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What could cause Application Site Swelling, Binge Eating, Constipation for a 43-year old woman?

This is a personalized study for a 43 year old female patient who has Pain Management, Hypertension, Depression, Birth control and family planning. The study is created by eHealthMe based on reports of 2 female patients aged 43 (±5) who take the same drugs from FDA and social media.

What are the drugs

Methadone hydrochloride (latest outcomes from 2,824 users) has active ingredients of methadone hydrochloride. It is often used in pain.

Amlodipine besylate (latest outcomes from 19,048 users) has active ingredients of amlodipine besylate. It is often used in high blood pressure.

Paroxetine hydrochloride (latest outcomes from 3,995 users) has active ingredients of paroxetine hydrochloride. It is often used in depression.

Mirena (latest outcomes from 62,918 users) has active ingredients of levonorgestrel. It is often used in birth control.

What are the conditions

Pain management (latest reports from 1,494,216 patients) can be treated by Percocet, Tramadol Hydrochloride, Vicodin, Hydrocodone Bitartrate And Acetaminophen, Ibuprofen, Oxycontin.

Hypertension (high blood pressure) (latest reports from 1,152,135 patients) can be treated by Lisinopril, Atenolol, Amlodipine Besylate, Diovan, Hydrochlorothiazide, Metoprolol Tartrate.

Depression (latest reports from 1,161,461 patients) can be treated by Zoloft, Cymbalta, Prozac, Lexapro, Celexa, Wellbutrin Xl.

Birth control and family planning (latest reports from 135,338 patients) can be treated by Yaz, Mirena, Depo-provera, Nuvaring, Yasmin, Loestrin 24 Fe.

What are the symptoms

Application site swelling (latest reports from 2,070 patients) has been reported by people with attention deficit hyperactivity disorder, quit smoking, high blood pressure, herpes simplex, acne.

Pain medications (latest reports from 33 patients) has been reported by people with pain, birth control, high blood pressure, depression.

Binge eating (pattern of disordered eating which consists of episodes of uncontrollable eating) (latest reports from 2,231 patients) has been reported by people with insomnia, restless leg syndrome, depression, high blood pressure, quit smoking.

Constipation (latest reports from 515,750 patients) has been reported by people with osteoporosis, pain, high blood pressure, depression, high blood cholesterol.

On Oct, 31, 2014: 2 females aged 39 (±5) who take Methadone Hydrochloride, Amlodipine Besylate, Paroxetine Hydrochloride, Mirena are studied

Methadone Hydrochloride, Amlodipine Besylate, Paroxetine Hydrochloride, Mirena outcomes

Information of the patient in this study:

Age: 39

Gender: female

Conditions: Pain Management, Hypertension, Depression, Birth control and family planning

Drugs taking:
- Methadone Hydrochloride - 40MG (methadone hydrochloride): used for 1 - 6 months
- Amlodipine Besylate - EQ 10MG BASE (amlodipine besylate): used for 1 - 6 months
- Paroxetine Hydrochloride - EQ 40MG BASE (paroxetine hydrochloride): used for 1 - 2 years
- Mirena - 52MG (levonorgestrel): used for < 1 month

Drug interactions have: most severe swelling of feet and legs, severe application site swelling, most severe pain medications, severe itching - unable to provide relief by scratching excessively, most severe binge eating, most severe constipation

Comments from or about the patient: I immediately had side effects as soon as the Mirena device was implanted. The bleeding and foul discharge never ceased. I was so bloated that my ank;es were more than 2 inches around than their regulatr size. The worst issue, however, was that Mirena negated completely the effectiveness of my pain management tool - the daily doseages of methadone, that until Mirena was introduced, had worked wonders for me.
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eHealthMe real world results:

Comparison with this patient's adverse outcomes:

InteractionNumber of reports on eHealthMe
Swelling Of Feet And Legs2 (100.00% of females aged 39 (±5) who take the drugs)
Application Site Swelling2 (100.00% of females aged 39 (±5) who take the drugs)
Pain Medications2 (100.00% of females aged 39 (±5) who take the drugs)
Itching - Unable To Provide Relief By Scratching Excessively2 (100.00% of females aged 39 (±5) who take the drugs)
Binge Eating (pattern of disordered eating which consists of episodes of uncontrollable eating)2 (100.00% of females aged 39 (±5) who take the drugs)
Constipation2 (100.00% of females aged 39 (±5) who take the drugs)

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

Symptom (click a symptom for in-depth analysis)Number of reports on eHealthMe
Swelling Of Feet And Legs in Pain Management5 (0.06% of females aged 39 (±5) who have Pain management)
Swelling Of Feet And Legs in Hypertension8 (0.11% of females aged 39 (±5) who have Hypertension)
Swelling Of Feet And Legs in Depression3 (0.02% of females aged 39 (±5) who have Depression)
Swelling Of Feet And Legs in Birth Control And Family Planning3 (0.02% of females aged 39 (±5) who have Birth control and family planning)
Application Site Swelling in Pain Management3 (0.03% of females aged 39 (±5) who have Pain management)
Application Site Swelling in Hypertension1 (0.01% of females aged 39 (±5) who have Hypertension)
Application Site Swelling in Depression1 (0.01% of females aged 39 (±5) who have Depression)
Application Site Swelling in Birth Control And Family Planning4 (0.02% of females aged 39 (±5) who have Birth control and family planning)
Pain Medications in Pain Management1 (0.01% of females aged 39 (±5) who have Pain management)
Pain Medications in Hypertension1 (0.01% of females aged 39 (±5) who have Hypertension)
Pain Medications in Depression1 (0.01% of females aged 39 (±5) who have Depression)
Pain Medications in Birth Control And Family Planning1 (0.01% of females aged 39 (±5) who have Birth control and family planning)
Itching - Unable To Provide Relief By Scratching Excessively in Pain Management1 (0.01% of females aged 39 (±5) who have Pain management)
Itching - Unable To Provide Relief By Scratching Excessively in Hypertension1 (0.01% of females aged 39 (±5) who have Hypertension)
Itching - Unable To Provide Relief By Scratching Excessively in Depression1 (0.01% of females aged 39 (±5) who have Depression)
Itching - Unable To Provide Relief By Scratching Excessively in Birth Control And Family Planning1 (0.01% of females aged 39 (±5) who have Birth control and family planning)
Binge Eating in Pain Management1 (0.01% of females aged 39 (±5) who have Pain management)
Binge Eating in Hypertension3 (0.04% of females aged 39 (±5) who have Hypertension)
Binge Eating in Depression6 (0.03% of females aged 39 (±5) who have Depression)
Binge Eating in Birth Control And Family Planning2 (0.01% of females aged 39 (±5) who have Birth control and family planning)
Constipation in Pain Management242 (2.74% of females aged 39 (±5) who have Pain management)
Constipation in Hypertension175 (2.49% of females aged 39 (±5) who have Hypertension)
Constipation in Depression262 (1.39% of females aged 39 (±5) who have Depression)
Constipation in Birth Control And Family Planning138 (0.83% of females aged 39 (±5) who have Birth control and family planning)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Side effect (click a side effect for in-depth analysis)Number of reports on eHealthMe
Swelling Of Feet And Legs in Methadone Hydrochloride1 (0.28% of females aged 39 (±5) who take Methadone hydrochloride)
Swelling Of Feet And Legs in Amlodipine Besylate1 (0.27% of females aged 39 (±5) who take Amlodipine besylate)
Swelling Of Feet And Legs in Paroxetine Hydrochloride1 (0.29% of females aged 39 (±5) who take Paroxetine hydrochloride)
Swelling Of Feet And Legs in Mirena2 (0.02% of females aged 39 (±5) who take Mirena)
Application Site Swelling in Methadone Hydrochloride1 (0.28% of females aged 39 (±5) who take Methadone hydrochloride)
Application Site Swelling in Amlodipine Besylate1 (0.27% of females aged 39 (±5) who take Amlodipine besylate)
Application Site Swelling in Paroxetine Hydrochloride1 (0.29% of females aged 39 (±5) who take Paroxetine hydrochloride)
Application Site Swelling in Mirena1 (0.01% of females aged 39 (±5) who take Mirena)
Pain Medications in Methadone Hydrochloride1 (0.28% of females aged 39 (±5) who take Methadone hydrochloride)
Pain Medications in Amlodipine Besylate1 (0.27% of females aged 39 (±5) who take Amlodipine besylate)
Pain Medications in Paroxetine Hydrochloride1 (0.29% of females aged 39 (±5) who take Paroxetine hydrochloride)
Pain Medications in Mirena1 (0.01% of females aged 39 (±5) who take Mirena)
Itching - Unable To Provide Relief By Scratching Excessively in Methadone Hydrochloride1 (0.28% of females aged 39 (±5) who take Methadone hydrochloride)
Itching - Unable To Provide Relief By Scratching Excessively in Amlodipine Besylate1 (0.27% of females aged 39 (±5) who take Amlodipine besylate)
Itching - Unable To Provide Relief By Scratching Excessively in Paroxetine Hydrochloride1 (0.29% of females aged 39 (±5) who take Paroxetine hydrochloride)
Itching - Unable To Provide Relief By Scratching Excessively in Mirena1 (0.01% of females aged 39 (±5) who take Mirena)
Binge Eating in Methadone Hydrochloride1 (0.28% of females aged 39 (±5) who take Methadone hydrochloride)
Binge Eating in Amlodipine Besylate1 (0.27% of females aged 39 (±5) who take Amlodipine besylate)
Binge Eating in Paroxetine Hydrochloride2 (0.59% of females aged 39 (±5) who take Paroxetine hydrochloride)
Binge Eating in Mirena2 (0.02% of females aged 39 (±5) who take Mirena)
Constipation in Methadone Hydrochloride14 (3.91% of females aged 39 (±5) who take Methadone hydrochloride)
Constipation in Amlodipine Besylate4 (1.07% of females aged 39 (±5) who take Amlodipine besylate)
Constipation in Paroxetine Hydrochloride3 (0.88% of females aged 39 (±5) who take Paroxetine hydrochloride)
Constipation in Mirena37 (0.35% of females aged 39 (±5) who take Mirena)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Methadone Hydrochloride is effectiven/a100.00%
(1 of 1 people)
0.00%
(0 of 1 people)
n/an/an/an/an/a
Amlodipine Besylate is effectiven/a100.00%
(1 of 1 people)
n/an/an/a100.00%
(1 of 1 people)
n/an/a
Paroxetine Hydrochloride is effective0.00%
(0 of 1 people)
n/an/a100.00%
(1 of 1 people)
n/an/an/an/a
Mirena is effectiven/an/an/an/an/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Application Site SwellingApplication Site SwellingSuicide AttemptBinge Eatingn/aSuicide Attemptn/an/a
Pain MedicationsPain MedicationsConstipation
ConstipationConstipationPain Medications
Binge EatingBinge EatingApplication Site Swelling
Suicide Attempt

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

You are not alone! Join a related mobile support group:
- support group for people who have Birth Control And Family Planning
- support group for people who have Depression
- support group for people who have Hypertension
- support group for people who have Pain Management
- support group for people who have Application Site Swelling
- support group for people who have Binge Eating
- support group for people who have Constipation
- support group for people who take Amlodipine Besylate
- support group for people who take Methadone Hydrochloride
- support group for people who take Mirena
- support group for people who take Paroxetine Hydrochloride

Recent conversations of related support groups:

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Common symptoms:

Women of age 40-49 with Pain Management:
  1. Stress and anxiety (1,498 reports)
  2. Nausea (1,394 reports)
  3. Headache (1,033 reports)
  4. Depression (1,021 reports)
  5. Nausea and vomiting (935 reports)
  6. Chest pain (901 reports)
  7. Fatigue (897 reports)
  8. Breathing difficulty (886 reports)
  9. Pain in extremity (749 reports)
  10. Dizziness (714 reports)
Women of age 40-49 with Hypertension:
  1. High blood pressure (1,117 reports)
  2. Blood pressure management (1,117 reports)
  3. Headache (888 reports)
  4. Dizziness (829 reports)
  5. Chest pain (827 reports)
  6. Nausea (808 reports)
  7. Breathing difficulty (785 reports)
  8. Fatigue (757 reports)
  9. Stress and anxiety (689 reports)
  10. Pain (678 reports)
Women of age 40-49 with Depression:
  1. Stress and anxiety (2,014 reports)
  2. Nausea (1,670 reports)
  3. Fatigue (1,572 reports)
  4. Dizziness (1,518 reports)
  5. Headache (1,432 reports)
  6. Insomnia (1,382 reports)
  7. Suicidal ideation (1,176 reports)
  8. Weight increased (1,093 reports)
  9. Pain (1,025 reports)
  10. Type 2 diabetes (993 reports)
Women of age 40-49 with Birth Control And Family Planning:
  1. Nausea (1,670 reports)
  2. Fatigue (1,572 reports)
  3. Insomnia (1,382 reports)
  4. Suicidal ideation (1,176 reports)
  5. Pain (1,168 reports)
  6. Pulmonary embolism (1,074 reports)
  7. Deep venous thrombosis (1,036 reports)
  8. Chest pain (908 reports)
  9. Device expulsion (878 reports)
  10. Stress and anxiety (759 reports)

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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