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From FDA reports: drug interactions between Niaspan, Simvastatin, Lisinopril, Metoprolol Tartrate for a Male patient aged 66

This is a personalized study for a 66 year old male patient. The study is created by eHealthMe based on reports of 133 people who take the same drugs and have drug interactionsfrom FDA.

On Sep, 17, 2014: 133 people who reported to have interactions when taking Niaspan, Simvastatin, Lisinopril, Metoprolol Tartrate are studied

Trend of Niaspan, Simvastatin, Lisinopril, Metoprolol Tartrate's drug interactions, side effects, and effectiveness reports (3260927)

Information of the patient in this study:

Age: 66

Gender: male

Conditions: High Density Lipoprotein Decreased, Blood Cholesterol Increased, Hypertension

Drugs taking:
- Niaspan
- Niaspan: used for < 1 month
- Simvastatin
- Lisinopril
- Metoprolol Tartrate

Drug interactions have: Flushing, Drug Ineffective, Dizziness, Diabetes Mellitus

eHealthMe real world results:

Comparison with this patient's adverse outcomes among males aged 66 (±5):

InteractionNumber of reports
Flushing (the warm, red condition of human skin)24 (68.57%)
Drug Ineffective4 (11.43%)
Dizziness14 (40.00%)
Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)4 (11.43%)

Most common interactions experienced by males aged 66 (±5) in the use of Niaspan, Simvastatin, Lisinopril, Metoprolol Tartrate:

InteractionNumber of reports
Flushing (the warm, red condition of human skin)24
Pruritus (severe itching of the skin)16
Dizziness14
Hepatotoxicity (chemical-driven liver damage)12
Nausea (feeling of having an urge to vomit)12
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)12
Cholestatic Liver Injury (due to injury bile cannot floe from liver)10
Pain10
Renal Tubular Necrosis (death of kidney tubules)8
Renal Failure Acute (rapid kidney dysfunction)8

Most common interactions experienced by males aged 66 (±5) in long term use of Niaspan, Simvastatin, Lisinopril, Metoprolol Tartrate:

InteractionNumber of reports
Fall3
Pruritus (severe itching of the skin)3
Syncope (loss of consciousness with an inability to maintain postural tone)3
Rib Fracture3
Dizziness3
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)2
Pain2
Vomiting2
Transaminases Increased2
Vascular Operation2

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
Flushing (the warm, red condition of human skin)128 (96.24%)
Drug Ineffective12 (9.02%)
Dizziness38 (28.57%)
Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)12 (9.02%)

Most common interactions experienced by people in the use of Niaspan, Simvastatin, Lisinopril, Metoprolol Tartrate:

InteractionNumber of reports
Flushing (the warm, red condition of human skin)128
Pruritus (severe itching of the skin)56
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)48
Nausea (feeling of having an urge to vomit)44
Pain40
Dizziness38
Feeling Hot34
Chest Pain33
Fatigue (feeling of tiredness)25
Diarrhoea24

Most common interactions experienced by people in long term use of Niaspan, Simvastatin, Lisinopril, Metoprolol Tartrate:

InteractionNumber of reports
Dizziness4
Syncope (loss of consciousness with an inability to maintain postural tone)4
Pruritus (severe itching of the skin)4
Rib Fracture4
Fall4
Flushing (the warm, red condition of human skin)4
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)2
Transaminases Increased2
Vomiting2
Vascular Operation2

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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