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What could cause Application Site Swelling, Binge Eating, Constipation for a 43-year old woman who takes Methadone Hydrochloride, Amlodipine Besylate, Paroxetine Hydrochloride, Mirena?





Summary: 2 female patients aged 43 (±5) who take the same drugs are studied.

This is a personalized study for a 43 year old female patient who has Pain Management, Hypertension, Depression, Birth control and family planning. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Methadone Hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. (latest outcomes from Methadone Hydrochloride 2,835 users)

Amlodipine besylate has active ingredients of amlodipine besylate. It is often used in high blood pressure. (latest outcomes from Amlodipine besylate 19,061 users)

Paroxetine hydrochloride has active ingredients of paroxetine hydrochloride. It is often used in depression. (latest outcomes from Paroxetine hydrochloride 3,999 users)

Mirena has active ingredients of levonorgestrel. It is often used in birth control. (latest outcomes from Mirena 62,930 users)

What are the conditions

Pain management can be treated by Percocet, Tramadol Hydrochloride, Vicodin, Hydrocodone Bitartrate And Acetaminophen, Ibuprofen, Oxycontin. (latest reports from Pain Management 248,538 patients)

Hypertension (high blood pressure) can be treated by Lisinopril, Atenolol, Amlodipine Besylate, Hydrochlorothiazide, Diovan, Norvasc. (latest reports from Hypertension 327,932 patients)

Depression can be treated by Zoloft, Cymbalta, Prozac, Wellbutrin Xl, Celexa, Lexapro. (latest reports from Depression 254,062 patients)

Birth control and family planning can be treated by Yaz, Mirena, Depo-provera, Nuvaring, Yasmin, Loestrin 24 Fe. (latest reports from Birth Control And Family Planning 105,707 patients)

What are the symptoms

Application site swelling has been reported by people with attention deficit hyperactivity disorder, quit smoking, high blood pressure, herpes simplex, acne.(latest reports from Application site swelling 976 patients)

Pain medications has been reported by people with pain, birth control, high blood pressure, depression.(view latest reports from 33 patients)

Binge eating (pattern of disordered eating which consists of episodes of uncontrollable eating) has been reported by people with insomnia, restless leg syndrome, depression, high blood pressure, stress and anxiety.(latest reports from Binge eating 473 patients)

Constipation has been reported by people with osteoporosis, pain, high blood pressure, depression, high blood cholesterol.(latest reports from Constipation 80,049 patients)

On Dec, 3, 2014: 2 females aged 39 (±5) who take Methadone Hydrochloride, Amlodipine Besylate, Paroxetine Hydrochloride, Mirena are studied

Methadone Hydrochloride, Amlodipine Besylate, Paroxetine Hydrochloride, Mirena outcomes

Information of the patient in this study:

Age: 39

Gender: female

Conditions: Pain Management, Hypertension, Depression, Birth control and family planning

Drugs taking:
- Methadone Hydrochloride - 40MG (methadone hydrochloride): used for 1 - 6 months
- Amlodipine Besylate - EQ 10MG BASE (amlodipine besylate): used for 1 - 6 months
- Paroxetine Hydrochloride - EQ 40MG BASE (paroxetine hydrochloride): used for 1 - 2 years
- Mirena - 52MG (levonorgestrel): used for < 1 month

Drug interactions have: most severe swelling of feet and legs, severe application site swelling, most severe pain medications, severe itching - unable to provide relief by scratching excessively, most severe binge eating, most severe constipation

Comments from or about the patient: I immediately had side effects as soon as the Mirena device was implanted. The bleeding and foul discharge never ceased. I was so bloated that my ank;es were more than 2 inches around than their regulatr size. The worst issue, however, was that Mirena negated completely the effectiveness of my pain management tool - the daily doseages of methadone, that until Mirena was introduced, had worked wonders for me.
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eHealthMe real world results:

Comparison with this patient's adverse outcomes:

InteractionNumber of reports on eHealthMe
Swelling Of Feet And Legs2 (100.00% of females aged 39 (±5) who take the drugs)
Application Site Swelling2 (100.00% of females aged 39 (±5) who take the drugs)
Pain Medications2 (100.00% of females aged 39 (±5) who take the drugs)
Itching - Unable To Provide Relief By Scratching Excessively2 (100.00% of females aged 39 (±5) who take the drugs)
Binge Eating (pattern of disordered eating which consists of episodes of uncontrollable eating)2 (100.00% of females aged 39 (±5) who take the drugs)
Constipation2 (100.00% of females aged 39 (±5) who take the drugs)

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

Symptom (click a symptom for in-depth analysis)Number of reports on eHealthMe
Swelling Of Feet And Legs in Pain Management5 (0.06% of females aged 39 (±5) who have Pain management)
Swelling Of Feet And Legs in Hypertension8 (0.12% of females aged 39 (±5) who have Hypertension)
Swelling Of Feet And Legs in Depression3 (0.02% of females aged 39 (±5) who have Depression)
Swelling Of Feet And Legs in Birth Control And Family Planning3 (0.02% of females aged 39 (±5) who have Birth control and family planning)
Application Site Swelling in Pain Management3 (0.03% of females aged 39 (±5) who have Pain management)
Application Site Swelling in Hypertension1 (0.02% of females aged 39 (±5) who have Hypertension)
Application Site Swelling in Depression1 (0.01% of females aged 39 (±5) who have Depression)
Application Site Swelling in Birth Control And Family Planning4 (0.02% of females aged 39 (±5) who have Birth control and family planning)
Pain Medications in Pain Management1 (0.01% of females aged 39 (±5) who have Pain management)
Pain Medications in Hypertension1 (0.02% of females aged 39 (±5) who have Hypertension)
Pain Medications in Depression1 (0.01% of females aged 39 (±5) who have Depression)
Pain Medications in Birth Control And Family Planning1 (0.01% of females aged 39 (±5) who have Birth control and family planning)
Itching - Unable To Provide Relief By Scratching Excessively in Pain Management1 (0.01% of females aged 39 (±5) who have Pain management)
Itching - Unable To Provide Relief By Scratching Excessively in Hypertension1 (0.02% of females aged 39 (±5) who have Hypertension)
Itching - Unable To Provide Relief By Scratching Excessively in Depression1 (0.01% of females aged 39 (±5) who have Depression)
Itching - Unable To Provide Relief By Scratching Excessively in Birth Control And Family Planning1 (0.01% of females aged 39 (±5) who have Birth control and family planning)
Binge Eating in Pain Management1 (0.01% of females aged 39 (±5) who have Pain management)
Binge Eating in Hypertension3 (0.05% of females aged 39 (±5) who have Hypertension)
Binge Eating in Depression6 (0.03% of females aged 39 (±5) who have Depression)
Binge Eating in Birth Control And Family Planning2 (0.01% of females aged 39 (±5) who have Birth control and family planning)
Constipation in Pain Management242 (2.74% of females aged 39 (±5) who have Pain management)
Constipation in Hypertension155 (2.34% of females aged 39 (±5) who have Hypertension)
Constipation in Depression263 (1.39% of females aged 39 (±5) who have Depression)
Constipation in Birth Control And Family Planning138 (0.83% of females aged 39 (±5) who have Birth control and family planning)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Side effect (click a side effect for in-depth analysis)Number of reports on eHealthMe
Swelling Of Feet And Legs in Methadone Hydrochloride1 (0.28% of females aged 39 (±5) who take Methadone hydrochloride)
Swelling Of Feet And Legs in Amlodipine Besylate1 (0.27% of females aged 39 (±5) who take Amlodipine besylate)
Swelling Of Feet And Legs in Paroxetine Hydrochloride1 (0.29% of females aged 39 (±5) who take Paroxetine hydrochloride)
Swelling Of Feet And Legs in Mirena2 (0.02% of females aged 39 (±5) who take Mirena)
Application Site Swelling in Methadone Hydrochloride1 (0.28% of females aged 39 (±5) who take Methadone hydrochloride)
Application Site Swelling in Amlodipine Besylate1 (0.27% of females aged 39 (±5) who take Amlodipine besylate)
Application Site Swelling in Paroxetine Hydrochloride1 (0.29% of females aged 39 (±5) who take Paroxetine hydrochloride)
Application Site Swelling in Mirena1 (0.01% of females aged 39 (±5) who take Mirena)
Pain Medications in Methadone Hydrochloride1 (0.28% of females aged 39 (±5) who take Methadone hydrochloride)
Pain Medications in Amlodipine Besylate1 (0.27% of females aged 39 (±5) who take Amlodipine besylate)
Pain Medications in Paroxetine Hydrochloride1 (0.29% of females aged 39 (±5) who take Paroxetine hydrochloride)
Pain Medications in Mirena1 (0.01% of females aged 39 (±5) who take Mirena)
Itching - Unable To Provide Relief By Scratching Excessively in Methadone Hydrochloride1 (0.28% of females aged 39 (±5) who take Methadone hydrochloride)
Itching - Unable To Provide Relief By Scratching Excessively in Amlodipine Besylate1 (0.27% of females aged 39 (±5) who take Amlodipine besylate)
Itching - Unable To Provide Relief By Scratching Excessively in Paroxetine Hydrochloride1 (0.29% of females aged 39 (±5) who take Paroxetine hydrochloride)
Itching - Unable To Provide Relief By Scratching Excessively in Mirena1 (0.01% of females aged 39 (±5) who take Mirena)
Binge Eating in Methadone Hydrochloride1 (0.28% of females aged 39 (±5) who take Methadone hydrochloride)
Binge Eating in Amlodipine Besylate1 (0.27% of females aged 39 (±5) who take Amlodipine besylate)
Binge Eating in Paroxetine Hydrochloride2 (0.58% of females aged 39 (±5) who take Paroxetine hydrochloride)
Binge Eating in Mirena2 (0.02% of females aged 39 (±5) who take Mirena)
Constipation in Methadone Hydrochloride15 (4.18% of females aged 39 (±5) who take Methadone hydrochloride)
Constipation in Amlodipine Besylate4 (1.06% of females aged 39 (±5) who take Amlodipine besylate)
Constipation in Paroxetine Hydrochloride3 (0.88% of females aged 39 (±5) who take Paroxetine hydrochloride)
Constipation in Mirena37 (0.35% of females aged 39 (±5) who take Mirena)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Methadone Hydrochloride is effectiven/a100.00%
(1 of 1 people)
0.00%
(0 of 1 people)
n/an/an/an/an/a
Amlodipine Besylate is effectiven/a100.00%
(1 of 1 people)
n/an/an/a100.00%
(1 of 1 people)
n/an/a
Paroxetine Hydrochloride is effective0.00%
(0 of 1 people)
n/an/a100.00%
(1 of 1 people)
n/an/an/an/a
Mirena is effectiven/an/an/an/an/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Pain MedicationsApplication Site SwellingSuicide AttemptConstipationn/aSuicide Attemptn/an/a
Application Site SwellingPain MedicationsApplication Site Swelling
ConstipationConstipationBinge Eating (pattern of disordered eating which consists of episodes of uncontrollable eating)
Binge Eating (pattern of disordered eating which consists of episodes of uncontrollable eating)Binge Eating (pattern of disordered eating which consists of episodes of uncontrollable eating)Pain Medications
Suicide Attempt

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

You are not alone! Join a related mobile support group:
- support group for people who have Birth Control And Family Planning
- support group for people who have Depression
- support group for people who have Hypertension
- support group for people who have Pain Management
- support group for people who have Application Site Swelling
- support group for people who have Binge Eating
- support group for people who have Constipation
- support group for people who take Amlodipine Besylate
- support group for people who take Methadone Hydrochloride
- support group for people who take Mirena
- support group for people who take Paroxetine Hydrochloride

Recent conversations of related support groups:

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Comments from related studies:

  • From this study (2 months ago):

  • I HAVE HAD A PURITIC RED SPLOTCHY RASH OVER MOST OF MY BODY FOR THREE DAYS NOW. IT ITCHES SOME; BUT NOT SEVERELY. NO OTHER SIGNIFICANT SYMPTOMS.

    Reply

  • From this study (6 months ago):

  • want to make sure that there isn't ANY interactions with my med's

    Reply

  • From this study (8 months ago):

  • Doctor diagnosed chronic fatigue. I'm checking for other possible causes.

    Reply

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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