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What could cause Serotonin Syndrome, Acute brain syndrome, Acute confusional state, Delirium for a 45-year old woman?

This is a personalized study for a 45 year old female patient who has Pain - Back, Fibromyalgia Syndrome, Hypothyroidism, Depression, Anxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, Tension, Insomnia Related To Another Mental Condition. The study is created by eHealthMe based on reports of 2 female patients aged 45 (±5) who take the same drugs from FDA and social media.

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What are the drugs

Opana er (what 1,447 Opana Er users reported?) has active ingredients of oxymorphone hydrochloride. It is used in pain.

Lyrica (what 66,482 Lyrica users reported?) has active ingredients of pregabalin. It is used in fibromyalgia.

Levoxyl (what 15,709 Levoxyl users reported?) has active ingredients of levothyroxine sodium. It is used in hypothyroidism.

Pristiq (what 15,540 Pristiq users reported?) has active ingredients of desvenlafaxine succinate. It is used in depression.

Xanax (what 58,884 Xanax users reported?) has active ingredients of alprazolam. It is used in stress and anxiety.

Ambien cr (what 3,161 Ambien Cr users reported?) has active ingredients of zolpidem tartrate. It is used in insomnia.

Percocet (what 26,410 Percocet users reported?) has active ingredients of acetaminophen; oxycodone hydrochloride. It is used in pain.

Zanaflex (what 7,293 Zanaflex users reported?) has active ingredients of tizanidine hydrochloride. It is used in muscle spasms.

What are the conditions

Pain - back (what 6,697 Pain - Back patients reported?) can be treated by Percocet, Tramadol Hydrochloride, Hydrocodone Bitartrate And Acetaminophen, Vicodin, Flexeril, Norco.

Fibromyalgia syndrome (what 92,905 Fibromyalgia Syndrome patients reported?) can be treated by Lyrica, Cymbalta, Savella, Gabapentin, Amitriptyline Hydrochloride, Neurontin.

Hypothyroidism (what 129,627 Hypothyroidism patients reported?) can be treated by Synthroid, Levothyroxine Sodium, Levoxyl, Levothroid, Levothyroxine Thyroid, Armour Thyroid.

Depression (what 1,147,758 Depression patients reported?) can be treated by Zoloft, Cymbalta, Prozac, Lexapro, Celexa, Wellbutrin Xl.

Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension (what 1,284,569 Anxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, Tension patients reported?) can be treated by Xanax, Klonopin, Clonazepam, Lexapro, Lorazepam, Ativan.

Insomnia related to another mental condition (what 1,104 Insomnia Related To Another Mental Condition patients reported?) can be treated by Trazodone Hydrochloride, Ambien, Zopiclone, Seroquel, Temazepam, Ambien Cr.

What are the symptoms

Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time) (what 34,513 Serotonin Syndrome patients reported?) has been reported by people with depression, pain, stress and anxiety, major depression, bipolar disorder.

Acute Brain Syndrome, Acute Confusional State, Delirium (acute temporary reversible impairment of brain functioning) (what 87,060 Acute Brain Syndrome, Acute Confusional State, Delirium patients reported?) has been reported by people with depression, pain, high blood pressure, insomnia, herpes zoster.

On Aug, 16, 2014: 2 females aged 40 (±5) who take Opana Er, Lyrica, Levoxyl, Pristiq, Xanax, Ambien Cr, Percocet, Zanaflex are studied

Opana Er, Lyrica, Levoxyl, Pristiq, Xanax, Ambien Cr, Percocet, Zanaflex outcomes

Information of the patient in this study:

Age: 40

Gender: female

Conditions: Pain - Back, Fibromyalgia Syndrome, Hypothyroidism, Depression, Anxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, Tension, Insomnia Related To Another Mental Condition

Drugs taking:
- Opana Er - 20MG (oxymorphone hydrochloride): used for < 1 month
- Lyrica - 300MG (pregabalin): used for 6 - 12 months
- Levoxyl - 0.1MG (levothyroxine sodium): used for 1 - 2 years
- Pristiq (desvenlafaxine succinate): used for < 1 month
- Xanax - 1MG (alprazolam): used for 1 - 2 years
- Ambien Cr - 12.5MG (zolpidem tartrate): used for 1 - 2 years
- Percocet - 325MG;7.5MG (acetaminophen; oxycodone hydrochloride): used for 1 - 6 months
- Zanaflex - EQ 4MG BASE (tizanidine hydrochloride): used for 1 - 6 months

Drug interactions have: most severe serotonin syndrome, severe acute brain syndrome, acute confusional state, delirium

eHealthMe real world results:

Comparison with this patient's adverse outcomes:

InteractionNumber of reports on eHealthMe
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)2 (100.00% of females aged 40 (±5) who take the drugs)
Acute Brain Syndrome, Acute Confusional State, Delirium (acute temporary reversible impairment of brain functioning)2 (100.00% of females aged 40 (±5) who take the drugs)

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

Symptom (click a symptom for in-depth analysis)Number of reports on eHealthMe
Serotonin Syndrome in Pain - Back1 (0.15% of females aged 40 (±5) who have Pain - back)
Serotonin Syndrome in Fibromyalgia Syndrome31 (1.11% of females aged 40 (±5) who have Fibromyalgia syndrome)
Serotonin Syndrome in Hypothyroidism2 (0.06% of females aged 40 (±5) who have Hypothyroidism)
Serotonin Syndrome in Depression202 (1.04% of females aged 40 (±5) who have Depression)
Serotonin Syndrome in Anxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, Tension28 (0.33% of females aged 40 (±5) who have Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension)
Serotonin Syndrome in Insomnia Related To Another Mental Condition1 (0.66% of females aged 40 (±5) who have Insomnia related to another mental condition)
Acute Brain Syndrome, Acute Confusional State, Delirium in Pain - Back1 (0.15% of females aged 40 (±5) who have Pain - back)
Acute Brain Syndrome, Acute Confusional State, Delirium in Fibromyalgia Syndrome3 (0.11% of females aged 40 (±5) who have Fibromyalgia syndrome)
Acute Brain Syndrome, Acute Confusional State, Delirium in Hypothyroidism10 (0.28% of females aged 40 (±5) who have Hypothyroidism)
Acute Brain Syndrome, Acute Confusional State, Delirium in Depression35 (0.18% of females aged 40 (±5) who have Depression)
Acute Brain Syndrome, Acute Confusional State, Delirium in Anxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, Tension6 (0.07% of females aged 40 (±5) who have Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension)
Acute Brain Syndrome, Acute Confusional State, Delirium in Insomnia Related To Another Mental Condition1 (0.66% of females aged 40 (±5) who have Insomnia related to another mental condition)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Side effect (click a side effect for in-depth analysis)Number of reports on eHealthMe
Serotonin Syndrome in Opana Er2 (1.56% of females aged 40 (±5) who take Opana er)
Serotonin Syndrome in Lyrica5 (0.12% of females aged 40 (±5) who take Lyrica)
Serotonin Syndrome in Levoxyl2 (0.17% of females aged 40 (±5) who take Levoxyl)
Serotonin Syndrome in Pristiq11 (0.63% of females aged 40 (±5) who take Pristiq)
Serotonin Syndrome in Xanax12 (0.19% of females aged 40 (±5) who take Xanax)
Serotonin Syndrome in Ambien Cr1 (0.28% of females aged 40 (±5) who take Ambien cr)
Serotonin Syndrome in Percocet5 (0.19% of females aged 40 (±5) who take Percocet)
Serotonin Syndrome in Zanaflex4 (0.31% of females aged 40 (±5) who take Zanaflex)
Acute Brain Syndrome, Acute Confusional State, Delirium in Opana Er1 (0.78% of females aged 40 (±5) who take Opana er)
Acute Brain Syndrome, Acute Confusional State, Delirium in Lyrica11 (0.26% of females aged 40 (±5) who take Lyrica)
Acute Brain Syndrome, Acute Confusional State, Delirium in Levoxyl1 (0.08% of females aged 40 (±5) who take Levoxyl)
Acute Brain Syndrome, Acute Confusional State, Delirium in Pristiq1 (0.06% of females aged 40 (±5) who take Pristiq)
Acute Brain Syndrome, Acute Confusional State, Delirium in Xanax19 (0.30% of females aged 40 (±5) who take Xanax)
Acute Brain Syndrome, Acute Confusional State, Delirium in Ambien Cr1 (0.28% of females aged 40 (±5) who take Ambien cr)
Acute Brain Syndrome, Acute Confusional State, Delirium in Percocet4 (0.15% of females aged 40 (±5) who take Percocet)
Acute Brain Syndrome, Acute Confusional State, Delirium in Zanaflex8 (0.62% of females aged 40 (±5) who take Zanaflex)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Opana Er is effective0.00%
(0 of 1 people)
n/an/an/an/an/an/an/a
Lyrica is effectiven/an/a100.00%
(1 of 1 people)
n/an/an/an/an/a
Levoxyl is effectiven/an/an/a0.00%
(0 of 1 people)
n/an/an/an/a
Pristiq is effective0.00%
(0 of 1 people)
n/an/an/an/an/an/an/a
Xanax is effectiven/an/an/a100.00%
(1 of 1 people)
n/an/an/an/a
Ambien Cr is effectiven/an/an/a100.00%
(1 of 1 people)
n/an/an/an/a
Percocet is effectiven/a0.00%
(0 of 1 people)
n/an/an/an/an/an/a
Zanaflex is effectiven/a0.00%
(0 of 1 people)
n/an/an/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Acute Brain Syndrome, Acute Confusional State, DeliriumAcute Brain Syndrome, Acute Confusional State, DeliriumAcute Brain Syndrome, Acute Confusional State, DeliriumAcute Brain Syndrome, Acute Confusional State, Deliriumn/an/an/aRenal Failure Acute
Serotonin SyndromeSerotonin SyndromeSerotonin SyndromeSerotonin SyndromePneumonia Aspiration
Muscle Twitching
Confusional State

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Get connected! Join a mobile support group:
- group for people who have Anxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, Tension
- group for people who have Depression
- group for people who have Fibromyalgia Syndrome
- group for people who have Hypothyroidism
- group for people who have Insomnia Related To Another Mental Condition
- group for people who have Pain - Back
- group for people who have Acute Brain Syndrome, Acute Confusional State, Delirium
- group for people who have Serotonin Syndrome
- group for people who take Ambien Cr
- group for people who take Levoxyl
- group for people who take Lyrica
- group for people who take Opana Er
- group for people who take Percocet
- group for people who take Pristiq
- group for people who take Xanax
- group for people who take Zanaflex

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Related drug interaction studies:

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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