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What could cause Drug Withdrawal Syndrome, Sweating - excessive, Pain for a 43-year old man who takes Methadone Hydrochloride, Tylenol, Aleve, Ibuprofen?





Summary: 29 male patients aged 43 (±5) who take the same drugs are studied.

This is a personalized study for a 43 year old male patient who has Pain. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Methadone Hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. (latest outcomes from Methadone Hydrochloride 2,835 users)

Tylenol has active ingredients of acetaminophen. It is often used in pain. (latest outcomes from Tylenol 55,615 users)

Aleve has active ingredients of naproxen sodium. It is often used in pain. (latest outcomes from Aleve 20,558 users)

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from Ibuprofen 61,602 users)

What are the conditions

Pain can be treated by Hydrocodone Bitartrate And Acetaminophen, Percocet, Tramadol Hydrochloride, Vicodin, Ibuprofen, Lortab. (latest reports from Pain 280,210 patients)

Pain exacerbated (latest reports from Pain Exacerbated 254,920 patients)

What are the symptoms

Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation) has been reported by people with depression, pain, stress and anxiety, ill-defined disorder, muscle spasticity.(latest reports from Drug withdrawal syndrome 32,657 patients)

Sweating - excessive (abnormally increased sweating) has been reported by people with depression, pain, high blood pressure, stress and anxiety, high blood cholesterol.(latest reports from Sweating - excessive 42,617 patients)

Pain has been reported by people with multiple sclerosis, osteoporosis, birth control, rheumatoid arthritis, high blood cholesterol.(latest reports from Pain 280,210 patients)

On Nov, 22, 2014: 29 males aged 39 (±5) who take Methadone Hydrochloride, Tylenol, Aleve, Ibuprofen are studied

Methadone Hydrochloride, Tylenol, Aleve, Ibuprofen outcomes

Information of the patient in this study:

Age: 39

Gender: male

Conditions: Pain, Pain Exacerbated

Drugs taking:
- Methadone Hydrochloride - 10MG (methadone hydrochloride): used for 2 - 5 years
- Tylenol (Mcneil Cons (acetaminophen): used for 2 - 5 years
- Aleve (naproxen sodium): used for 6 - 12 months
- Ibuprofen - 600MG (ibuprofen): used for 6 - 12 months

Drug interactions have: moderate drug withdrawal syndrome, moderate sweating - excessive, moderate pain

Comments from or about the patient: It seemed that the otc meds may have caused the methadone to wear off very quickly or rush out of my system causing what feels like withdrawal symptoms
Reply the comment

eHealthMe real world results:

Comparison with this patient's adverse outcomes:

InteractionNumber of reports on eHealthMe
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)2 (6.90% of males aged 39 (±5) who take the drugs)
Sweating - Excessive (abnormally increased sweating)2 (6.90% of males aged 39 (±5) who take the drugs)
Pain2 (6.90% of males aged 39 (±5) who take the drugs)

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

Symptom (click a symptom for in-depth analysis)Number of reports on eHealthMe
Drug Withdrawal Syndrome in Pain447 (8.60% of males aged 39 (±5) who have Pain)
Drug Withdrawal Syndrome in Pain Exacerbated383 (8.28% of males aged 39 (±5) who have Pain exacerbated)
Sweating - Excessive in Pain221 (4.25% of males aged 39 (±5) who have Pain)
Sweating - Excessive in Pain Exacerbated218 (4.71% of males aged 39 (±5) who have Pain exacerbated)
Pain in Pain0 (0.00% of males aged 39 (±5) who have Pain)
Pain in Pain Exacerbated579 (12.52% of males aged 39 (±5) who have Pain exacerbated)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Side effect (click a side effect for in-depth analysis)Number of reports on eHealthMe
Drug Withdrawal Syndrome in Methadone Hydrochloride6 (2.07% of males aged 39 (±5) who take Methadone hydrochloride)
Drug Withdrawal Syndrome in Tylenol33 (2.05% of males aged 39 (±5) who take Tylenol)
Drug Withdrawal Syndrome in Aleve2 (0.32% of males aged 39 (±5) who take Aleve)
Drug Withdrawal Syndrome in Ibuprofen26 (1.00% of males aged 39 (±5) who take Ibuprofen)
Sweating - Excessive in Methadone Hydrochloride10 (3.45% of males aged 39 (±5) who take Methadone hydrochloride)
Sweating - Excessive in Tylenol46 (2.86% of males aged 39 (±5) who take Tylenol)
Sweating - Excessive in Aleve13 (2.10% of males aged 39 (±5) who take Aleve)
Sweating - Excessive in Ibuprofen44 (1.69% of males aged 39 (±5) who take Ibuprofen)
Pain in Methadone Hydrochloride11 (3.79% of males aged 39 (±5) who take Methadone hydrochloride)
Pain in Tylenol122 (7.59% of males aged 39 (±5) who take Tylenol)
Pain in Aleve28 (4.53% of males aged 39 (±5) who take Aleve)
Pain in Ibuprofen162 (6.24% of males aged 39 (±5) who take Ibuprofen)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Methadone Hydrochloride is effectiven/an/an/an/a0.00%
(0 of 1 people)
n/an/an/a
Tylenol is effectiven/an/an/an/a0.00%
(0 of 1 people)
n/an/an/a
Aleve is effectiven/an/a0.00%
(0 of 1 people)
n/an/an/an/an/a
Ibuprofen is effectiven/an/a0.00%
(0 of 1 people)
n/an/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
n/an/aDrug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)n/aSweating - Excessive (abnormally increased sweating)n/an/aNausea (feeling of having an urge to vomit)
PainPainVomiting
Sweating - Excessive (abnormally increased sweating)Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)Gliosis (a process leading to scars in the central nervous system)
Dizziness
Vertigo
Blindness
Optic Neuritis (optic nerve inflammation)
Optic Ischaemic Neuropathy (optic nerve damage due to lack of blood supply)
Haemoglobin Decreased
Optic Atrophy (the loss of a proportion of optic disc nerve fibres)

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

You are not alone! Join a related mobile support group:
- support group for people who take Methadone Hydrochloride and have Drug Withdrawal Syndrome
- support group for people who take Tylenol and have Drug Withdrawal Syndrome
- support group for people who take Aleve and have Drug Withdrawal Syndrome
- support group for people who take Ibuprofen and have Drug Withdrawal Syndrome
- support group for people who take Methadone Hydrochloride and have Sweating - Excessive
- support group for people who take Tylenol and have Sweating - Excessive
- support group for people who take Aleve and have Sweating - Excessive
- support group for people who take Ibuprofen and have Sweating - Excessive
- support group for people who take Methadone Hydrochloride and have Pain
- support group for people who take Tylenol and have Pain
- support group for people who take Aleve and have Pain
- support group for people who take Ibuprofen and have Pain
- support group for people who have Drug Withdrawal Syndrome and Pain
- support group for people who have Drug Withdrawal Syndrome and Pain Exacerbated
- support group for people who have Sweating - Excessive and Pain
- support group for people who have Sweating - Excessive and Pain Exacerbated
- support group for people who have Pain and Pain Exacerbated
- support group for people who have Pain
- support group for people who have Drug Withdrawal Syndrome
- support group for people who have Pain
- support group for people who have Sweating - Excessive
- support group for people who take Aleve
- support group for people who take Ibuprofen
- support group for people who take Methadone Hydrochloride
- support group for people who take Tylenol

Can you answer these questions (Ask a question):

More questions for: Aleve, Drug Withdrawal Syndrome, Pain, Pain Exacerbated, Sweating - excessive

You may be interested at these reviews (Write a review):

  • 3 strong drugs together against neuropathic pain
    Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.

    The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.

    The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
    What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.

    It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.

    There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.

    Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.

    The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).

    Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.

    I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
  • Nexium improves my constipation
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  • Heavy sweating during sleep
    Pain killers like Tylenol 3, vicodin 20 years, Valium and Soma 12 years. Sweat heavy during sleep.
  • Wheezing stopped after topamax sessesion
    Wheezing noted by primary physician in this non-smoker. Stopped Topamax per doctor's instruction. 48 hours later was examined by physician and noted that wheezing stopped.
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    I am having a moderate to strong reaction to poison ivy exposure. I have a localized rash with blistering, swelling and inflammation similar to cellulitis. The rash has been progressing for about a week. The blisters are not weeping or oozing. The area is cleaned daily with neem oil soap. Coincident with the rash, I have a persistent ache/pain in my lower forearm, wrist and hand that is responding weakly to Aleve and pretty much unresponsive to acetaminophen.

More reviews for: Aleve, Drug Withdrawal Syndrome, Pain, Pain Exacerbated, Sweating - excessive

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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