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What could cause Application Site Swelling, Binge Eating, Constipation for a 43-year old woman?

This is a personalized study for a 43 year old female patient who has Pain Management, Hypertension, Depression, Birth control and family planning. The study is created by eHealthMe based on reports of 2 female patients aged 43 (±5) who take the same drugs from FDA and social media.

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What are the drugs

Methadone hydrochloride (what 2,803 Methadone Hydrochloride users reported?) has active ingredients of methadone hydrochloride. It is used in pain.

Amlodipine besylate (what 19,008 Amlodipine Besylate users reported?) has active ingredients of amlodipine besylate. It is used in high blood pressure.

Paroxetine hydrochloride (what 3,978 Paroxetine Hydrochloride users reported?) has active ingredients of paroxetine hydrochloride. It is used in depression.

Mirena (what 62,889 Mirena users reported?) has active ingredients of levonorgestrel. It is used in birth control.

What are the conditions

Pain management (what 1,488,946 Pain Management patients reported?) can be treated by Tramadol Hydrochloride, Hydrocodone Bitartrate And Acetaminophen, Vicodin, Percocet, Ibuprofen, Norco.

Hypertension (what 1,161,724 Hypertension patients reported?) can be treated by Lisinopril, Amlodipine Besylate, Atenolol, Norvasc, Diovan, Hydrochlorothiazide.

Depression (what 1,148,400 Depression patients reported?) can be treated by Zoloft, Cymbalta, Prozac, Lexapro, Celexa, Wellbutrin Xl.

Birth control and family planning (what 134,284 Birth Control And Family Planning patients reported?) can be treated by Yaz, Mirena, Nuvaring, Depo-provera, Yasmin, Loestrin 24 Fe.

What are the symptoms

Application Site Swelling (what 2,013 Application Site Swelling patients reported?) has been reported by people with attention deficit hyperactivity disorder, quit smoking, high blood pressure, herpes simplex, acne.

Pain medications (what 62 Pain Medications patients reported?) has been reported by people with high blood pressure, depression, pain, birth control.

Binge Eating (pattern of disordered eating which consists of episodes of uncontrollable eating) (what 2,206 Binge Eating patients reported?) has been reported by people with insomnia, restless leg syndrome, depression, high blood pressure, quit smoking.

Constipation (what 509,285 Constipation patients reported?) has been reported by people with osteoporosis, pain, high blood pressure, depression, high blood cholesterol.

On Jul, 20, 2014: 2 females aged 39 (±5) who take Methadone Hydrochloride, Amlodipine Besylate, Paroxetine Hydrochloride, Mirena are studied

Methadone Hydrochloride, Amlodipine Besylate, Paroxetine Hydrochloride, Mirena outcomes

Information of the patient in this study:

Age: 39

Gender: female

Conditions: Pain Management, Hypertension, Depression, Birth control and family planning

Drugs taking:
- Methadone Hydrochloride - 40MG (methadone hydrochloride): used for 1 - 6 months
- Amlodipine Besylate - EQ 10MG BASE (amlodipine besylate): used for 1 - 6 months
- Paroxetine Hydrochloride - EQ 40MG BASE (paroxetine hydrochloride): used for 1 - 2 years
- Mirena - 52MG (levonorgestrel): used for < 1 month

Drug interactions have: most severe swelling of feet and legs, severe application site swelling, most severe pain medications, severe itching - unable to provide relief by scratching excessively, most severe binge eating, most severe constipation

Comments from or about the patient: I immediately had side effects as soon as the Mirena device was implanted. The bleeding and foul discharge never ceased. I was so bloated that my ank;es were more than 2 inches around than their regulatr size. The worst issue, however, was that Mirena negated completely the effectiveness of my pain management tool - the daily doseages of methadone, that until Mirena was introduced, had worked wonders for me.
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eHealthMe real world results:

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
among females aged 39 (±5) who take the drugs
Swelling Of Feet And Legs2 (100.00%)
Application Site Swelling2 (100.00%)
Pain Medications2 (100.00%)
Itching - Unable To Provide Relief By Scratching Excessively2 (100.00%)
Binge Eating (pattern of disordered eating which consists of episodes of uncontrollable eating)2 (100.00%)
Constipation2 (100.00%)

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

SymptomNumber of reports
among females aged 39 (±5) who have the condition, regardless of which drug is taken
Swelling Of Feet And Legs in Pain Management5 (0.06%)
Swelling Of Feet And Legs in Hypertension8 (0.11%)
Swelling Of Feet And Legs in Depression3 (0.02%)
Swelling Of Feet And Legs in Birth Control And Family Planning3 (0.02%)
Application Site Swelling in Pain Management3 (0.03%)
Application Site Swelling in Hypertension1 (0.01%)
Application Site Swelling in Depression1 (0.01%)
Application Site Swelling in Birth Control And Family Planning4 (0.02%)
Pain Medications in Pain Management1 (0.01%)
Pain Medications in Hypertension1 (0.01%)
Pain Medications in Depression1 (0.01%)
Pain Medications in Birth Control And Family Planning1 (0.01%)
Itching - Unable To Provide Relief By Scratching Excessively in Pain Management1 (0.01%)
Itching - Unable To Provide Relief By Scratching Excessively in Hypertension1 (0.01%)
Itching - Unable To Provide Relief By Scratching Excessively in Depression1 (0.01%)
Itching - Unable To Provide Relief By Scratching Excessively in Birth Control And Family Planning1 (0.01%)
Binge Eating in Pain Management1 (0.01%)
Binge Eating in Hypertension3 (0.04%)
Binge Eating in Depression6 (0.03%)
Binge Eating in Birth Control And Family Planning2 (0.01%)
Constipation in Pain Management241 (2.74%)
Constipation in Hypertension174 (2.50%)
Constipation in Depression261 (1.39%)
Constipation in Birth Control And Family Planning138 (0.83%)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Side effectNumber of reports
among females aged 39 (±5) who take the same drug
Swelling Of Feet And Legs in Methadone Hydrochloride1 (0.28%)
Swelling Of Feet And Legs in Amlodipine Besylate1 (0.27%)
Swelling Of Feet And Legs in Paroxetine Hydrochloride1 (0.30%)
Swelling Of Feet And Legs in Mirena2 (0.02%)
Application Site Swelling in Methadone Hydrochloride1 (0.28%)
Application Site Swelling in Amlodipine Besylate1 (0.27%)
Application Site Swelling in Paroxetine Hydrochloride1 (0.30%)
Application Site Swelling in Mirena1 (0.01%)
Pain Medications in Methadone Hydrochloride1 (0.28%)
Pain Medications in Amlodipine Besylate1 (0.27%)
Pain Medications in Paroxetine Hydrochloride1 (0.30%)
Pain Medications in Mirena1 (0.01%)
Itching - Unable To Provide Relief By Scratching Excessively in Methadone Hydrochloride1 (0.28%)
Itching - Unable To Provide Relief By Scratching Excessively in Amlodipine Besylate1 (0.27%)
Itching - Unable To Provide Relief By Scratching Excessively in Paroxetine Hydrochloride1 (0.30%)
Itching - Unable To Provide Relief By Scratching Excessively in Mirena1 (0.01%)
Binge Eating in Methadone Hydrochloride1 (0.28%)
Binge Eating in Amlodipine Besylate1 (0.27%)
Binge Eating in Paroxetine Hydrochloride2 (0.59%)
Binge Eating in Mirena2 (0.02%)
Constipation in Methadone Hydrochloride14 (3.97%)
Constipation in Amlodipine Besylate4 (1.08%)
Constipation in Paroxetine Hydrochloride3 (0.89%)
Constipation in Mirena36 (0.34%)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Methadone Hydrochloride is effectiven/a100.00%
(1 of 1 people)
0.00%
(0 of 1 people)
n/an/an/an/an/a
Amlodipine Besylate is effectiven/a100.00%
(1 of 1 people)
n/an/an/a100.00%
(1 of 1 people)
n/an/a
Paroxetine Hydrochloride is effective0.00%
(0 of 1 people)
n/an/a100.00%
(1 of 1 people)
n/an/an/an/a
Mirena is effectiven/an/an/an/an/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Application Site SwellingBinge EatingSuicide AttemptBinge Eatingn/aSuicide Attemptn/an/a
Pain MedicationsConstipationConstipation
ConstipationPain MedicationsPain Medications
Binge EatingApplication Site SwellingApplication Site Swelling
Suicide Attempt

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who have Birth Control And Family Planning
- group for people who have Depression
- group for people who have Hypertension
- group for people who have Pain Management
- group for people who have Application Site Swelling
- group for people who have Binge Eating
- group for people who have Constipation
- group for people who take Amlodipine Besylate
- group for people who take Methadone Hydrochloride
- group for people who take Mirena
- group for people who take Paroxetine Hydrochloride

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