What could cause Tonic Seizures for a 35-year old man who takes Trileptal, Flexeril?
Summary: 5 male patients aged 35 (±5) who take the same drugs are studied.
This is a personalized study for a 35 year old male patient who has Epilepsy, Pulled muscle. The study is created by eHealthMe based on reports from FDA and social media.
What are the drugs
Trileptal has active ingredients of oxcarbazepine. It is often used in epilepsy. (latest outcomes from Trileptal 11,884 users)
Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. (latest outcomes from Flexeril 16,445 users)
What are the conditions
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures) can be treated by Lamictal, Keppra, Dilantin, Tegretol, Lamotrigine, Carbamazepine. (latest reports from Epilepsy 37,206 patients)
Pulled muscle (an injury to a muscle or tendon in which the muscle fibres tear as a result of overstretching) can be treated by Flexeril. (latest reports from Pulled Muscle 52 patients)
What is the symptom
Tonic seizures (all the muscles to suddenly become stiff) has been reported by people with epilepsy, seizures, generalized anxiety disorder, depression, high blood cholesterol.(latest reports from Tonic seizures 320 patients)
On Dec, 15, 2014: 5 males aged 30 (±5) who take Trileptal, Flexeril are studied
Information of the patient in this study:
Conditions: Epilepsy, Pulled muscle
- Trileptal - 600MG (oxcarbazepine): used for 10+ years
- Flexeril - 10MG (cyclobenzaprine hydrochloride)
Drug interactions have: moderate tonic seizures
eHealthMe real world results:
Comparison with this patient's adverse outcomes:
|Interaction||Number of reports on eHealthMe|
|Tonic Seizures (all the muscles to suddenly become stiff)||2 (40.00% of males aged 30 (±5) who take the drugs)|
(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)
|Symptom (click a symptom for in-depth analysis)||Number of reports on eHealthMe|
|Tonic Seizures in Epilepsy||1 (0.07% of males aged 30 (±5) who have Epilepsy)|
|Tonic Seizures in Pulled Muscle||1 (20.00% of males aged 30 (±5) who have Pulled muscle)|
(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)
|Side effect (click a side effect for in-depth analysis)||Number of reports on eHealthMe|
|Tonic Seizures in Trileptal||1 (0.22% of males aged 30 (±5) who take Trileptal)|
|Tonic Seizures in Flexeril||1 (0.25% of males aged 30 (±5) who take Flexeril)|
Drug effectiveness over time :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Trileptal is effective||n/a||n/a||n/a||n/a||n/a||n/a||100.00%|
(1 of 1 people)
|Flexeril is effective||n/a||n/a||n/a||n/a||n/a||n/a||n/a||0.00% |
(0 of 1 people)
Most common drug interactions over time * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|n/a||n/a||n/a||n/a||n/a||n/a||Tonic Seizures (all the muscles to suddenly become stiff)||Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)|
|Gastritis (inflammation of stomach)|
|Rash Papular (redness with papule)|
|Pancreatitis (inflammation of pancreas)|
|Type 2 Diabetes Mellitus|
|Ulcer (stomach ulcer)|
|Pancreatitis Acute (sudden inflammation of pancreas)|
|Blood Pressure Decreased (abnormally low blood pressure)|
|Rash Pruritic (redness with itching)|
* Some reports may have incomplete information.
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You are not alone! Join a related mobile support group:
- support group for people who take Trileptal and have Tonic Seizures
- support group for people who take Flexeril and have Tonic Seizures
- support group for people who have Tonic Seizures and Epilepsy
- support group for people who have Tonic Seizures and Pulled muscle
- support group for people who have Epilepsy
- support group for people who have Pulled Muscle
- support group for people who have Tonic Seizures
- support group for people who take Flexeril
- support group for people who take Trileptal
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In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.
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Comments from related studies:
From this study (2 years ago):
From this study (2 years ago):
From this study (3 years ago):
Since i've started the doxepin i have had headaches that last 2-5 days as severe as migraines to just a regular headache. sometimes they come and go throughout the day for 2-5 days, other times they have been persistent. also the longer i have been on the doxepin the more intolerance i have become to refined sugars. i get dizzy and disoriented when i eat them so severly i feel like i am going to pass out.
Im not sure if using Flexeril will affect my other medications. Please let me know if I need to stop.
Related drug interaction studies:
- Flexeril and Trileptal drug interactions (188 reports)
Drug effectiveness in real world:
- Trileptal for Epilepsy reported by 91 people (updated 2 days ago)
- Flexeril for Pulled Muscle reported by 7 people (updated 2 weeks ago)
Complete drug side effects:
Drugs associated with:
Conditions associated with:
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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