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What could cause Insomnia, Depression, Muscle Swelling for a 75-year old man?

This is a personalized study for a 75 year old male patient who has Diabetes Mellitus Non-insulin-dependent, Hypertension, Hypercholesterolemia, Treatment - hives. The study is created by eHealthMe based on reports of 44 male patients aged 75 (±5) who take the same drugs from FDA and social media.

What are the drugs

Metformin hydrochloride (latest outcomes from 14,598 users) has active ingredients of metformin hydrochloride. It is often used in diabetes.

Glyburide (latest outcomes from 26,041 users) has active ingredients of glyburide. It is often used in diabetes.

Ramipril (latest outcomes from 31,841 users) has active ingredients of ramipril. It is often used in high blood pressure.

Lipitor (latest outcomes from 132,700 users) has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol.

Niacin (latest outcomes from 6,308 users) has active ingredients of niacin. It is often used in high blood cholesterol.

Diphenhydramine hydrochloride (latest outcomes from 2,989 users) has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia.

What are the conditions

Diabetes mellitus non-insulin-dependent (latest reports from 220,851 patients) can be treated by Metformin Hydrochloride, Metformin, Januvia, Glipizide, Janumet, Victoza.

Hypertension (high blood pressure) (latest reports from 1,143,390 patients) can be treated by Lisinopril, Atenolol, Amlodipine Besylate, Metoprolol Tartrate, Norvasc, Diovan.

Hypercholesterolemia (high levels of cholesterol in the blood) (latest reports from 454,618 patients) can be treated by Simvastatin, Lipitor, Crestor, Pravastatin Sodium, Zocor, Atorvastatin Calcium.

Treatment - hives (latest reports from 3,374 patients) can be treated by Benadryl, Zyrtec, Prednisone, Xyzal, Atarax, Doxepin Hydrochloride.

What are the symptoms

Insomnia (sleeplessness) (latest reports from 763,667 patients) has been reported by people with depression, quit smoking, high blood pressure, pain, stress and anxiety.

Depression (latest reports from 1,155,565 patients) has been reported by people with quit smoking, multiple sclerosis, pain, osteoporosis, high blood pressure.

Muscle swelling (latest reports from 1,630 patients) has been reported by people with high blood cholesterol, high blood pressure, acromegaly, pain, rheumatoid arthritis.

On Oct, 28, 2014: 44 males aged 70 (±5) who take Metformin Hydrochloride, Glyburide, Ramipril, Lipitor, Niacin, Diphenhydramine Hydrochloride are studied

Metformin Hydrochloride, Glyburide, Ramipril, Lipitor, Niacin, Diphenhydramine Hydrochloride outcomes

Information of the patient in this study:

Age: 70

Gender: male

Conditions: Diabetes Mellitus Non-insulin-dependent, Hypertension, Hypercholesterolemia, Treatment - hives

Drugs taking:
- Metformin Hydrochloride - 500MG (metformin hydrochloride): used for 5 - 10 years
- Glyburide - 5MG (glyburide): used for 5 - 10 years
- Ramipril - 10MG (ramipril): used for 5 - 10 years
- Lipitor - EQ 40MG BASE (atorvastatin calcium): used for 5 - 10 years
- Niacin - 500MG (niacin): used for 2 - 5 years
- Diphenhydramine Hydrochloride - 50MG/ML (diphenhydramine hydrochloride): used for 1 - 2 years

Drug interactions have: severe insomnia, moderate depression, moderate muscle swelling

eHealthMe real world results:

Comparison with this patient's adverse outcomes:

InteractionNumber of reports on eHealthMe
Insomnia (sleeplessness)4 (9.09% of males aged 70 (±5) who take the drugs)
Depression2 (4.55% of males aged 70 (±5) who take the drugs)
Muscle Swelling2 (4.55% of males aged 70 (±5) who take the drugs)

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

Symptom (click a symptom for in-depth analysis)Number of reports on eHealthMe
Insomnia in Diabetes Mellitus Non-insulin-dependent62 (0.65% of males aged 70 (±5) who have Diabetes mellitus non-insulin-dependent)
Insomnia in Hypertension359 (1.47% of males aged 70 (±5) who have Hypertension)
Insomnia in Hypercholesterolemia301 (2.27% of males aged 70 (±5) who have Hypercholesterolemia)
Insomnia in Treatment - Hives1 (7.69% of males aged 70 (±5) who have Treatment - hives)
Depression in Diabetes Mellitus Non-insulin-dependent37 (0.39% of males aged 70 (±5) who have Diabetes mellitus non-insulin-dependent)
Depression in Hypertension272 (1.11% of males aged 70 (±5) who have Hypertension)
Depression in Hypercholesterolemia209 (1.58% of males aged 70 (±5) who have Hypercholesterolemia)
Depression in Treatment - Hives1 (7.69% of males aged 70 (±5) who have Treatment - hives)
Muscle Swelling in Diabetes Mellitus Non-insulin-dependent1 (0.01% of males aged 70 (±5) who have Diabetes mellitus non-insulin-dependent)
Muscle Swelling in Hypertension5 (0.02% of males aged 70 (±5) who have Hypertension)
Muscle Swelling in Hypercholesterolemia7 (0.05% of males aged 70 (±5) who have Hypercholesterolemia)
Muscle Swelling in Treatment - Hives1 (7.69% of males aged 70 (±5) who have Treatment - hives)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Side effect (click a side effect for in-depth analysis)Number of reports on eHealthMe
Insomnia in Metformin Hydrochloride20 (1.19% of males aged 70 (±5) who take Metformin hydrochloride)
Insomnia in Glyburide57 (1.40% of males aged 70 (±5) who take Glyburide)
Insomnia in Ramipril46 (0.94% of males aged 70 (±5) who take Ramipril)
Insomnia in Lipitor263 (1.84% of males aged 70 (±5) who take Lipitor)
Insomnia in Niacin18 (1.71% of males aged 70 (±5) who take Niacin)
Insomnia in Diphenhydramine Hydrochloride3 (2.10% of males aged 70 (±5) who take Diphenhydramine hydrochloride)
Depression in Metformin Hydrochloride8 (0.48% of males aged 70 (±5) who take Metformin hydrochloride)
Depression in Glyburide51 (1.26% of males aged 70 (±5) who take Glyburide)
Depression in Ramipril29 (0.59% of males aged 70 (±5) who take Ramipril)
Depression in Lipitor292 (2.04% of males aged 70 (±5) who take Lipitor)
Depression in Niacin12 (1.14% of males aged 70 (±5) who take Niacin)
Depression in Diphenhydramine Hydrochloride3 (2.10% of males aged 70 (±5) who take Diphenhydramine hydrochloride)
Muscle Swelling in Metformin Hydrochloride1 (0.06% of males aged 70 (±5) who take Metformin hydrochloride)
Muscle Swelling in Glyburide1 (0.02% of males aged 70 (±5) who take Glyburide)
Muscle Swelling in Ramipril1 (0.02% of males aged 70 (±5) who take Ramipril)
Muscle Swelling in Lipitor3 (0.02% of males aged 70 (±5) who take Lipitor)
Muscle Swelling in Niacin2 (0.19% of males aged 70 (±5) who take Niacin)
Muscle Swelling in Diphenhydramine Hydrochloride1 (0.70% of males aged 70 (±5) who take Diphenhydramine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Metformin Hydrochloride is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
n/an/a
Glyburide is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
n/an/a
Ramipril is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
n/an/a
Lipitor is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
n/an/a
Niacin is effectiven/an/an/an/a0.00%
(0 of 1 people)
n/an/an/a
Diphenhydramine Hydrochloride is effectiven/an/an/a100.00%
(1 of 1 people)
n/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
n/an/an/aMuscle SwellingMuscle SwellingMuscle Swellingn/aCerebrovascular Accident
DepressionDepressionDepressionBlood Glucose Increased
InsomniaInsomniaInsomniaDizziness
Headache
Fatigue
Asthenia
Oedema Peripheral
Listless
Polyp
Haemoglobin Decreased

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a related mobile support group:
- support group for people who have Diabetes Mellitus Non-insulin-dependent
- support group for people who have Hypercholesterolemia
- support group for people who have Hypertension
- support group for people who have Treatment - Hives
- support group for people who have Depression
- support group for people who have Insomnia
- support group for people who have Muscle Swelling
- support group for people who take Diphenhydramine Hydrochloride
- support group for people who take Glyburide
- support group for people who take Lipitor
- support group for people who take Metformin Hydrochloride
- support group for people who take Niacin
- support group for people who take Ramipril

Comments from related studies:

  • From this study (3 weeks ago):

  • I have post menopausal bleeding after starting eliquis

    Reply

  • From this study (2 months ago):

  • BP ranges 125-130 over 75-87 when getting up prior to meds to 90-50 sometimes in the evening. I am a little stressed and so diphenhydramine helps me sleep along with melatonin. THese are OTC

    Reply

Post a new comment    OR    Read more comments

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