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What could cause Insomnia, Depression, Muscle Swelling for a 75-year old man?

This is a personalized study for a 75 year old male patient who has Diabetes Mellitus Non-insulin-dependent, Hypertension, Hypercholesterolemia, Treatment - hives. The study is created by eHealthMe based on reports of 44 male patients aged 75 (±5) who take the same drugs from FDA and social media.

What are the drugs

Metformin hydrochloride (latest outcomes from 14,601 users) has active ingredients of metformin hydrochloride. It is often used in diabetes.

Glyburide (latest outcomes from 26,042 users) has active ingredients of glyburide. It is often used in diabetes.

Ramipril (latest outcomes from 31,847 users) has active ingredients of ramipril. It is often used in high blood pressure.

Lipitor (latest outcomes from 132,722 users) has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol.

Niacin (latest outcomes from 6,311 users) has active ingredients of niacin. It is often used in high blood cholesterol.

Diphenhydramine hydrochloride (latest outcomes from 2,993 users) has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia.

What are the conditions

Diabetes mellitus non-insulin-dependent (latest reports from 91,190 patients) can be treated by Metformin Hydrochloride, Metformin, Januvia, Glimepiride, Actos, Glipizide.

Hypertension (high blood pressure) (latest reports from 327,932 patients) can be treated by Lisinopril, Atenolol, Metoprolol Tartrate, Amlodipine Besylate, Ramipril, Hydrochlorothiazide.

Hypercholesterolemia (high levels of cholesterol in the blood) (latest reports from 158,202 patients) can be treated by Simvastatin, Lipitor, Crestor, Pravastatin Sodium, Zocor, Atorvastatin Calcium.

Treatment - hives (latest reports from 1,014 patients) can be treated by Benadryl, Zyrtec, Prednisone, Xyzal, Atarax, Allegra.

What are the symptoms

Insomnia (sleeplessness) (latest reports from 135,811 patients) has been reported by people with depression, quit smoking, high blood pressure, pain, stress and anxiety.

Depression (latest reports from 254,062 patients) has been reported by people with quit smoking, multiple sclerosis, pain, osteoporosis, acne.

Muscle swelling (latest reports from 335 patients) has been reported by people with high blood cholesterol, high blood pressure, acromegaly, pain, hepatitis b.

On Oct, 28, 2014: 44 males aged 70 (±5) who take Metformin Hydrochloride, Glyburide, Ramipril, Lipitor, Niacin, Diphenhydramine Hydrochloride are studied

Metformin Hydrochloride, Glyburide, Ramipril, Lipitor, Niacin, Diphenhydramine Hydrochloride outcomes

Information of the patient in this study:

Age: 70

Gender: male

Conditions: Diabetes Mellitus Non-insulin-dependent, Hypertension, Hypercholesterolemia, Treatment - hives

Drugs taking:
- Metformin Hydrochloride - 500MG (metformin hydrochloride): used for 5 - 10 years
- Glyburide - 5MG (glyburide): used for 5 - 10 years
- Ramipril - 10MG (ramipril): used for 5 - 10 years
- Lipitor - EQ 40MG BASE (atorvastatin calcium): used for 5 - 10 years
- Niacin - 500MG (niacin): used for 2 - 5 years
- Diphenhydramine Hydrochloride - 50MG/ML (diphenhydramine hydrochloride): used for 1 - 2 years

Drug interactions have: severe insomnia, moderate depression, moderate muscle swelling

eHealthMe real world results:

Comparison with this patient's adverse outcomes:

InteractionNumber of reports on eHealthMe
Insomnia (sleeplessness)4 (9.09% of males aged 70 (±5) who take the drugs)
Depression2 (4.55% of males aged 70 (±5) who take the drugs)
Muscle Swelling2 (4.55% of males aged 70 (±5) who take the drugs)

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

Symptom (click a symptom for in-depth analysis)Number of reports on eHealthMe
Insomnia in Diabetes Mellitus Non-insulin-dependent62 (0.65% of males aged 70 (±5) who have Diabetes mellitus non-insulin-dependent)
Insomnia in Hypertension359 (1.47% of males aged 70 (±5) who have Hypertension)
Insomnia in Hypercholesterolemia301 (2.27% of males aged 70 (±5) who have Hypercholesterolemia)
Insomnia in Treatment - Hives1 (7.69% of males aged 70 (±5) who have Treatment - hives)
Depression in Diabetes Mellitus Non-insulin-dependent37 (0.39% of males aged 70 (±5) who have Diabetes mellitus non-insulin-dependent)
Depression in Hypertension272 (1.11% of males aged 70 (±5) who have Hypertension)
Depression in Hypercholesterolemia209 (1.58% of males aged 70 (±5) who have Hypercholesterolemia)
Depression in Treatment - Hives1 (7.69% of males aged 70 (±5) who have Treatment - hives)
Muscle Swelling in Diabetes Mellitus Non-insulin-dependent1 (0.01% of males aged 70 (±5) who have Diabetes mellitus non-insulin-dependent)
Muscle Swelling in Hypertension5 (0.02% of males aged 70 (±5) who have Hypertension)
Muscle Swelling in Hypercholesterolemia7 (0.05% of males aged 70 (±5) who have Hypercholesterolemia)
Muscle Swelling in Treatment - Hives1 (7.69% of males aged 70 (±5) who have Treatment - hives)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Side effect (click a side effect for in-depth analysis)Number of reports on eHealthMe
Insomnia in Metformin Hydrochloride20 (1.19% of males aged 70 (±5) who take Metformin hydrochloride)
Insomnia in Glyburide57 (1.40% of males aged 70 (±5) who take Glyburide)
Insomnia in Ramipril46 (0.94% of males aged 70 (±5) who take Ramipril)
Insomnia in Lipitor263 (1.84% of males aged 70 (±5) who take Lipitor)
Insomnia in Niacin18 (1.71% of males aged 70 (±5) who take Niacin)
Insomnia in Diphenhydramine Hydrochloride3 (2.10% of males aged 70 (±5) who take Diphenhydramine hydrochloride)
Depression in Metformin Hydrochloride8 (0.48% of males aged 70 (±5) who take Metformin hydrochloride)
Depression in Glyburide51 (1.26% of males aged 70 (±5) who take Glyburide)
Depression in Ramipril29 (0.59% of males aged 70 (±5) who take Ramipril)
Depression in Lipitor292 (2.04% of males aged 70 (±5) who take Lipitor)
Depression in Niacin12 (1.14% of males aged 70 (±5) who take Niacin)
Depression in Diphenhydramine Hydrochloride3 (2.10% of males aged 70 (±5) who take Diphenhydramine hydrochloride)
Muscle Swelling in Metformin Hydrochloride1 (0.06% of males aged 70 (±5) who take Metformin hydrochloride)
Muscle Swelling in Glyburide1 (0.02% of males aged 70 (±5) who take Glyburide)
Muscle Swelling in Ramipril1 (0.02% of males aged 70 (±5) who take Ramipril)
Muscle Swelling in Lipitor3 (0.02% of males aged 70 (±5) who take Lipitor)
Muscle Swelling in Niacin2 (0.19% of males aged 70 (±5) who take Niacin)
Muscle Swelling in Diphenhydramine Hydrochloride1 (0.70% of males aged 70 (±5) who take Diphenhydramine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Metformin Hydrochloride is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
n/an/a
Glyburide is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
n/an/a
Ramipril is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
n/an/a
Lipitor is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
n/an/a
Niacin is effectiven/an/an/an/a0.00%
(0 of 1 people)
n/an/an/a
Diphenhydramine Hydrochloride is effectiven/an/an/a100.00%
(1 of 1 people)
n/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
n/an/an/aMuscle SwellingMuscle SwellingMuscle Swellingn/aCerebrovascular Accident
DepressionDepressionDepressionBlood Glucose Increased
InsomniaInsomniaInsomniaDizziness
Headache
Fatigue
Asthenia
Oedema Peripheral
Listless
Polyp
Haemoglobin Decreased

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

You are not alone! Join a related mobile support group:
- support group for people who have Diabetes Mellitus Non-insulin-dependent
- support group for people who have Hypercholesterolemia
- support group for people who have Hypertension
- support group for people who have Treatment - Hives
- support group for people who have Depression
- support group for people who have Insomnia
- support group for people who have Muscle Swelling
- support group for people who take Diphenhydramine Hydrochloride
- support group for people who take Glyburide
- support group for people who take Lipitor
- support group for people who take Metformin Hydrochloride
- support group for people who take Niacin
- support group for people who take Ramipril

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

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    I was on Accupril 5 mg for more than 10 years with little or no side effects. I was diagnosed with early Type 2 diabetes and the doctor prescribed Metformin 500 mg 2 tablets a day. After about 3 months, the blood pressure was too low 88 Sistolic 45 diastolic and suffered syncope. I reduced Accupr ...

  • What can cause shortage of breath on exertion?
    (Asked by a 75 year old man who has Osteoarthritis Generalised, Shortness Of Breath, and takes Ramipril, Atenolol)
    My main problem besides the general aches and stiffness which tends to happen as you age, is a shortness of breath if I am sitting doing nothing i don't seem to notice any problem with my breathing, but as soon as I get up and walk I really struggle .This problem appeared about two year ago , when I ...

  • What dosage of metoprolol tartrate can i use to replace 50mg of motoprolol succinate er?
    (Asked by a 72 year old man who has High Blood Pressure, and takes Sertraline, Nifedipine, Hydrochlorothiazide, Terazosin Hydrochloride, Glipizide, Metformin, Potassium Citrate, Allopurinol, Fenofibrate, Simvastatin)
    I am currently taking Metoprolol Succinate 50 ER once per day, and I want to switch to Metoprolol Tartrate strictly because it is considerably cheaper. I just need to know the Tartrate equivalency for my Succinate dosage. I believe that it is 25 MG twice per day but I am not sure.

  • I am a male 72 yrs have been dieting while taking gabapentin, not losing weight is there a connection
    (Asked by a 72 year old man who has Heart Disease Congenital, and takes Atorvastatin Calcium, Metoprolol Tartrate, Rabeprazole, Gabapentin, ASA, Ipratropium Bromide)
    is there a connection with my lack of weight loss and gabapentin? I consume about 1300-1400 calories per day but don't lose weight this after losing 20lbs before taking gabapentin

  • Does cinnamon cause bleeding of the nose?
    (Asked by a 73 year old man who has Type 2 Diabetes, High Blood Pressure, Arthritis, and takes Metformin, Propranolol Hydrochloride, Benazepril Hydrochloride, Amlodipine, Etodolac)
    Nose bleed 24 hours after taking a 1 tablespoon of cinnamon mixed with honey. I have taken cinnamon mixed with honey to help my diabetes for over a year. I started having nose bleeds on a regular about six months ago. I stopped taking the mixture for over two weeks and did not have a nose bleed du ...

More questions for: Depression, Diabetes Mellitus Non-insulin-dependent, Hypercholesterolemia, Hypertension, Insomnia, Muscle Swelling, Treatment - hives

You may be interested at these reviews (Write a review):

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    (Posted by a 58 year old woman who has Hair Loss, and takes Metformin Hydrochloride)
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More reviews for: Depression, Diabetes Mellitus Non-insulin-dependent, Hypercholesterolemia, Hypertension, Insomnia, Muscle Swelling, Treatment - hives

Related drug interaction studies:

Drug effectiveness in real world:

Complete drug side effects:

Alternative drugs:

Drugs associated with:

Conditions associated with:

Recent related drug studies (Check your drugs):

More related studies for: Depression, Diabetes Mellitus Non-insulin-dependent, Hypercholesterolemia, Hypertension, Insomnia, Muscle Swelling, Treatment - hives

Common symptoms:

Men of age 60+ with Diabetes Mellitus Non-insulin-dependent:
  1. Blood glucose increased (4,227 reports)
  2. Weight decreased (2,469 reports)
  3. Nausea (2,269 reports)
  4. Hypoglycemia (1,584 reports)
  5. Blood glucose decreased (1,398 reports)
  6. Appetite - decreased (1,332 reports)
  7. Renal failure acute (1,145 reports)
  8. Dizziness (1,109 reports)
  9. Nausea and vomiting (1,075 reports)
  10. Heart attack (1,005 reports)
Men of age 60+ with Hypertension:
  1. High blood pressure (4,204 reports)
  2. Blood pressure management (4,204 reports)
  3. Dizziness (3,816 reports)
  4. Hypotension (3,710 reports)
  5. Breathing difficulty (3,668 reports)
  6. Renal failure acute (3,377 reports)
  7. Weakness (3,254 reports)
  8. Diarrhea (2,730 reports)
  9. Fatigue (2,671 reports)
  10. Pneumonia (2,511 reports)
Men of age 60+ with Hypercholesterolemia:
  1. Fatigue (2,627 reports)
  2. Weakness (2,327 reports)
  3. Rashes (2,321 reports)
  4. Muscle aches (2,035 reports)
  5. Skin blushing/flushing (1,781 reports)
  6. Headache (1,413 reports)
  7. Dizziness (1,323 reports)
  8. Pain (1,163 reports)
  9. Pain in extremity (1,080 reports)
  10. Breathing difficulty (1,065 reports)
Men of age 60+ with Treatment - Hives:
  1. Fatigue (2,627 reports)
  2. Weakness (2,327 reports)
  3. Rashes (2,321 reports)
  4. Muscle aches (2,035 reports)
  5. Skin blushing/flushing (1,781 reports)
  6. Headache (1,413 reports)
  7. Dizziness (1,323 reports)
  8. Pain (1,163 reports)
  9. Pain in extremity (1,080 reports)
  10. Breathing difficulty (1,065 reports)

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

48 million health professionals and patients have studied on eHealthMe. Recent updates:

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