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Related topic: Heart Rate Decreased, Hypertension Aggravated, Ibuprofen, Metoprolol Succinate, Pain - Muscles

What could cause Hypertension Aggravated for a 55-year old man?

This is a study of Metoprolol Succinate, Ibuprofen for a 55 year old male patient who has Heart Rate Decreased, Pain - Muscles. The study is created by eHealthMe based on 162 male patients aged 55 (±5) who take the drugs from FDA and social media.

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Information of the patient in this study:

Age: 50

Gender: male

Conditions: Heart Rate Decreased, Pain - Muscles

Drugs taking:
- Metoprolol Succinate (metoprolol succinate): used for 1 - 2 years
- Ibuprofen (ibuprofen): used for < 1 month

Drug interactions have: moderate hypertension aggravated

On Feb, 2, 2014: 162 males aged 50 (±5) who reported to have interactions when taking Metoprolol Succinate, Ibuprofen are studied

Trend of Metoprolol Succinate, Ibuprofen's drug interactions, side effects and effectiveness reports (2791924)

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
among males aged 50 (±5) who take the drugs
Hypertension Aggravated (high blood pressure-aggravated)16 (9.88%)

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

SymptomNumber of reports
among males aged 50 (±5) who have the condition, regardless of which drug is taken
Hypertension Aggravated in Heart Rate Decreased1 (5.56%)
Hypertension Aggravated in Pain - Muscles20 (7.09%)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Side effectNumber of reports
among males aged 50 (±5) who take the drug
Hypertension Aggravated in Metoprolol Succinate66 (6.18%)
Hypertension Aggravated in Ibuprofen138 (3.75%)

Most common interactions experienced by males aged 50 (±5) in the use of Metoprolol Succinate, Ibuprofen:

InteractionNumber of reports
Dyspnoea (difficult or laboured respiration)54
Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)44
Fatigue (feeling of tiredness)34
Chest Pain31
Anaemia (lack of blood)30
Back Pain24
Headache (pain in head)20

Most common interactions experienced by males aged 50 (±5) in long term use of Metoprolol Succinate, Ibuprofen:

InteractionNumber of reports
Disorientation (disability in which the senses of time, direction, and recognition of people and places)6
Loss Of Consciousness5
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)5
Hypotension (abnormally low blood pressure)5
Post-thoracotomy Pain Syndrome4
Fungal Infection3
Obsessive-compulsive Personality Disorder (a mental health condition in which a person is preoccupied with rules, orderliness, and control)3
Obsessive-compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)2

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Comments from related studies:

  • From this study (3 months ago):

  • While I had the flu I began using guaifenesin and Sudafed to try to relieve the symptoms of sinus discharge, post-nasal drip and phlegm, and cough. I have mostly recovered but still cough a lot due to excessive sinus drainage and phlegm in my lungs.


  • From this study (2 years ago):

  • started 1800 mg/day ibuprofen; next day BP increased. over next 7 days readings of 170/87,171/82, 163/86, 182/84, 166/94. Stopped ibuprofen. two days later BP stabilized at 123/73.


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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Related studies

- Ibuprofen side effects
- Metoprolol Succinate side effects


Related conditions

- Heart rate decreased
- Muscle aches


Related drug side effects

- Hypertension Aggravated



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