurred, Vomiting, Walking Aid User
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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