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From FDA reports: drug interactions between Lithium, Clozaril

This is a study of Lithium, Clozaril drug interactions. The study is created by eHealthMe based on reports of 603 people who take the same drugs and have drug interactionsfrom FDA.

On Jan, 26, 2015: 603 people who reported to have interactions when taking Lithium, Clozaril are studied

Trend of Lithium, Clozaril's drug interactions, side effects, and effectiveness reports (2928994)

Information of the patient in this study:

Conditions: Schizophrenia

Drugs taking:
- Lithium
- Clozaril

Drug interactions have: Therapeutic Agent Toxicity, Cardiac Arrest

eHealthMe real world results:

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
Therapeutic Agent Toxicity (poisoning by ability to cure substance)18 (2.99%)
Cardiac Arrest20 (3.32%)

Most common interactions experienced by people in the use of Lithium, Clozaril:

InteractionNumber of reports
Granulocytopenia (lack of granulocyte)131
Neutropenia (an abnormally low number of neutrophils)119
Pyrexia (fever)85
Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)62
White Blood Cell Count Decreased60
White Blood Cell Count Increased56
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)50
Convulsions Nos46

Most common interactions experienced by people in long term use of Lithium, Clozaril:

InteractionNumber of reports
White Blood Cell Count Decreased16
Granulocytopenia (lack of granulocyte)15
Lower Respiratory Tract Infection14
Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell)12
Confusional State8
Platelet Count Decreased8
Dysarthria (speech disorder)8
Malaise (a feeling of general discomfort or uneasiness)8
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe)8

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:




Comments from related studies:

  • From this study (4 years ago):

  • elizabeth on Mar, 29, 2011:

    my sisterhas been on clozaril foryears ended up with diabetes,renal insufficiency, pericardial effusion,thyroid goiter,just had carotid endardectomy, fell, lithium toxic,on no cogentin, for her tardive dyskonesia which makes no sense , just found out prior to hersurgery yer lithium level was 1. something they said on the high side, and her lithium was not decreased, i am very upset


Can you answer these questions (Ask a question):

More questions for: Cardiac Arrest, Clozaril, Schizophrenia, Therapeutic Agent Toxicity

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    38 year old mother of four, non smoking, no drugs, 5'6" 135 pounds, active healthy lifestyle, Family History of heart disease, only medications taken we Adderall XR 20 1 time per day from 2007-2009. I w0uld love to take part of any study to find out if the Adderall has any relation to the cardiac ar ...

More reviews for: Cardiac Arrest, Clozaril, Schizophrenia, Therapeutic Agent Toxicity

Complete side effects:

In-depth study of side effects (who have it, when it happens and how):

Could it be a symptom from a condition:

Drug effectiveness in real world:

Alternative drugs:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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