Drug interactions between Klonopin, Seroquel, Phentermine Hydrochloride for a Male patient aged 41
This is a personalized study of Klonopin, Seroquel, Phentermine Hydrochloride drug interactions for a 41 year old male patient who has Depression, Lose weight. The study is created by eHealthMe based on 7 reports from FDA.
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What are the drugs
Klonopin has active ingredients of clonazepam. It is used in stress and anxiety, generalized anxiety disorder, panic disorder, insomnia, panic attack, restless leg syndrome.
Seroquel has active ingredients of quetiapine fumarate. It is used in bipolar disorder, insomnia, depression, bipolar i disorder, sleep disorder, stress and anxiety.
Phentermine hydrochloride has active ingredients of phentermine hydrochloride. It is used in weight loss, lipids abnormal, weight abnormal, obesity, appetite - decreased, exercise and weight loss.
On Apr, 16, 2013: 7 people who reported to have interactions when taking Klonopin, Seroquel, Phentermine Hydrochloride are studied

Information of the patient in this study:
Age: 38
Gender: male
Conditions: Depression, Lose weight
Drugs taking:
- Klonopin - 0.5MG (clonazepam): used for 1 - 6 months
- Seroquel - EQ 100MG BASE (quetiapine fumarate): used for < 1 month
- Phentermine Hydrochloride - 37.5MG (phentermine hydrochloride): used for < 1 month
eHealthMe real world results:
No reports for males aged 38 (±5) are found.
For people in general (regardless of gender or age):
Most common interactions experienced by people in the use of Klonopin, Seroquel, Phentermine Hydrochloride:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Diabetes Mellitus | 6 |
| 2 | Blood Cholesterol Increased | 5 |
| 3 | Road Traffic Accident | 2 |
| 4 | Attention Deficit/hyperactivity Disorder | 2 |
| 5 | Tearfulness | 2 |
| 6 | Sedation | 2 |
| 7 | Fatigue | 2 |
| 8 | Crying | 2 |
| 9 | Retching | 1 |
| 10 | Nausea | 1 |
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Most common interactions experienced by people in long term use of Klonopin, Seroquel, Phentermine Hydrochloride:
(click on each outcome to view in-depth analysis, incl. how people recovered)| None. |
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Related studies:
- Klonopin and Seroquel drug interactions (6,927 reports)
- Phentermine Hydrochloride and Seroquel drug interactions (70 reports)
- Phentermine Hydrochloride and Klonopin drug interactions (156 reports)
Drug effectiveness in real world:
- Klonopin for Depression reported by 22 people (updated 2 months ago)
- Seroquel for Depression reported by 116 people (updated 2 weeks ago)
- Phentermine Hydrochloride for Lose Weight reported by 725 people (updated 2 weeks ago)
Side effects in real world:
Browse all Klonopin side effects: 7,003 in total
Browse all Seroquel side effects: 7,418 in total
Browse all Phentermine hydrochloride side effects: 1,175 in total
Browse all Klonopin side effects: 7,003 in total
Browse all Seroquel side effects: 7,418 in total
Browse all Phentermine hydrochloride side effects: 1,175 in total
Alternative drugs:
- Depression (144 drugs) (updated 2 days ago)
- Lose Weight (57 drugs) (updated 6 hours ago)
Comments from related studies:
From this study (1 month ago):
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over the last 5 to 6 yrs I've been on these drugs and other anti-depressants. also was in the hospital for close to 3 months 6 plus yrs ago. In the last 3 yrs my dental issues have gone from minor to severe. To where I now have rapid tooth decay. The V.A. which i am a veteran, doesn't cover dental, but would cover dental if it was a result of other treatment. i.e, Clonazepam, creon, folic acid, about 2 yrs with them prescribing seroquel and trying different anti-depressants, like zoloft and zyprexa for short (1 to 3 months) periods of time. And was wondering if any of these drugs could be the cause of me having to now have my teeth pulled and getting dentures?
Robert on Apr, 12, 2013:
Zoloft is the most likely culprit, combined with clonazepam, together their similar oral side-effects combine in some cases causing oral and general dental problems. Zoloft's rather common side effect can be dry mouth.
Clonazepam has properties making it a potent anti-convulsive drug, which are known to cause dental problems in some. It has been the cause of minor gum-soreness and bleeding, and with zoloft theres an interaction, because without saiva present in the mouth as a barrier, dental problems such as receding gum line, bleeding gums and enamel wear, all work to accelerate normal tooth decay, ultimately.
These two meds have similarities that affect you and your mouth more than the average person. Nothing to worry about , there are dozens upon dozens of different benzos like clonazepam out there, ones with less potent anti seizure properties, and most docs don't even know much about them, yet they still make many of these rarely prescribed meds because of people just like you who could benefit from them.
Increased and worsening fatigue
I found out I have svt heart conditions and was wondering if any of these drugs have an effect or cause any problems with it or cause you to get svt?
Worried about Tardive Dyskinesia
over the last 5 to 6 yrs I've been on these drugs and other anti-depressants. also was in the hospital for close to 3 months 6 plus yrs ago. In the last 3 yrs my dental issues have gone from minor to severe. To where I now have rapid tooth decay. The V.A. which i am a veteran, doesn't cover dental, but would cover dental if it was a result of other treatment. i.e, Clonazepam,Oxycodone, creon, folic acid, about 2 yrs with them prescribing seroquel and trying different anti-depressants, like zoloft and zyprexa for short (1 to 3 months) periods of time. And was wondering if any of these drugs could be the cause of me having to now have my teeth pulled and getting dentures?
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Recent related drug checks on eHealthMe:
- A study of drug interactions between Seroquel, Diclofenac, Naproxen, Doxycycline, Amoxicillin, Fluconazole, Trazodone Hydrochloride, Clonazepam, Azithromycin, Buspirone Hcl, Gabapentin, Lorazepam, Lonox, Wellbutrin, Ambien, Lamictal, Paxil, Aldactazide, Vicodin, Effexor, Adipex, Synthroid, Prozac, Neurontin, Abilify, Ciproflaxacin for a patient with Mania, Sleep Disorder, Bipolar Disorder. The patient has Agitation, Torticollis, Tendonitis, Pneumonia, Mood Swings, Irritability, Haemoptysis, Gingivitis, Gastroenteritis, Exostosis, Diabetes Mellitus, Chest Discomfort, Cervical Cyst, Caffeine Consumption, Bipolar Disorder, Attention Deficit/hyperactivity Disorder
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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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