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What could cause Insomnia, Depression, Muscle Swelling for a 75-year old man?

This is a personalized study for a 75 year old male patient who has Diabetes Mellitus Non-insulin-dependent, Hypertension, Hypercholesterolemia, Treatment - hives. The study is created by eHealthMe based on reports of 44 male patients aged 75 (±5) who take the same drugs from FDA and social media.

What are the drugs

Metformin hydrochloride (latest outcomes from 14,594 users) has active ingredients of metformin hydrochloride. It is often used in diabetes.

Glyburide (latest outcomes from 26,036 users) has active ingredients of glyburide. It is often used in diabetes.

Ramipril (latest outcomes from 31,829 users) has active ingredients of ramipril. It is often used in high blood pressure.

Lipitor (latest outcomes from 132,675 users) has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol.

Niacin (latest outcomes from 6,307 users) has active ingredients of niacin. It is often used in high blood cholesterol.

Diphenhydramine hydrochloride (latest outcomes from 2,984 users) has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia.

What are the conditions

Diabetes mellitus non-insulin-dependent (latest reports from 220,840 patients) can be treated by Metformin Hydrochloride, Metformin, Januvia, Glipizide, Glimepiride, Victoza.

Hypertension (high blood pressure) (latest reports from 1,163,649 patients) can be treated by Lisinopril, Atenolol, Hydrochlorothiazide, Amlodipine Besylate, Metoprolol Tartrate, Norvasc.

Hypercholesterolemia (high levels of cholesterol in the blood) (latest reports from 454,536 patients) can be treated by Lipitor, Simvastatin, Crestor, Pravastatin Sodium, Zocor, Atorvastatin Calcium.

Treatment - hives (latest reports from 3,347 patients) can be treated by Benadryl, Zyrtec, Prednisone, Xyzal, Atarax, Allegra.

What are the symptoms

Insomnia (sleeplessness) (latest reports from 757,392 patients) has been reported by people with depression, quit smoking, high blood pressure, pain, stress and anxiety.

Depression (latest reports from 1,153,652 patients) has been reported by people with quit smoking, multiple sclerosis, pain, osteoporosis, high blood pressure.

Muscle swelling (latest reports from 1,630 patients) has been reported by people with high blood cholesterol, high blood pressure, acromegaly, pain, rheumatoid arthritis.

On Jul, 28, 2014: 44 males aged 70 (±5) who take Metformin Hydrochloride, Glyburide, Ramipril, Lipitor, Niacin, Diphenhydramine Hydrochloride are studied

Metformin Hydrochloride, Glyburide, Ramipril, Lipitor, Niacin, Diphenhydramine Hydrochloride outcomes

Information of the patient in this study:

Age: 70

Gender: male

Conditions: Diabetes Mellitus Non-insulin-dependent, Hypertension, Hypercholesterolemia, Treatment - hives

Drugs taking:
- Metformin Hydrochloride - 500MG (metformin hydrochloride): used for 5 - 10 years
- Glyburide - 5MG (glyburide): used for 5 - 10 years
- Ramipril - 10MG (ramipril): used for 5 - 10 years
- Lipitor - EQ 40MG BASE (atorvastatin calcium): used for 5 - 10 years
- Niacin - 500MG (niacin): used for 2 - 5 years
- Diphenhydramine Hydrochloride - 50MG/ML (diphenhydramine hydrochloride): used for 1 - 2 years

Drug interactions have: severe insomnia, moderate depression, moderate muscle swelling

eHealthMe real world results:

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
among males aged 70 (±5) who take the drugs
Insomnia (sleeplessness)4 (9.09%)
Depression2 (4.55%)
Muscle Swelling2 (4.55%)

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

Symptom (click a symptom for in-depth analysis)Number of reports
among males aged 70 (±5) who have the condition, regardless of which drug is taken
Insomnia in Diabetes Mellitus Non-insulin-dependent62 (0.66%)
Insomnia in Hypertension356 (1.46%)
Insomnia in Hypercholesterolemia300 (2.28%)
Insomnia in Treatment - Hives1 (7.69%)
Depression in Diabetes Mellitus Non-insulin-dependent37 (0.39%)
Depression in Hypertension272 (1.11%)
Depression in Hypercholesterolemia209 (1.59%)
Depression in Treatment - Hives1 (7.69%)
Muscle Swelling in Diabetes Mellitus Non-insulin-dependent1 (0.01%)
Muscle Swelling in Hypertension5 (0.02%)
Muscle Swelling in Hypercholesterolemia7 (0.05%)
Muscle Swelling in Treatment - Hives1 (7.69%)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Side effect (click a side effect for in-depth analysis)Number of reports
among males aged 70 (±5) who take the same drug
Insomnia in Metformin Hydrochloride20 (1.19%)
Insomnia in Glyburide57 (1.40%)
Insomnia in Ramipril46 (0.94%)
Insomnia in Lipitor262 (1.83%)
Insomnia in Niacin18 (1.71%)
Insomnia in Diphenhydramine Hydrochloride3 (2.10%)
Depression in Metformin Hydrochloride8 (0.48%)
Depression in Glyburide51 (1.26%)
Depression in Ramipril29 (0.59%)
Depression in Lipitor292 (2.04%)
Depression in Niacin12 (1.14%)
Depression in Diphenhydramine Hydrochloride3 (2.10%)
Muscle Swelling in Metformin Hydrochloride1 (0.06%)
Muscle Swelling in Glyburide1 (0.02%)
Muscle Swelling in Ramipril1 (0.02%)
Muscle Swelling in Lipitor3 (0.02%)
Muscle Swelling in Niacin2 (0.19%)
Muscle Swelling in Diphenhydramine Hydrochloride1 (0.70%)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Metformin Hydrochloride is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
n/an/a
Glyburide is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
n/an/a
Ramipril is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
n/an/a
Lipitor is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
n/an/a
Niacin is effectiven/an/an/an/a0.00%
(0 of 1 people)
n/an/an/a
Diphenhydramine Hydrochloride is effectiven/an/an/a100.00%
(1 of 1 people)
n/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
n/an/an/aMuscle SwellingMuscle SwellingMuscle Swellingn/aCerebrovascular Accident
DepressionDepressionDepressionBlood Glucose Increased
InsomniaInsomniaInsomniaDizziness
Headache
Fatigue
Asthenia
Oedema Peripheral
Listless
Polyp
Haemoglobin Decreased

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a related mobile support group:
- support group for people who have Diabetes Mellitus Non-insulin-dependent
- support group for people who have Hypercholesterolemia
- support group for people who have Hypertension
- support group for people who have Treatment - Hives
- support group for people who have Depression
- support group for people who have Insomnia
- support group for people who have Muscle Swelling
- support group for people who take Diphenhydramine Hydrochloride
- support group for people who take Glyburide
- support group for people who take Lipitor
- support group for people who take Metformin Hydrochloride
- support group for people who take Niacin
- support group for people who take Ramipril

Comments from related studies:

  • From this study (3 weeks ago):

  • I have post menopausal bleeding after starting eliquis

    Reply

  • From this study (2 months ago):

  • BP ranges 125-130 over 75-87 when getting up prior to meds to 90-50 sometimes in the evening. I am a little stressed and so diphenhydramine helps me sleep along with melatonin. THese are OTC

    Reply

Post a new comment    OR    Read more comments

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Related drug interaction studies:

Drug effectiveness in real world:

Complete drug side effects:

Alternative drugs:

Drugs associated with:

Conditions associated with:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

 

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