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From FDA reports: drug interactions between Naropin, Marcaine Hydrochloride Preservative Free, Morphine Hydrochloride, Ephedrine Hydrochloride for a Female patient aged 32

This is a personalized study for a 32 year old female patient. The study is created by eHealthMe based on reports of 2 people who take the same drugs and have drug interactionsfrom FDA.

On Nov, 28, 2014: 2 people who reported to have interactions when taking Naropin, Marcaine Hydrochloride Preservative Free, Morphine Hydrochloride, Ephedrine Hydrochloride are studied

Trend of Naropin, Marcaine Hydrochloride Preservative Free, Morphine Hydrochloride, Ephedrine Hydrochloride's drug interactions, side effects, and effectiveness reports (2881610)

Information of the patient in this study:

Age: 32

Gender: female

Conditions: Epidural Anaesthesia, Spinal Anaesthesia, Blood Pressure Decreased

Drugs taking:
- Naropin: used for < 1 month
- Marcaine Hydrochloride Preservative Free: used for < 1 month
- Morphine Hydrochloride: used for < 1 month
- Morphine Hydrochloride: used for < 1 month
- Ephedrine Hydrochloride: used for < 1 month

Drug interactions have: Muscular Weakness, Sensory Disturbance

eHealthMe real world results:

Comparison with this patient's adverse outcomes among females aged 32 (±5):

InteractionNumber of reports
Muscular Weakness (muscle weakness)2 (100.00%)
Sensory Disturbance (sense disturbance)2 (100.00%)

Most common interactions experienced by females aged 32 (±5) in the use of Naropin, Marcaine Hydrochloride Preservative Free, Morphine Hydrochloride, Ephedrine Hydrochloride:

InteractionNumber of reports
Muscular Weakness (muscle weakness)2
Sensory Disturbance (sense disturbance)2
Drug Exposure During Pregnancy2
Blood Pressure Decreased (abnormally low blood pressure)2
Monoplegia (a paralysis of a single limb)2
Hypoaesthesia (reduced sense of touch or sensation)2

Most common interactions experienced by females aged 32 (±5) in long term use of Naropin, Marcaine Hydrochloride Preservative Free, Morphine Hydrochloride, Ephedrine Hydrochloride:

None.

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
Muscular Weakness (muscle weakness)2 (100.00%)
Sensory Disturbance (sense disturbance)2 (100.00%)

Most common interactions experienced by people in the use of Naropin, Marcaine Hydrochloride Preservative Free, Morphine Hydrochloride, Ephedrine Hydrochloride:

InteractionNumber of reports
Muscular Weakness (muscle weakness)2
Sensory Disturbance (sense disturbance)2
Drug Exposure During Pregnancy2
Blood Pressure Decreased (abnormally low blood pressure)2
Monoplegia (a paralysis of a single limb)2
Hypoaesthesia (reduced sense of touch or sensation)2

Most common interactions experienced by people in long term use of Naropin, Marcaine Hydrochloride Preservative Free, Morphine Hydrochloride, Ephedrine Hydrochloride:

None.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Comments from related studies:

  • From this study (4 weeks ago):

  • I have OCD but after I started Zonegram 50mg bd 3 days ago, I have noticed my anxiety getting increasingly worse and I had a severe panic attack yesterday. The Zonegram has also decreased the severe paranoia I feel with the ketamine but it has introduced some memory loss. Otherwise I feel the best I have in years. Should I swap my antidepressant to help with the anxiety?

    I recently came off Gabapentin (1800 tds --> 1200bd --> tapering down to nothing) and noticed my baseline pain level rising, hence the starting of the Zonegran.

    How can I be sure the the positive side effects of the Zonegran are not going to disappear once I leave hospital and stop the ketamine and morphine? Basically is what I'm feeling just a reaction of the Zonegran and ketamine or will the Zonegran continue to work in my favour (minus the anxiety and memory loss) once I leave hospital?

    I am in hospital now, I have entered hospital for Multiple Sclerosis neuropathic pain and am on these drugs to treat neuropathic pain but suspect I may also have Crohn's Disease/ulcerative colitis/irritable bowel syndrome hence the Neuropathic Pain and Abdominal Pain.

    Reply

  • From this study (4 weeks ago):

  • My legs have been swelling severely for months they checked my heart kidneys and blood pressure none of those things are causing this

    Reply

    justbeth on Nov, 23, 2014:

    How are your oxygen levels? My legs did that before I was diagnosed with COPD. Not that you need another ailment. You for sure don't need another medication.

    Reply

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Can you answer these questions (Ask a question):

More questions for: Blood Pressure Decreased, Epidural Anaesthesia, Marcaine Hydrochloride Preservative Free, Muscular Weakness, Naropin, Sensory Disturbance

You may be interested at these reviews (Write a review):

  • Nardil side effects and my experience taking it
    I have been on many SSRI AND SNRI medications that quickly became ineffective. Was told by a doctor friend that she had been on an MAOI inhibitor for many years with good results. After going thru a horrible withdrawal detox from the SNRI I had been on and then a period of no med at all I was started on Nardil, as I needed assistance from Pfizer, the many turner in affording the medicine. My friend was on Parnate, a different brand of an MAOI.
    Within days, not weeks I felt the depression lifting. It was the most dramatic and fastest response I had ever had to any antidepressant .
    Then the fainting started, falls with resulting broken ribs, bedridden and alone I lost over25 lbs in two weeks. I was of normal weight for my height. After I was able to function again, I noticed that my legs were very weak. We cut my dosage from 3 pills daily to 2. That seemed to have stopped the faint spells. However I still had/have low blood pressure that I monitor at home. My Systolic BP was usually in the 70's and 80's. One of the lowest was shocking to me. It was 52/27.
    My son is a hospital RN and said they would never discharge a patient with Bp that low.
    He was very worried about me as I live alone. I fainted twice after climbing the 13 stairs to my bedroom. The first fall was very bad as I was unconscious and my ribs were severely injured/fractured completely around the front and back and was in terrific pain. I took to my bed and did not seek medical attn. my last ambulance ride to the hospital a mile from my house cost $1000 and since I have no income or relatives/friends to call for help, I just lay in bed I awful pain that was woes when I tried to get out of bed. Thus I lost 25 lbs of muscle, since I had very little body fat.
    It has been two months since that fall and still have one area of pain in the front left ribs and a swollen spleen. The doctor gave me no additional meds and just said to give my body more time to heal. So once again was changed to 2 pills daily instead of 3. The hypotension and fainting got better. But I am now left with very weak legs and fall easily and frequently. Guess I lost a lot of muscle mass with the weight loss. However after a lifetime of depression, Nardil works wonderfully for that which had been long-standing and severe for so many years. People noticed the change in me shortly after starting the Nardil. But I am stubborn about going off it despite all the side effects because it works so much better than any of the many others I had been put on over the years.
    I am soon going to start doing leg exercises with ankle weights, starting with light weights are first and gradually increasing the weight as I hopefully rebuild my muscles and strength.
    Also my vision has gotten blurry and I feel slightly retarded after the weeks in bed when I was breathing very shallowly due to the broken ribs and my brain was deprived of adequate oxygen.
    Prior to all this I had an IQ of 140. If they tested me now, I know I would be way down from that. Also doing lung/breathing exercises to expand my lungs so I can take in more air with each breath.
    So that is my story of Nardil, hypotension, and depression. I had to really suffer to remain on this med that worked so magically for me after so many failures. It meant that much to me to not be crippled by depression.
  • Prostatitis and prostate cancer acceleration due to anaesthetics
    Caught Chlamydia in 1978. Interestingly, the partnered girl's sister worked in an aviary; and I found out later that Chlamydia originates from handling birdshit and birds are the carriers. Chlamydia was undiagnosed at the time, so it was listed under 'Non-specific urethritis'. Chlamydia wasn't named until about 8 years later. I was given tetracycline and told to stay off alcohol and sex. Yeah, really?

    I was 24; highly sexed, and in night clubs and pubs most nights. I laid off the alcohol and after two weeks, I was good. The laying off sex, I understood, because of contamination of others (condoms were little used in 1978 in the singles arena); so I masturbated one night... and that caused me immense in my prostate, and pain and suffering for the rest of my life.

    The ejaculation was extremely painful, and chronic prostatitis started. I was on and off medication for two years. I got light-sensitivity, which means in sunlight, I came out in burning rashes. I became allergic to tetracycline.

    The message? Consultants are generally poor at communicating what not to do, and why not. Lay off sex he said. All he had to say was no sex, no masturbation; or you may suffer for the rest of your life. That would have done it.

    No-one has been able to help me with this chronic prostatitis. In the early years it would come and go, but as the years have gone on, it has become more frequent, and now it is constant.

    Four years ago I went in for major foot surgery, and flat-lined. I was in intensive care for 2 days, on a morphine drip for the pain.
    When I awoke, I knew immediately I was suffering with my prostate. It was aching badly and I was urinating frequently. The nurses were amazed with how many 'bottles' I filled in such a short time.
    For the next few months, I was in agony. I have tried every possible drug going, as well as prostate massage and the indignancy of a urethragram whilst female students were watching.

    In November 2011 I went to see another consultant, who suggested a biopsy. I was diagnosed with prostate cancer. After much research, I now know that my diet and lifestyle, coupled with inflammation of the prostate with prostatitis, has caused prostate cancer. Yes, there is a direct relationship between prostatitis and prostate cancer.

    I am now beating it, without drugs and without surgery. I have changed my diet to a vegan diet, no sugar, very little alcohol, and a lot of supplementation.

    In December 2013, I went in for more foot surgery. I was unaware about the morphine at this time, so didn't consider it being a problem. I talk to the anaesthetist, who wanted me to have an epidural (injection in the spine to numb my lower body). At no point did he talk to me about my prostate history.
    In recovery, I sensed a problem as soon as the anaesthetic began to wear off. It was like my prostate and testicles wanted to explode. I knew I was going to have problems. My intuition reminded me of three years ago with the morphine, so I asked the surgeon if he knew of these complications with morphine, but he didn't.

    I spoke to the head of the post-operative ward and asked her if she had any experience of post-operative patients who suffered with prostatitis after surgery, and she confirmed she had. So here was a nurse who knew of the problems, but the surgeon and anaesthetist didn't. This is typical in the health service... the lack of sharing.

    Not only did I suffer with the chronic prostatitis (and still am 11 month later) I was incontinent. It took 6 months of 4-times daily legal exercises to get back control of my bladder.
    For me, morphine has a dire effect on my prostate.

    Bear in mind that your prostate is designed to eliminate toxins, so it is flooded with morphine. I will do my best to ensure I check for morphine in any drugs or anaesthetics in future.

    My first PSA level was 18, 3 ears ago. I brought it down to 13.5, then 10.4, 10.3, 10.9, 11.3, 14.3 and after the last surgery it spiked at 17.5. As a result, I have gone back to a stricter, greener raw diet to bring it down again.

    Oh, and anther tip; you need to get your vitamin D3 blood count above 200n/mols (UK measure) to have any chance of not getting prostate cancer. Mine was 32 when I was diagnosed. Today it is over 200, from supplementation of 10000 ius a day. Minimum in the UK, recommended by scientists, is 75n/mols, and it's too low. OK if you have a great immune system, but not if you want to fight prostate cancer and prostatitis.

    Black African males in the Northern US states and in Europe have twice as much risk, due to lack of sunlight. Sunlight on skin promotes vitamin D3, which is essential for the immune system and production of calcium.

    Black African males need more sunlight to produce the same amount of vitamin D3 as a caucasian male. Also, any male who is bald and fat has a higher risk, so a Black African, obese bald male, has an extremely high risk of prostate cancer, unless they get their immune system in order.

    The main way to fight all this, is on a clean, raw vegetable diet, pure water, no alcohol, sugar, processed or refined food, no meat, no dairy, no vegetable oil, no exceptions, and some breath-taking regular exercise. Just like we did 100 years ago. Go figure! Look at chronic disease studies of 100 years ago. 85% of all disease was from infection. Today 85% is from chronic disease.

    Your prostate eliminates toxins, and today, we are overloading it. Remove the toxins (and the stress and anxiety) and things will improve. It's a hard road; but with it is you want to be healthier and live longer.

    Good luck.
    Glenn.
  • Had nms in 2005, will trileptal increase chance of recurrence?
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.

More reviews for: Blood Pressure Decreased, Epidural Anaesthesia, Marcaine Hydrochloride Preservative Free, Muscular Weakness, Naropin, Sensory Disturbance

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