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What could cause Serotonin Syndrome, Acute brain syndrome, Acute confusional state, Delirium for a 45-year old woman who takes Opana Er, Lyrica, Levoxyl, Pristiq, Xanax, Ambien Cr, Percocet, Zanaflex?





Summary: 2 female patients aged 45 (±5) who take the same drugs are studied.

This is a personalized study for a 45 year old female patient who has Pain - Back, Fibromyalgia Syndrome, Hypothyroidism, Depression, Anxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, Tension, Insomnia Related To Another Mental Condition. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Opana er has active ingredients of oxymorphone hydrochloride. It is often used in pain. (latest outcomes from Opana er 1,455 users)

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from Lyrica 66,558 users)

Levoxyl has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. (latest outcomes from Levoxyl 15,715 users)

Pristiq has active ingredients of desvenlafaxine succinate. It is often used in depression. (latest outcomes from Pristiq 15,576 users)

Xanax has active ingredients of alprazolam. It is often used in stress and anxiety. (latest outcomes from Xanax 58,976 users)

Ambien cr has active ingredients of zolpidem tartrate. It is often used in insomnia. (latest outcomes from Ambien cr 3,166 users)

Percocet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. (latest outcomes from Percocet 26,450 users)

Zanaflex has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. (latest outcomes from Zanaflex 7,305 users)

What are the conditions

Pain - back can be treated by Percocet, Tramadol Hydrochloride, Hydrocodone Bitartrate And Acetaminophen, Vicodin, Flexeril, Norco. (latest reports from Pain - Back 6,132 patients)

Fibromyalgia syndrome (constant pain in their muscles and soft tissues) can be treated by Lyrica, Cymbalta, Savella, Gabapentin, Amitriptyline Hydrochloride, Neurontin. (latest reports from Fibromyalgia Syndrome 24,073 patients)

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) can be treated by Synthroid, Levothyroxine Sodium, Levoxyl, Levothyroxine Thyroid, Levothroid, Armour Thyroid. (latest reports from Hypothyroidism 43,269 patients)

Depression can be treated by Zoloft, Cymbalta, Prozac, Wellbutrin Xl, Celexa, Lexapro. (latest reports from Depression 254,062 patients)

Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension can be treated by Xanax, Klonopin, Clonazepam, Lexapro, Ativan, Lorazepam. (latest reports from Anxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, Tension 180,206 patients)

Insomnia related to another mental condition (sleeplessness related to another mental condition) can be treated by Trazodone Hydrochloride, Ambien, Zopiclone, Seroquel, Temazepam, Lunesta. (latest reports from Insomnia Related To Another Mental Condition 492 patients)

What are the symptoms

Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time) has been reported by people with depression, pain, stress and anxiety, major depression, bipolar disorder.(latest reports from Serotonin syndrome 6,516 patients)

Acute brain syndrome, acute confusional state, delirium (acute temporary reversible impairment of brain functioning) has been reported by people with depression, pain, high blood pressure, insomnia, herpes zoster.(latest reports from Acute brain syndrome, acute confusional state, delirium 14,554 patients)

On Nov, 21, 2014: 2 females aged 40 (±5) who take Opana Er, Lyrica, Levoxyl, Pristiq, Xanax, Ambien Cr, Percocet, Zanaflex are studied

Opana Er, Lyrica, Levoxyl, Pristiq, Xanax, Ambien Cr, Percocet, Zanaflex outcomes

Information of the patient in this study:

Age: 40

Gender: female

Conditions: Pain - Back, Fibromyalgia Syndrome, Hypothyroidism, Depression, Anxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, Tension, Insomnia Related To Another Mental Condition

Drugs taking:
- Opana Er - 20MG (oxymorphone hydrochloride): used for < 1 month
- Lyrica - 300MG (pregabalin): used for 6 - 12 months
- Levoxyl - 0.1MG (levothyroxine sodium): used for 1 - 2 years
- Pristiq (desvenlafaxine succinate): used for < 1 month
- Xanax - 1MG (alprazolam): used for 1 - 2 years
- Ambien Cr - 12.5MG (zolpidem tartrate): used for 1 - 2 years
- Percocet - 325MG;7.5MG (acetaminophen; oxycodone hydrochloride): used for 1 - 6 months
- Zanaflex - EQ 4MG BASE (tizanidine hydrochloride): used for 1 - 6 months

Drug interactions have: most severe serotonin syndrome, severe acute brain syndrome, acute confusional state, delirium

eHealthMe real world results:

Comparison with this patient's adverse outcomes:

InteractionNumber of reports on eHealthMe
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)2 (100.00% of females aged 40 (±5) who take the drugs)
Acute Brain Syndrome, Acute Confusional State, Delirium (acute temporary reversible impairment of brain functioning)2 (100.00% of females aged 40 (±5) who take the drugs)

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

Symptom (click a symptom for in-depth analysis)Number of reports on eHealthMe
Serotonin Syndrome in Pain - Back1 (0.14% of females aged 40 (±5) who have Pain - back)
Serotonin Syndrome in Fibromyalgia Syndrome31 (1.10% of females aged 40 (±5) who have Fibromyalgia syndrome)
Serotonin Syndrome in Hypothyroidism2 (0.06% of females aged 40 (±5) who have Hypothyroidism)
Serotonin Syndrome in Depression202 (1.03% of females aged 40 (±5) who have Depression)
Serotonin Syndrome in Anxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, Tension28 (0.33% of females aged 40 (±5) who have Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension)
Serotonin Syndrome in Insomnia Related To Another Mental Condition1 (0.65% of females aged 40 (±5) who have Insomnia related to another mental condition)
Acute Brain Syndrome, Acute Confusional State, Delirium in Pain - Back1 (0.14% of females aged 40 (±5) who have Pain - back)
Acute Brain Syndrome, Acute Confusional State, Delirium in Fibromyalgia Syndrome3 (0.11% of females aged 40 (±5) who have Fibromyalgia syndrome)
Acute Brain Syndrome, Acute Confusional State, Delirium in Hypothyroidism10 (0.28% of females aged 40 (±5) who have Hypothyroidism)
Acute Brain Syndrome, Acute Confusional State, Delirium in Depression35 (0.18% of females aged 40 (±5) who have Depression)
Acute Brain Syndrome, Acute Confusional State, Delirium in Anxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, Tension6 (0.07% of females aged 40 (±5) who have Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension)
Acute Brain Syndrome, Acute Confusional State, Delirium in Insomnia Related To Another Mental Condition1 (0.65% of females aged 40 (±5) who have Insomnia related to another mental condition)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Side effect (click a side effect for in-depth analysis)Number of reports on eHealthMe
Serotonin Syndrome in Opana Er2 (1.56% of females aged 40 (±5) who take Opana er)
Serotonin Syndrome in Lyrica5 (0.12% of females aged 40 (±5) who take Lyrica)
Serotonin Syndrome in Levoxyl2 (0.17% of females aged 40 (±5) who take Levoxyl)
Serotonin Syndrome in Pristiq11 (0.62% of females aged 40 (±5) who take Pristiq)
Serotonin Syndrome in Xanax12 (0.19% of females aged 40 (±5) who take Xanax)
Serotonin Syndrome in Ambien Cr1 (0.28% of females aged 40 (±5) who take Ambien cr)
Serotonin Syndrome in Percocet5 (0.19% of females aged 40 (±5) who take Percocet)
Serotonin Syndrome in Zanaflex4 (0.31% of females aged 40 (±5) who take Zanaflex)
Acute Brain Syndrome, Acute Confusional State, Delirium in Opana Er1 (0.78% of females aged 40 (±5) who take Opana er)
Acute Brain Syndrome, Acute Confusional State, Delirium in Lyrica11 (0.26% of females aged 40 (±5) who take Lyrica)
Acute Brain Syndrome, Acute Confusional State, Delirium in Levoxyl1 (0.08% of females aged 40 (±5) who take Levoxyl)
Acute Brain Syndrome, Acute Confusional State, Delirium in Pristiq1 (0.06% of females aged 40 (±5) who take Pristiq)
Acute Brain Syndrome, Acute Confusional State, Delirium in Xanax19 (0.30% of females aged 40 (±5) who take Xanax)
Acute Brain Syndrome, Acute Confusional State, Delirium in Ambien Cr1 (0.28% of females aged 40 (±5) who take Ambien cr)
Acute Brain Syndrome, Acute Confusional State, Delirium in Percocet4 (0.15% of females aged 40 (±5) who take Percocet)
Acute Brain Syndrome, Acute Confusional State, Delirium in Zanaflex8 (0.62% of females aged 40 (±5) who take Zanaflex)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Opana Er is effective0.00%
(0 of 1 people)
n/an/an/an/an/an/an/a
Lyrica is effectiven/an/a100.00%
(1 of 1 people)
n/an/an/an/an/a
Levoxyl is effectiven/an/an/a0.00%
(0 of 1 people)
n/an/an/an/a
Pristiq is effective0.00%
(0 of 1 people)
n/an/an/an/an/an/an/a
Xanax is effectiven/an/an/a100.00%
(1 of 1 people)
n/an/an/an/a
Ambien Cr is effectiven/an/an/a100.00%
(1 of 1 people)
n/an/an/an/a
Percocet is effectiven/a0.00%
(0 of 1 people)
n/an/an/an/an/an/a
Zanaflex is effectiven/a0.00%
(0 of 1 people)
n/an/an/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Acute Brain Syndrome, Acute Confusional State, Delirium (acute temporary reversible impairment of brain functioning)Acute Brain Syndrome, Acute Confusional State, Delirium (acute temporary reversible impairment of brain functioning)Acute Brain Syndrome, Acute Confusional State, Delirium (acute temporary reversible impairment of brain functioning)Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)n/an/an/aRenal Failure Acute (rapid kidney dysfunction)
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)Acute Brain Syndrome, Acute Confusional State, Delirium (acute temporary reversible impairment of brain functioning)Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Muscle Twitching
Confusional State

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

You are not alone! Join a related mobile support group:
- support group for people who have Anxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, Tension
- support group for people who have Depression
- support group for people who have Fibromyalgia Syndrome
- support group for people who have Hypothyroidism
- support group for people who have Insomnia Related To Another Mental Condition
- support group for people who have Pain - Back
- support group for people who have Acute Brain Syndrome, Acute Confusional State, Delirium
- support group for people who have Serotonin Syndrome
- support group for people who take Ambien Cr
- support group for people who take Levoxyl
- support group for people who take Lyrica
- support group for people who take Opana Er
- support group for people who take Percocet
- support group for people who take Pristiq
- support group for people who take Xanax
- support group for people who take Zanaflex

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