A study of drug interactions between Sertraline, Mirtazapine, Acetaminophen, Tranexamic Acid, Ibuprofen Tablets Bp 400mg

This is a real world study of Sertraline, Mirtazapine, Acetaminophen, Tranexamic Acid, Ibuprofen Tablets Bp 400mg drug interactions. The study is created by eHealthMe based on 8 reports from FDA.

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What are the drugs

Sertraline has active ingredients of sertraline hydrochloride. It is used in depression, stress and anxiety, generalized anxiety disorder, dysthymia, panic disorder, obsessive-compulsive disorder.

Mirtazapine has active ingredients of mirtazapine. It is used in depression, stress and anxiety, sleep disorder, insomnia, generalized anxiety disorder, depressed mood.

Acetaminophen has active ingredients of acetaminophen. It is used in pain, headache, fever, arthritis, cold symptoms, the flu.

Tranexamic acid has active ingredients of tranexamic acid. It is used in haemorrhage, menorrhagia, gastrointestinal haemorrhage, coughing up blood, preventive health care, nasopharyngitis.

Ibuprofen tablets bp 400mg has active ingredients of ibuprofen.

On Mar, 15, 2013: 8 people who reported to have interactions when taking Sertraline, Mirtazapine, Acetaminophen, Tranexamic Acid, Ibuprofen Tablets Bp 400mg are studied

Information of the patient in this study:

Conditions: Depression

Drugs taking:
- Sertraline: used for < 1 month
- Mirtazapine
- Acetaminophen
- Tranexamic Acid
- Ibuprofen Tablets Bp 400mg

Drug interactions have: Chest Discomfort, Dysphagia, Early Morning Awakening, Malaise, Muscle Spasms, Mydriasis, Pharyngolaryngeal Pain

eHealthMe real world results:

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

Most common interactions experienced by people in the use of Sertraline, Mirtazapine, Acetaminophen, Tranexamic Acid, Ibuprofen Tablets Bp 400mg:

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Most common interactions experienced by people in long term use of Sertraline, Mirtazapine, Acetaminophen, Tranexamic Acid, Ibuprofen Tablets Bp 400mg:

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Drug effectiveness in real world:

• Sertraline for Depression reported by 119 people (updated 1 day ago)

Alternative drugs:

• Depression (144 drugs) (updated 1 day ago)

Related drug interactions:

Comments from related studies:

• From this study (2 months ago):

I have chronic lower backpain and am on oxycodone immediate release 30mg prescription. I take 10 a day which is 300mg (they didn't have Immediate Release on the drop down menu so I used oxycontin on the form which is time released... as close as I could get for accuracy. Then I have 3 kids and a husband whom I love dearly however the past 3 months I have been severely depressed so my dr. put me on prozac and tegretol. I take zofran which is anti nausea probably 3 times a week for nausea due to the meds. 2 days ago my husband announced he was contemplating leaving me (after 6 years married, 7 years together) so I really plumeted depression wise... dr. gave me the zyprexa for "extreme depression" whatever that means... it just made me sleep 15 hrs. I then got up this morning had a pretty productive good day, decided to go out with a girlfriend for a movie cause i needed to get out. after the movie we stopped by her girlfriends house where everyone was doing coke. I haven't done coke since I was 20 years old 5 years ago!! With my husband no less! So I stay and pitch and do some coke (to clear my head... yah right) 1 gram later I go home with major nausea and migraine... so not thinking I take 8mg of zofran for nausea 800mg ibprofen 2 excedrin migraine 1000mg tylenol (this may seem like a lot to most however I am on high powered pain meds everyday for my damn back so if they don't kill a headache I have to take I high dose of tylenol ibprofen and caffeine to calm it down...it takes more than the average person. then I start thinking okay a 1 gram of coke over 5hrs. all my normal meds for the day time then i take all this crap to kick my migraine and nausea from the coke and now what the fuck is going to happen with all this in my system... NOT SMART!!!

Reply

ras51 on Mar, 21, 2013:

Hey there. I totally related to your problem. Without the coke though. I used to take 12 30mgs of oxycodone a day. I have been in two life threatening accidents. I have herniated discs in C6,C7&L4,L5,&S1. It sucks bad. I got to the point where they don't even work anymore. Of course people love to judge you. Even if they don't know what you been through. I just want to put this out there for you. Since your prescribed the 30's they have no half-life. Four hours tops then you have to take more. MS Contin works great as in last long but,you still need something for breakthrough pain control. See how your doctor feels about putting you on methadone. I know what people think about Methadone. It's not just for heroin addiction. It works great for pain
I hope you don't get offended. I'm just giving some of my thoughts on your situation. Take Care. Good Luck with everything. I know back pain is absolutely horrible. I lost the love of my life going through this shit
I didn't mean to ramble on so much. I just see a lot of similarities.

Reply

PJ3 on Mar, 2, 2013:

I hope you are ok. To have so much chemicals in your body is a real danger. Why not research additional medical exams for help for your back instead? Check out Mayo clinic or top research on methods to help you with your pain without putting so many drugs into your body. And please dont destroy your brain by using coke.

Reply

mark on Feb, 25, 2013:

Male age 38 - upper middle

To the patient with lower back problems:

Please have a neurologist check your GAD 65 levels immediately. I had exact same symptomology for 10 years, and the pain only became more horrific as time went on. You may have a rare disease
known as Stiff Person Syndrome. PLEASE do not let your physician off the hook on this one. The blood draw will have to be likely sent to the Mayo Clinic. It only strikes one in a million people. However, it is more prominent in females, than males. It also affects individuals with pre-existing autoimmune diseases like diabetes. However, one does not have to have a pre-existing condition to have SPS. It has a dramatic affect on moods and stimulus as well. It often goes undiagnosed for years with negative consequences. Good luck.

Reply

Maria on Feb, 23, 2013:

Get help immediately! If not for you, for those 3 precious children that need their Momma. Do whatever it takes. You are far too young to be in the situation that you are in. There are too many medical interventions available for back pain rather than be doomed to 10 Oxycodone a day. You have a much more severe problem than your back. It's in your brain and it's called addiction. This is a terminal illness and it will kill you if you don't get it under control.I should know. I have been there.It is by the Grace of God that someone hasn't just "found you", if you know what I mean. Find a good doctor that is "Suboxone prescribing qualified". Make the appointment and get into treatment.

Reply

bill on Feb, 5, 2013:

You're a sad excuse for a human! I hope your husband does leave you and takes your children with him. You are a disgusting human being and I hope you all the bad in the world!

Reply

Lily on Jan, 31, 2013:

Wow, a whole 5 years since snorting coke? Want a cookie for that accomplishment? You're pathetic. I also suffer from chronic back pain, as well as chronic pelvic pain and fibromyalgia. I can't get the help I need because of drug abusers like you. It's frustrating for those of us who are actually suffering in pain, that cannot get adequate pain control due to those who abuse narcotics, like yourself. If you have regular, frequent headaches, that aren't related to substance abuse, you should talk to your doctor, to find out what's causing them, and if there's a better medication for you to take. It doesn't matter that you're on high dose pain medication, you still shouldn't take that many pills at once, especially that combination, due to the amount of tylenol (acetaminophen) they contain. I know pain sucks and is debilitating, but in the long run, you'd be best served by trying to get off the narcotics, or at least tapering down to a lower dose. Is your doctor not at all concerned about the long term implications
of so taking so many narcotics? Remember also, that you're taking acetaminophen on a daily basis, at a relatively high dose, just from the narcotics. Too much acetaminophen can cause liver damage, leading to liver failure and possibly death. You should ask your doctor about this, and about any ways to manage your pain without the narcotics (prescription anti-inflammatories, exercise, physical therapy, etc.). What would happen if your current dose no longer helps with the pain? It happens, as your body gets used to narcotics, you'll eventually require a higher dose for adequate pain relief. I'm sure that's been the case already, as you didn't just start out on 10 pills a day. If you're doctor isn't concerned about any of this, he's honestly not looking out for your best interest, he's just pushing pills at you. But maybe that's what you want anyhow.

Reply

jâne on Dec, 21, 2012:

if you have headache besides your lower back pain you should see if you have à csf leak and intracranial hypotension
if it is the case coke won t help you

Reply

Jared on Nov, 21, 2012:

Wow - I hope that you survived your night!!!! My only recommendation is to wean yourself off of all the pills that your Doc has you on, and really try to get off the OxyContin, as this will just slowly destroy you. Focus on reducing your inflammation naturally with Ginger tea, vitamins and other inflammation-reducing herbals. Go see a physiotherapist and look for either Prolotherapy or IMS. Is your back pain from an accident?

Cheers,

Jared

Reply

• From this study (2 months ago):

immediate pain on injection side after injection, pain up back and down leg wihin 15 minutes, pain on entire left side after 24 hours, tingling and pain in arm and leg injection side only after 48 hours, complete loss of sensation on left side, pain, muscle weakness, and not able to walk or use left side limbs after 72 hours and was admitted in hospital for 4 days of testing all tests came back pretty much normal. neurologist after released said everything was normal with nerve and muscles on left side, yet no change. I use a wheelchair when going out now, with assistance from spouse.

Reply

• From this study (3 months ago):

eosinophilia bowel problems with pain lethargic

Reply

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