A study of drug interactions between Paxil, Paroxetine, Oxycodone And Acetaminophen, Xanax, Hydrochlorothiazide for a Female patient aged 60
This is a personalized study of Paxil, Paroxetine, Oxycodone And Acetaminophen, Xanax, Hydrochlorothiazide drug interactions for a 60 year old female patient. The study is created by eHealthMe based on 24 reports from FDA.
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What are the drugs
Paxil has active ingredients of paroxetine hydrochloride. It is used in depression, stress and anxiety, generalized anxiety disorder, obsessive-compulsive disorder, panic disorder, dysthymia.
Paroxetine has active ingredients of paroxetine hydrochloride.
Oxycodone and acetaminophen has active ingredients of acetaminophen; oxycodone hydrochloride. It is used in pain, back pain - low, pain in limb, surgery, pain in extremity, fibromyalgia.
Xanax has active ingredients of alprazolam. It is used in stress and anxiety, generalized anxiety disorder, panic disorder, insomnia, panic attack, sleep disorder.
Hydrochlorothiazide has active ingredients of hydrochlorothiazide. It is used in high blood pressure, fluid retention, swelling, foot, leg, and ankle swelling, diuretic effect, diuretic therapy.
On Apr, 19, 2013: 24 people who reported to have interactions when taking Paxil, Paroxetine, Oxycodone And Acetaminophen, Xanax, Hydrochlorothiazide are studied
Information of the patient in this study:
Age: 60
Gender: female
Conditions: Depression
Drugs taking:
- Paxil
- Paroxetine
- Oxycodone And Acetaminophen
- Xanax
- Hydrochlorothiazide
Drug interactions have: Nervousness
eHealthMe real world results:
For females aged 60 (±5):
Comparison with this patient's adverse outcomes:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports |
| Nervousness | 1 (50.00%) |
Most common interactions experienced by females aged 60 (±5) in the use of Paxil, Paroxetine, Oxycodone And Acetaminophen, Xanax, Hydrochlorothiazide:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Skin Odour Abnormal | 1 |
| 2 | Weight Decreased | 1 |
| 3 | Wound Secretion | 1 |
| 4 | Tooth Abscess | 1 |
| 5 | Scar | 1 |
| 6 | Nausea | 1 |
| 7 | Pain In Jaw | 1 |
| 8 | Osteomyelitis | 1 |
| 9 | Oral Cavity Fistula | 1 |
| 10 | Osteonecrosis Of Jaw | 1 |
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Most common interactions experienced by females aged 60 (±5) in long term use of Paxil, Paroxetine, Oxycodone And Acetaminophen, Xanax, Hydrochlorothiazide:
(click on each outcome to view in-depth analysis, incl. how people recovered)| None. |
For people in general (regardless of gender or age):
Comparison with this patient's adverse outcomes:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports |
| Nervousness | 2 (8.33%) |
Most common interactions experienced by people in the use of Paxil, Paroxetine, Oxycodone And Acetaminophen, Xanax, Hydrochlorothiazide:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Amnesia | 18 |
| 2 | Somnolence | 18 |
| 3 | Oedema Peripheral | 10 |
| 4 | Pain | 10 |
| 5 | Weight Increased | 9 |
| 6 | Fatigue | 9 |
| 7 | Drug Withdrawal Syndrome | 9 |
| 8 | Muscle Spasms | 9 |
| 9 | Drug Ineffective | 9 |
| 10 | Depression | 7 |
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Most common interactions experienced by people in long term use of Paxil, Paroxetine, Oxycodone And Acetaminophen, Xanax, Hydrochlorothiazide:
(click on each outcome to view in-depth analysis, incl. how people recovered)| None. |
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In-depth study of side effects (who have it, when it happens and how):
- Nervousness in Paxil (1,369 reports)
- Nervousness in Oxycodone And Acetaminophen (5 reports)
- Nervousness in Xanax (1,230 reports)
- Nervousness in Hydrochlorothiazide (472 reports)
Could it be a symptom from a condition:
Drug effectiveness in real world:
- Paxil for Depression reported by 470 people (updated 3 days ago)
Alternative drugs:
- Depression (144 drugs) (updated 3 days ago)
Related drug interactions:
- Hydrochlorothiazide and Xanax drug interactions (2,738 reports)
- Oxycodone And Acetaminophen and Hydrochlorothiazide drug interactions (1,437 reports)
- Oxycodone And Acetaminophen and Xanax drug interactions (3,864 reports)
- Oxycodone And Acetaminophen and Paxil drug interactions (1,412 reports)
- Paxil and Xanax drug interactions (6,073 reports)
Comments from related studies:
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would like to know if any of theses medicines interact with each other. and want to know if any of them cause neuropathy?
peanuts on Mar, 31, 2010:
my friend is suffering from rhumatory arthertis.and is currenty taking cocaine. oxy cotin,prestine, wellbutrim, predisone 10mg what side effects should she expect ?????
jimmy on Apr, 29, 2013:
Susan,
Finally, I'd been reading thru here and finnaly, what doctor in the U.S. still prescribes cocaine? LOL
jimmy on Apr, 29, 2013:
IF you donT see my other comments, Never take Cymbalta or anything containing same ingrediants or speeding thru the same side effects durring their enjoyable living advertizements!
Jmsrocks on Jul, 25, 2012:
Probably death. Cocain and opiates together = speed ball.
Hebe on Jul, 31, 2012:
I have had two close relatives on prednisone, and for both of them it alone can make them feel really speedy. Combined with cocaine and wellbutrin would probably make sleeping very difficult. As the previous commenter mentioned, combining oxys into this is probably a bit dangerous.
Patty O'Neill on Aug, 10, 2012:
The comments about death in combination with cocaine and opiates or any other drug is possible
depending on how much and the situation. Frightening people is not the key here. Basically any drug in combination with another could cause a major health problem as we are all very much not the same makeup. Cheers,
ken on Aug, 17, 2012:
If she continues with this type of treatment, its kinda scary in all reality. Why not see a doctor, that's where the healing may start.
Jackie on Apr, 30, 2013:
I am wondering if you were diagnosed because you had pain and found out you had a neurological message going on.... or just a process of elimination over the pain after you were taking your anti psychotic medication? I've been taking oxycone for my pain my back and neck disc issues um for about a year now, was having joint pain and stiffness all over my body the Dr put me on cymbalta and now three weeks later he put me on wellbutrin and I'm wondering about seratonin syndrome... I'm having muscle twitching also lump on top of my head and vision problems.
iCaNtCaLlIt on Oct, 24, 2012:
Please coke for arthrit.? take your fish oils 2 each meal and take your perscribed pain meds(careful very addicting) stop the coke thats being silly for real. goodluck, lifes a bych and ya die thats why we get high .. p.s ankle 9 surgerys plates screws never walk normal again, fight thru it..i got hurt at work btw 7 ton crushed my leg instead of me....jus always think thingd can be worse, be a gpod person dont let this bring u dwn n b miserable..pul thru keep head up n watch those pain meds..goodluck...email if u wana talk but dont come with negatibity. buhbye
susan on Jan, 3, 2013:
have vit d blood levles ck, and supplenment. vit d is an amazing pain control helper.
nefariouson3 on Nov, 7, 2012:
I too am a chronic pain sufferer, I drove over a explosive in the middle-east. I don't understand what or why this thread was written up like a true medical study, to me it looks more like a recreational train wreck, some listed drugs have reverse reactions and others simply have no medical need what so ever, personally I would seek professional help and attempt to get off the unneeded drugs and concentrate on the true medical issues. At your age 51, you run the risk of many complications and possibility death from the listed drugs, though who am I to judge, life is way too short enjoy it when your still alive.
Th3
Had'em all on Nov, 14, 2012:
Prison and/or death. Comparing taking coke by inhalation and oxycontin orally is NOT the same thing as speed ball. Kindergarten speed ball maybe. Addiction threshold of oxy is 60mg/day. She should try to stay below that.
Get her the hell off Pristine/Ketoconazole unless it is absolutely positively necessary. If necessary, try to get a lower dose. Stuff fries the liver & with all the other crap--BAD idea.
Is there a reason she isn't taking an NSAID? I see prednisone. Would help more than oxy.
kobe77 on Jan, 3, 2013:
Lmao! Lmao! You sound like your high ......enjoy your trip!
knowledgable on Jan, 7, 2013:
Death bed us what they should expect. Mixing cocaine and oxy, are they brainless!!!!
Sydney on Jan, 9, 2013:
Tell your friend to GET OFF WHEAT. The wheat products in this country are GMO which are very bad for us and cause arthritis. Tell your friend to research. Never let the Dr.s try and figure out what's wrong with you. They won't. And they'll kill you trying.
nursing101 on Jan, 28, 2013:
Well, NSAID, you say? Hmmm....I see motrin, naproxen and aspirin on the list....all NSAID's
Billy on Feb, 2, 2013:
It is a wonder that your wife is at all coherent taking that cocktail of medications. I would try to find a new doctor that has a better grasp of toxicology and drug interactions. Cocaine and Oxycotin--can't belief any reputable doctor would prescribe that combination.
High depression low motivation on Feb, 8, 2013:
I take fish oils and centrum vitamins for depression replacing latuda and Lexapro wich was messing with my school I was out of phase sleeping all day and cloudy thinking. Now I just take Adderall and Xanax for agoraphobia and I feel a lot better and Im actually doing homework!! I scored high on my test than on the antidepressants with low scores.
AdoreTu on Mar, 4, 2013:
Well, I just stopped at your post, and who ever is taking all of that stuff needs to take some Milk Thistle to help restore their liver.
Sam on Mar, 11, 2013:
Way back in the late 1960's I heard it called a combination of cocaine and opiate type drugs a speedball. My best guess is your friend is on the way out of this world, unless there is an intervention. In short, death is the end result/side effect of taking such a combination of drugs....
Deo Vindece,
Sam
BCS on Mar, 12, 2013:
Honestly. She can expect to die very young.
Everything from heart, kidney, liver, stomach, brain, lungs, immune system, etc. will began to shut down.
She will most likely become increasingly weak, finding herself in the hospital more often, and eventually die of organ failure. that is unless she dies from an overdoes first.
bcs on Mar, 12, 2013:
Yeah, hybrid wheat is causing all the problems. not the cocaine and oxy, mixed with other prescription drugs.
I agree Hybrid wheat is harmful and best left out of ones diet, but it's not the biggest problem here. (it hybrid not gmo) they haven't released that yet.
Susan on Mar, 12, 2013:
Are you guys really this dumb? She meant to say her friend was taking Codeine not cocaine. I'm not even going to bother asking a question on this website if you're that dumb! LOL
Jenn on Mar, 15, 2013:
I know that I am super sensitive to both codeine and oxy. They actually make me more nauseous and dizzy and i find regular tylenol or ibuprophen to be more effective against pain. I have heard some good things about omega fish oil and gluten free diets. My sister has RA too and when she flares up even pain meds dont help much. She is also gluten intolerant and can feel a marked difference in symptoms when she "slips" and eats gluten-y things. Steroids make your blood pressure high, she takes them when she gets flare ups but tries to ween herself off as the flare up dissipates. She gets weird skin breakouts because steroids also mess with the natural flora of your body. RA sux!!!!
doc moc on Mar, 25, 2013:
have tou tried cocaine? pretty sure its gluten free our previous inquisitor seemed to have some luck with its administration in combination with an assortment of other medications to treat her condition also as far as the flora issue goes i dont think cocaine is an antagonist
doc moc on Mar, 30, 2013:
oh yes BCS i agree hybrid wheat is a very dangerous substance especially when compared to the rather inocuous substances of cocaine and oxycontin! just what are your qualifications to dispense such well researched and supported opinions? You are truly a fool
Stephanie on Apr, 1, 2013:
Yeah I'm pretty sure she ment codeine. i dont visit these sites often anymore becasue my questions never get answered and everything gets way off topic.
really on Apr, 10, 2013:
people like you should visit your local humane society and have yourself spayed or neutered because the human race does not need less intelligent, human-jackass hybrid beings breeding with those of greater intellect. Cocaine was clearly written, not codeine. and please don't post your questions, prefer you be the guinea pig and take risks alerting the people who matter of potential risk factors. :)
Robert on Apr, 12, 2013:
I just wish the federal government would overhaul Richard Nixon's war on drugs and the whole controlled drug act. I have had my share of pain and you can consider yourself lucky to be able to cope with it. It is the sorry folk out there who have psychiatric disorders which affect the brain's ability to "deal" and cope, and is at a chemical level with them, a neurological mess-up. I know personally, I have phases of time when it is dangerous for me to try and tough it out when my brain sometimes slows down production and release of the natural chemicals like beta endorphin, dopamine, Gammaaminobuteric Acid, and I can find my body aches because Im not making enough natural opiate substances. SO I take drugs given by MD to make me feel normal, like clonazepam, prozac, and sometimes amphetamine in low doses. It is frustrating because people still don't understand and think I am a schmuck for taking drugs to feel normal happiness, calm, joy, relaxation, and to enjoy life's natural pleasures I periodically am unable to feel or appreciate.
Robert on Apr, 12, 2013:
It is true that speedballs, containing opiates and any stimulant. The "speed" in speedball likely refers to amphetamine, which was, prior to 1970, the original or at least most widely used upper in the 1960's. When the Controlled Drug Act was made official, cocaine became hugely popular, as an easier and more available alternative. SO strangely enough it became easier to get a totally outlawed drug than legal controlled drugs, because the new DEA and their most overzealous zealots were too busy finally settling old scores and getting the "dopeheads" and "speedfreeks" with the new Nixonian legislation backing them up like the word of God
Michele on Apr, 12, 2013:
I totally understand where you are coming from. Your comment at the end there helped me understand that I am not "a druggy" as my husband calls me because I need medications to feel an enjoy simple life activities. You're lucky to have found the right combination of medicines to treat your depression. I feel like I've been on a roller coaster for the last 20 years. If I find the "right" combination to treat my severe depression/bipolar2 disorders, then I find myself with one or more intolerable side effects that I must live with, like extreme teeth pain/bruxism. I look at people all the time and say to myself "That person is "normal." "That person is enjoying life." "That person sleeps normally and doesn't need help." "That person is a good mom for doing activities with her child/children." I get sorta jealous, then I start believing what my husband says about me being a druggy and that I am not a good teacher/mom/wife. That I shouldn't need medicine to just have energy to get up and get dressed. But when I read your post it made me feel good, not that you were dealing with depression, but that someone else out there understands how it feels, that my husband is dead wrong and out of line, that my depression is a real disorder and not my fault. Thank you for your post.
shannon on Apr, 13, 2013:
What shouldnt the expexation be...yes, cocaone is an antisthetic...only local, dentists "pink" mouth swab is cocaine based to numb the area and costrict blood vessels toz reduce swelling and bleeding....not for arthritis!..sounds like its a way to find a way out faster by destroying the heart muscle fro. The cocke's super stimulative effect and leave this world. There are other means to treat pain than death and mega doses of narcotics to mask the pain and increase the tolernance of the mds to the point that either there are no interior sinuses lrft by coke use or not enough pain meds to overcome the tolerance....ven IV cocaine use will burn the veins you shoot it in...its a loosing battle...and a painful one from damag thats beendone...Im praying for you guys...
Russ on May, 7, 2013:
Formally of you bashing the cocaine for pain, do some research! Brompton's Cocktail is a chronic pain medicine in liquid form that contains cocaine, opiates, and some other meds. It is an evidenced based treatment for chronic pain, so please don't assume just because it has cocaine in it means it's gonna kill you. People suffering from chronic.pain need relief. if Brompton's works, then let them get their much needed relief!!! Without judgement!!
high levels of medications found in blood work when taking how prescribed
I went to the hospital that I previously have had stroke/aneurysm coiling, active aneurysm in my neck. Have gone to same hospital when I had 3 TIA's. I have been taking Paxil and Xanax for 23 years. Could not find a PCP as I am a cash paying customer with no insurance. (My PCP retired.) Ran out of my medication (Paxil and Xanax), tried for a week to find new PCP to become established. No luck. After 5 days, I began vomiting and thinking suicidal thoughts (to me - normal for coming off 60 mg of Paxil in 5 days.) I explained to ER intake my symptoms and thoughts, told them I googled "Quick and Painless ways to die". She stopped listening as I also stated that I ALSO googled how long suicidal thoughts last after coming off Paxil cold turkey. I was there for HELP. What happened next is the most terrifying thing that has ever happened to me. I began a tirade that lasted hours. Using the most horrendous names you could think of... (Mel Gibson type tirade) at staff. Engaging them in aggressive behavior, calling names, spitting, screaming obscenities as loud as I could, thrusting my pelvis in the air, slapping it yelling that if they had to watch me then they were trying to watch my crotch and here it is... I AM NOT THIS KIND OF PERSON. Referring to an African American nurse as a mf'ing black, c*%k sucking whore, etc. They decided to restrain me. At this point, I begin to loose recollection of what happened. The last memory I have is that my boyfriend of 11 years KNEW something ELSE was wrong and he decided to take me to another hospital and he would NOT let me harm myself. NO! They called security, at our request, to help us out of there. They came and my boyfriend became aggressive with security. They asked if we wanted police. We said YES. I am convinced that they caused me to have a stroke. The last thing is screaming to my bf to go home, I loved him and did NOT want him in jail. I lay in that hospital, apparently until the next afternoon when they transported me to a mental institution. I have no recollection of leaving the hospital, the ambulance ride there. I slightly remember a couple of speed bumps going into facility. When I arrived the only thing I remember is ripping up paperwork when they told me where I was and crawling into bed. I vaguely remember them calling for meals but I gave an I'll be there in a minute, or I'll go to the next one answer. Apparently, I had been sleeping for three days. Remember being awakened to take pills but no one ever checked on me. I KNOW I HAD A STROKE. Is there any test to tell if a person has recently had a stroke?? Thank you very much.
After taking Pravastatin, Hydrochlorothiazide and Thiamine for less than one month have noticed that stool is pale. This was not the case prior to introducing these medications. Concerned about how liver might be affected.
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