Drug interactions between Adderall Xr 20, Vicodin, Wellbutrin Xl, Ativan, Vitamin B12, Ms Contin for a Female patient aged 37

This is a personalized study of Adderall Xr 20, Vicodin, Wellbutrin Xl, Ativan, Vitamin B12, Ms Contin drug interactions for a 37 year old female patient who has ADHD, Pain - back, Chronic depression, Anxiety Disorder, Anemia - B12 deficiency, back pain - low. The study is created by eHealthMe based on 102 reports from FDA.

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What are the drugs

Adderall xr 20 has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is used in attention deficit hyperactivity disorder, atypical attention deficit syndrome, fatigue, narcolepsy, attention deficit disorder with hyperactivity (addh), mental status tests.

Vicodin has active ingredients of acetaminophen; hydrocodone bitartrate. It is used in pain, back pain - low, back pain, surgery, pain in limb, arthritis.

Wellbutrin xl has active ingredients of bupropion hydrochloride. It is used in depression, stress and anxiety, dysthymia, major depression, depressed mood, quit smoking.

Ativan has active ingredients of lorazepam. It is used in stress and anxiety, generalized anxiety disorder, insomnia, panic disorder, sleep disorder, panic attack.

Vitamin b12 has active ingredients of cobalamin. It is used in vitamin b12 deficiency, energy increased, general physical condition abnormal, vitamin supplementation, healthy living, fatigue.

Ms contin has active ingredients of morphine sulfate. It is used in pain, back pain - low, chronic pain, fibromyalgia, neck pain, back injury.

On Apr, 16, 2013: 102 people who reported to have interactions when taking Adderall Xr 20, Vicodin, Wellbutrin Xl, Ativan, Vitamin B12, Ms Contin are studied

Information of the patient in this study:

Age: 34

Gender: female

Conditions: ADHD, Pain - back, Chronic depression, Anxiety Disorder, Anemia - B12 deficiency, back pain - low

Drugs taking:
- Adderall Xr 20 - 5MG;5MG;5MG;5MG (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate): used for 1 - 2 years
- Vicodin - 500MG;5MG (acetaminophen; hydrocodone bitartrate): used for 1 - 2 years
- Wellbutrin Xl - 300MG (bupropion hydrochloride): used for 2 - 5 years
- Ativan - 1MG (lorazepam): used for 5 - 10 years
- Vitamin B12 (cobalamin): used for 6 - 12 months
- Ms Contin (morphine sulfate)

eHealthMe real world results:

For females aged 34 (±5):

Comparison with this patient's adverse outcomes:

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Most common interactions experienced by females aged 34 (±5) in the use of Adderall Xr 20, Vicodin, Wellbutrin Xl, Ativan, Vitamin B12, Ms Contin:

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Most common interactions experienced by females aged 34 (±5) in long term use of Adderall Xr 20, Vicodin, Wellbutrin Xl, Ativan, Vitamin B12, Ms Contin:

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For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many HBP patients have nausea)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many Aspirin users have nausea)

Most common interactions experienced by people in the use of Adderall Xr 20, Vicodin, Wellbutrin Xl, Ativan, Vitamin B12, Ms Contin:

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Most common interactions experienced by people in long term use of Adderall Xr 20, Vicodin, Wellbutrin Xl, Ativan, Vitamin B12, Ms Contin:

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Drug effectiveness in real world:

• Adderall Xr 20 for ADHD reported by 454 people (updated 1 week ago)
• Vicodin for Pain - Back reported by 124 people (updated 2 weeks ago)
• Wellbutrin Xl for Chronic Depression reported by 104 people (updated 2 months ago)
• Ativan for Anxiety Disorder reported by 182 people (updated 17 hours ago)
• Vitamin B12 for Anemia - B12 Deficiency reported by 15 people (updated 2 months ago)
• Ms Contin for Back Pain - Low reported by 16 people (updated 5 months ago)

Side effects in real world:

• Browse all Adderall xr 20 side effects: 636 in total

  A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z 

• Browse all Vicodin side effects: 8,077 in total

  A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z 

• Browse all Wellbutrin xl side effects: 3,373 in total

  A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z 

• Browse all Ativan side effects: 8,133 in total

  A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z 

• Browse all Vitamin b12 side effects: 2,684 in total

  A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z 

• Browse all Ms contin side effects: 4,493 in total

  A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z 

Alternative drugs:

• Adhd (66 drugs) (updated 14 hours ago)
• Anemia - B12 Deficiency (4 drugs) (updated 1 month ago)
• Anxiety Disorder (81 drugs) (updated 9 hours ago)
• Back Pain - Low (112 drugs) (updated 2 days ago)
• Chronic Depression (53 drugs) (updated 2 days ago)
• Pain - Back (112 drugs) (updated 2 days ago)

Drugs in real world that are associated with:

• Nausea And Vomiting

Comments from related studies:

• From this study (1 week ago):

peanuts on Mar, 31, 2010:

my friend is suffering from rhumatory arthertis.and is currenty taking cocaine. oxy cotin,prestine, wellbutrim, predisone 10mg what side effects should she expect ?????

Reply

jimmy on Apr, 29, 2013:

Susan,
Finally, I'd been reading thru here and finnaly, what doctor in the U.S. still prescribes cocaine? LOL

Reply

jimmy on Apr, 29, 2013:

IF you donT see my other comments, Never take Cymbalta or anything containing same ingrediants or speeding thru the same side effects durring their enjoyable living advertizements!

Reply

Jmsrocks on Jul, 25, 2012:

Probably death. Cocain and opiates together = speed ball.

Reply

Hebe on Jul, 31, 2012:

I have had two close relatives on prednisone, and for both of them it alone can make them feel really speedy. Combined with cocaine and wellbutrin would probably make sleeping very difficult. As the previous commenter mentioned, combining oxys into this is probably a bit dangerous.

Reply

Patty O'Neill on Aug, 10, 2012:

The comments about death in combination with cocaine and opiates or any other drug is possible
depending on how much and the situation. Frightening people is not the key here. Basically any drug in combination with another could cause a major health problem as we are all very much not the same makeup. Cheers,

Reply

ken on Aug, 17, 2012:

If she continues with this type of treatment, its kinda scary in all reality. Why not see a doctor, that's where the healing may start.

Reply

Jackie on Apr, 30, 2013:

I am wondering if you were diagnosed because you had pain and found out you had a neurological message going on.... or just a process of elimination over the pain after you were taking your anti psychotic medication? I've been taking oxycone for my pain my back and neck disc issues um for about a year now, was having joint pain and stiffness all over my body the Dr put me on cymbalta and now three weeks later he put me on wellbutrin and I'm wondering about seratonin syndrome... I'm having muscle twitching also lump on top of my head and vision problems.

Reply

iCaNtCaLlIt on Oct, 24, 2012:

Please coke for arthrit.? take your fish oils 2 each meal and take your perscribed pain meds(careful very addicting) stop the coke thats being silly for real. goodluck, lifes a bych and ya die thats why we get high .. p.s ankle 9 surgerys plates screws never walk normal again, fight thru it..i got hurt at work btw 7 ton crushed my leg instead of me....jus always think thingd can be worse, be a gpod person dont let this bring u dwn n b miserable..pul thru keep head up n watch those pain meds..goodluck...email if u wana talk but dont come with negatibity. buhbye

Reply

susan on Jan, 3, 2013:

have vit d blood levles ck, and supplenment. vit d is an amazing pain control helper.

Reply

nefariouson3 on Nov, 7, 2012:

I too am a chronic pain sufferer, I drove over a explosive in the middle-east. I don't understand what or why this thread was written up like a true medical study, to me it looks more like a recreational train wreck, some listed drugs have reverse reactions and others simply have no medical need what so ever, personally I would seek professional help and attempt to get off the unneeded drugs and concentrate on the true medical issues. At your age 51, you run the risk of many complications and possibility death from the listed drugs, though who am I to judge, life is way too short enjoy it when your still alive.

Th3

Reply

Had'em all on Nov, 14, 2012:

Prison and/or death. Comparing taking coke by inhalation and oxycontin orally is NOT the same thing as speed ball. Kindergarten speed ball maybe. Addiction threshold of oxy is 60mg/day. She should try to stay below that.
Get her the hell off Pristine/Ketoconazole unless it is absolutely positively necessary. If necessary, try to get a lower dose. Stuff fries the liver & with all the other crap--BAD idea.
Is there a reason she isn't taking an NSAID? I see prednisone. Would help more than oxy.

Reply

kobe77 on Jan, 3, 2013:

Lmao! Lmao! You sound like your high ......enjoy your trip!

Reply

knowledgable on Jan, 7, 2013:

Death bed us what they should expect. Mixing cocaine and oxy, are they brainless!!!!

Reply

Sydney on Jan, 9, 2013:

Tell your friend to GET OFF WHEAT. The wheat products in this country are GMO which are very bad for us and cause arthritis. Tell your friend to research. Never let the Dr.s try and figure out what's wrong with you. They won't. And they'll kill you trying.

Reply

nursing101 on Jan, 28, 2013:

Well, NSAID, you say? Hmmm....I see motrin, naproxen and aspirin on the list....all NSAID's

Reply

Billy on Feb, 2, 2013:

It is a wonder that your wife is at all coherent taking that cocktail of medications. I would try to find a new doctor that has a better grasp of toxicology and drug interactions. Cocaine and Oxycotin--can't belief any reputable doctor would prescribe that combination.

Reply

High depression low motivation on Feb, 8, 2013:

I take fish oils and centrum vitamins for depression replacing latuda and Lexapro wich was messing with my school I was out of phase sleeping all day and cloudy thinking. Now I just take Adderall and Xanax for agoraphobia and I feel a lot better and Im actually doing homework!! I scored high on my test than on the antidepressants with low scores.

Reply

AdoreTu on Mar, 4, 2013:

Well, I just stopped at your post, and who ever is taking all of that stuff needs to take some Milk Thistle to help restore their liver.

Reply

Sam on Mar, 11, 2013:

Way back in the late 1960's I heard it called a combination of cocaine and opiate type drugs a speedball. My best guess is your friend is on the way out of this world, unless there is an intervention. In short, death is the end result/side effect of taking such a combination of drugs....

Deo Vindece,

Sam

Reply

BCS on Mar, 12, 2013:

Honestly. She can expect to die very young.

Everything from heart, kidney, liver, stomach, brain, lungs, immune system, etc. will began to shut down.
She will most likely become increasingly weak, finding herself in the hospital more often, and eventually die of organ failure. that is unless she dies from an overdoes first.

Reply

bcs on Mar, 12, 2013:

Yeah, hybrid wheat is causing all the problems. not the cocaine and oxy, mixed with other prescription drugs.

I agree Hybrid wheat is harmful and best left out of ones diet, but it's not the biggest problem here. (it hybrid not gmo) they haven't released that yet.

Reply

Susan on Mar, 12, 2013:

Are you guys really this dumb? She meant to say her friend was taking Codeine not cocaine. I'm not even going to bother asking a question on this website if you're that dumb! LOL

Reply

Jenn on Mar, 15, 2013:

I know that I am super sensitive to both codeine and oxy. They actually make me more nauseous and dizzy and i find regular tylenol or ibuprophen to be more effective against pain. I have heard some good things about omega fish oil and gluten free diets. My sister has RA too and when she flares up even pain meds dont help much. She is also gluten intolerant and can feel a marked difference in symptoms when she "slips" and eats gluten-y things. Steroids make your blood pressure high, she takes them when she gets flare ups but tries to ween herself off as the flare up dissipates. She gets weird skin breakouts because steroids also mess with the natural flora of your body. RA sux!!!!

Reply

doc moc on Mar, 25, 2013:

have tou tried cocaine? pretty sure its gluten free our previous inquisitor seemed to have some luck with its administration in combination with an assortment of other medications to treat her condition also as far as the flora issue goes i dont think cocaine is an antagonist

Reply

doc moc on Mar, 30, 2013:

oh yes BCS i agree hybrid wheat is a very dangerous substance especially when compared to the rather inocuous substances of cocaine and oxycontin! just what are your qualifications to dispense such well researched and supported opinions? You are truly a fool

Reply

Stephanie on Apr, 1, 2013:

Yeah I'm pretty sure she ment codeine. i dont visit these sites often anymore becasue my questions never get answered and everything gets way off topic.

Reply

really on Apr, 10, 2013:

people like you should visit your local humane society and have yourself spayed or neutered because the human race does not need less intelligent, human-jackass hybrid beings breeding with those of greater intellect. Cocaine was clearly written, not codeine. and please don't post your questions, prefer you be the guinea pig and take risks alerting the people who matter of potential risk factors. :)

Reply

Robert on Apr, 12, 2013:

I just wish the federal government would overhaul Richard Nixon's war on drugs and the whole controlled drug act. I have had my share of pain and you can consider yourself lucky to be able to cope with it. It is the sorry folk out there who have psychiatric disorders which affect the brain's ability to "deal" and cope, and is at a chemical level with them, a neurological mess-up. I know personally, I have phases of time when it is dangerous for me to try and tough it out when my brain sometimes slows down production and release of the natural chemicals like beta endorphin, dopamine, Gammaaminobuteric Acid, and I can find my body aches because Im not making enough natural opiate substances. SO I take drugs given by MD to make me feel normal, like clonazepam, prozac, and sometimes amphetamine in low doses. It is frustrating because people still don't understand and think I am a schmuck for taking drugs to feel normal happiness, calm, joy, relaxation, and to enjoy life's natural pleasures I periodically am unable to feel or appreciate.

Reply

Robert on Apr, 12, 2013:

It is true that speedballs, containing opiates and any stimulant. The "speed" in speedball likely refers to amphetamine, which was, prior to 1970, the original or at least most widely used upper in the 1960's. When the Controlled Drug Act was made official, cocaine became hugely popular, as an easier and more available alternative. SO strangely enough it became easier to get a totally outlawed drug than legal controlled drugs, because the new DEA and their most overzealous zealots were too busy finally settling old scores and getting the "dopeheads" and "speedfreeks" with the new Nixonian legislation backing them up like the word of God

Reply

Michele on Apr, 12, 2013:

I totally understand where you are coming from. Your comment at the end there helped me understand that I am not "a druggy" as my husband calls me because I need medications to feel an enjoy simple life activities. You're lucky to have found the right combination of medicines to treat your depression. I feel like I've been on a roller coaster for the last 20 years. If I find the "right" combination to treat my severe depression/bipolar2 disorders, then I find myself with one or more intolerable side effects that I must live with, like extreme teeth pain/bruxism. I look at people all the time and say to myself "That person is "normal." "That person is enjoying life." "That person sleeps normally and doesn't need help." "That person is a good mom for doing activities with her child/children." I get sorta jealous, then I start believing what my husband says about me being a druggy and that I am not a good teacher/mom/wife. That I shouldn't need medicine to just have energy to get up and get dressed. But when I read your post it made me feel good, not that you were dealing with depression, but that someone else out there understands how it feels, that my husband is dead wrong and out of line, that my depression is a real disorder and not my fault. Thank you for your post.

Reply

shannon on Apr, 13, 2013:

What shouldnt the expexation be...yes, cocaone is an antisthetic...only local, dentists "pink" mouth swab is cocaine based to numb the area and costrict blood vessels toz reduce swelling and bleeding....not for arthritis!..sounds like its a way to find a way out faster by destroying the heart muscle fro. The cocke's super stimulative effect and leave this world. There are other means to treat pain than death and mega doses of narcotics to mask the pain and increase the tolernance of the mds to the point that either there are no interior sinuses lrft by coke use or not enough pain meds to overcome the tolerance....ven IV cocaine use will burn the veins you shoot it in...its a loosing battle...and a painful one from damag thats beendone...Im praying for you guys...

Reply

Russ on May, 7, 2013:

Formally of you bashing the cocaine for pain, do some research! Brompton's Cocktail is a chronic pain medicine in liquid form that contains cocaine, opiates, and some other meds. It is an evidenced based treatment for chronic pain, so please don't assume just because it has cocaine in it means it's gonna kill you. People suffering from chronic.pain need relief. if Brompton's works, then let them get their much needed relief!!! Without judgement!!

Reply

• From this study (3 weeks ago):

I was in three car accidents, one in which my head was turned and I got rear ended from behind that was when all the pain issues started along with the percocet prescription. I didn't intially use the script but later on in the years I started to develop alot more pain after being hit in two more whip lash car accidents in which my car was written off. I had a death of my parent only two months after the last accident and thats when I started to take more pain medication then prescribed. I have always had issues with my moods, I remember having a panic attack after a break-up with my long term boyfriend when I was 25 and going to a walk in clinic and them giving me effexor 75mg which worked great at that time, a little too great since I couldn't cry and eventually tried to overdose when the newest relationship I got myself involved in was to a married man and unhealthy. I kept off meds for sometime after that but found myself more stressed when I was 27 after my long term bf had an affair with my cousin and had two kids with her, I was left with a house in my name that was just bought 9 months prior and no job due to my pain issues. I started on wellbutrin 150xl then and virpo acid, which I didn't feel was working but looking back maybe it was. I have taken wellbturin more then 3 times since and everytime I Was very irritable and had to go off. I tried many other pills and I"m getting so fustrated. I really wish I had some answers, MY biggest complaint is that I"m always tired, which makes me depressed and in more pain. and then I find I'm abusing adderal or other stimulants to stay awake longer and then at night can't sleep. I was hospitalized and went through detox on my own in feb of this year. only to come out of the hospital on celexa 20mg and fight with the current bf over counserlling issues and break up and end up dating for 2 weeks a guy i met in hospital all in which time I relapsed. I am just a whits end. Please any advice would be great

Reply

Snood on May, 1, 2013:

1. No romantic relationships for six months to a year
2. Research the word "Codependent" and engage in some loving and gentle introspection.
3. Join a group called "CODA"

Reply

• From this study (4 weeks ago):

Although some of the adverse outcomes tend to wax and wane as my mood shifts with bipolar disorder, the bed wetting is of extreme urgency. I'm looking for answers more for the bed wetting but would be happy to find reasons for the others as well.

Reply

• From this study (1 month ago):

would like to know how morphine helps bipolar

Reply

shannon on Apr, 13, 2013:

Not sure exact mech. of action, however, could be to raise "Feel Good" endorphines and possibly keep you more at a "near but not fully" manic point, so to speak. I know a few with depression treated with morphine for that reason...it increases the available dopamine between the nerve cells called the synapsis, in turn, giving a feeling of "well being". This effct is opposite in some people...such as scizophrenics...it seems to make them more apt
to do stranger stuff and hallucinate. Im just a paramedic that researches stuff like this and no physician by a long shot...just picked it up after researching a patient I thought was lying to me about a depression treatment plan with narcotic medication....I had to find it out for myself and the above explanation is the guts of the study....hope it helps....I research alot of "cases" I transport to the hospital with good stories...

Reply

• From this study (1 month ago):

I am in recovery from alcohol and drugs, this year after 10 years of continuous sobriety, I believe that some of the scripts have a side effect of drug seeking behavior, ultimately I want to be narcotic free, and probably need to see a psychiatrist to get the anti psychotic right, worried about taking Paxil, Chantix, Buspar, all help with depression, but is that to much dopamine or serotonin, not sure which one, but couldn't that be too many different anti depressants in a day

Reply

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