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What could cause Irritability for a 60-year old man who takes Wellbutrin, Advil Pm?





Summary: 6 male patients aged 60 (±5) who take the same drugs are studied.

This is a personalized study for a 60 year old male patient who has Anxiety Disorder, Sleeplessness. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (view latest outcomes from 54,972 users)

Advil pm has active ingredients of diphenhydramine hydrochloride; ibuprofen. It is often used in insomnia. (latest outcomes from Advil pm 226 users)

What are the conditions

Anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry) can be treated by Xanax, Klonopin, Clonazepam, Zoloft, Lexapro, Ativan. (latest reports from Anxiety Disorder 10,324 patients)

Sleeplessness (a sleep disorder in which there is an inability to fall asleep or to stay asleep as long as desired) can be treated by Ambien, Trazodone Hydrochloride, Lunesta, Zolpidem Tartrate, Ambien Cr, Zopiclone. (latest reports from Sleeplessness 131,086 patients)

What is the symptom

Irritability has been reported by people with depression, quit smoking, pain, stress and anxiety, attention deficit hyperactivity disorder.(latest reports from Irritability 23,359 patients)

On Nov, 30, 2014: 6 males aged 55 (±5) who take Wellbutrin, Advil Pm are studied

Wellbutrin, Advil Pm outcomes

Information of the patient in this study:

Age: 55

Gender: male

Conditions: Anxiety Disorder, Sleeplessness

Drugs taking:
- Wellbutrin (bupropion hydrochloride): used for 1 - 6 months
- Advil Pm (diphenhydramine hydrochloride; ibuprofen): used for < 1 month

Drug interactions have: severe irritability

eHealthMe real world results:

Comparison with this patient's adverse outcomes:

InteractionNumber of reports on eHealthMe
Irritability2 (33.33% of males aged 55 (±5) who take the drugs)

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

Symptom (click a symptom for in-depth analysis)Number of reports on eHealthMe
Irritability in Anxiety Disorder6 (0.90% of males aged 55 (±5) who have Anxiety disorder)
Irritability in Sleeplessness23 (0.71% of males aged 55 (±5) who have Sleeplessness)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Side effect (click a side effect for in-depth analysis)Number of reports on eHealthMe
Irritability in Wellbutrin38 (1.13% of males aged 55 (±5) who take Wellbutrin)
Irritability in Advil Pm1 (20.00% of males aged 55 (±5) who take Advil pm)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Wellbutrin is effectiven/a0.00%
(0 of 1 people)
n/an/an/an/an/an/a
Advil Pm is effective0.00%
(0 of 1 people)
n/an/an/an/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
IrritabilityIrritabilityn/an/an/an/an/aHypotension (abnormally low blood pressure)
Headache (pain in head)
Death
Insomnia (sleeplessness)
Renal Failure Acute (rapid kidney dysfunction)
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour)
Anxiety
Blood Urine Present
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
Pneumonia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

You are not alone! Join a related mobile support group:
- support group for people who take Wellbutrin and have Irritability
- support group for people who take Advil Pm and have Irritability
- support group for people who have Irritability and Anxiety Disorder
- support group for people who have Irritability and Sleeplessness
- support group for people who have Anxiety Disorder
- support group for people who have Sleeplessness
- support group for people who have Irritability
- support group for people who take Advil Pm
- support group for people who take Wellbutrin

Can you answer these questions (Ask a question):

  • I am on 2 x daily rifampin and 4 x daily cephalixin 500mg and and awake exhausted after 8-9 hours sleep and the fatigue is unbelievable all day every day, is this "normal" or should i investigate ore (1 answer)
    Had total knee replacement 11/12, bad from the start, knee swollen/hot/painful/unstable for most of 2 years before a mechanically successful Revision that found a loose patella and both ends of the prostheses loose. In spite of 10-12 aspirations and almost as many samples sent to labs for testing the result was always "no growth after a week". Following the revision, 10 days after, surgeons office called and says yes you have a staph E infection. Immediate therapy with 6 weeks of 3 X day IV PLUS 2 x per day oral Rifampin.
    IV over but now on the 2 X day Rifampin PLUS 4 X day 500mg cephalexin and the fatigue is unbelievable. Wake up exhausted after 8 hours sleep, daily hour plus mid afternoon naps.
  • Any information on deaths from taking lyica and high doses of alprazolam (1 answer)
    My Mother was a healthy 89 yr old with no healt issues, she was put on anxiety medicine, which she took regularly. She was also taking Lyric and had just started her Macular degeneration shots. She was prone to bladder infections and we went to the dr. for that, labs showed high calcium, within one week I had to take her to the emergency room, within one day she was on oxygen, within three days she was in the ICU intubated and unresponsive. She remained in ICU for 4 days had renal failure and died two days later.
  • I'm on two meds, can librium and diclofenac sodium be taken at the same time
    Trying too find out if I can safely take these two drugs together at the same time , or just take them times apart in the same day. Or don't take them together at all?
  • Can nuvigil (vs adderall) be used simultaneously to help wean off 60mg/day of adderall? (1 answer)
    I have been on Adderall 30mg 2x daily for years!! I've had it lowered to 20mg, I've TRIED to go months without it (when not working) however I feel I've built up a tolerance level to the point that it's not as effective as it once was. My personal life has detoured WAY past anything an ADHD medication can possibly help as far as focusing on NEEDED tasks etc. I end up feeling wrapped up in what I'm doing at the moment that my anxiety increases due to all that I haven't been able to accomplish. I take various medications for various reasons, depression, anxiety, bulimia etc., and for the most part the doses have varied based on circumstances and current need at said time of prescription.. MY FAMILY HAS A HISTORY OF HEART DISEASE, And realizing that I'm already on the highest Adderall dosage scares me (and THEN as I think about it, it makes my heart race!). I've also noticed increased muscle spasms as well as extreme and intense pressure on my jaw (TMJ). MY QUESTION IS: does anyone have any experience LOWERING their Adderall dosage AND adding Nuvigil? The research I've done to date gives me impression that it could help balance out the more extreme effects of Adderall (60mg/day) but that the nuvigil would or could potentially help with the EXTREME exhaustion I feel as Adderall wears off. Some days I just crash, some days I sleep fine and others no matter how hard I tryyyy, I just CAN'T fall asleep, therefore making the next day worse! IDEALLY I'D LIKE TO BE MED FREE, right now I need them, but am hoping maybe I can speak with my doctor to lower Adderall and add Nuvigil to help wean me off the amphetamines as well as lower dosage intake. YES, a lot of the anxiety, sleeplessness and depression are related to current circumstances in my life, however, where I am is not where I want to be or where I'm headed.. Life is a journey, and all my meds have become a part of a journey I never thought I'd find myself taking. I don't want life/meds to define me, or create a me I no longer recognize, because scarily enough that seems to be a common pattern. As I overcome each and every daily obstacle, I also don't want to be "hooked" on my meds or needing "more" to wake up/sleep/function.. I'd like to work on finding a solution towards weaning off my meds NOW, and work my way off slowly, primarily the Adderall. I'm hoping by suggesting to my doctor and showing him my research he may agree (IF ITS EVEN A LOGICAL COMBO, CLEARLY IM NOT A DOCTOR) nuvigil could help me. I've already started taking less of my anti depressants, trazadone and xanax without discussing with doc because he is always busy.. My next appt I want to go in fully prepared with a plan and an overall goal to REDUCE my Adderall dose, but overall, I'm clueless!!! I have no idea what other meds other than nuvigil "could" potentially help if at all. I could be entirely wrong, Anyone with any experience using one vs other or both simultaneously, or anyone with constructive input, PLEASE COMMENT/SHARE!!
  • What can i do to help my wife who is on ambien and sometimes has horrible restless leg syndrome?
    She will take her meds like a hour and a half before actually going to sleep. The Zambian that is and sometimes she has uncontrolled restless leg syndrome. She has to move them a certain way and everything. This last time it lasted a hour and a half. I was just wondering if there is anything I could do to belp.?

More questions for: Advil Pm, Anxiety Disorder, Irritability, Sleeplessness, Wellbutrin

You may be interested at these reviews (Write a review):

  • Intrsoccular pressure increase associated with wellbutrin
    I was given a prescription for Wellbutrin in approximately 1998. I had has my ocular pressure checked a year prior to this and it was okay. At the time, I only needed to wear reading glasses, common in people over 45. I took the drug at the full prescribed dosage for two weeks. Immediately prior to the narrow angle glaucoma episode, my vision had actually seemed to improve. For one day, prior, I could read without reading glasses. The following night, I was watching tv, and things suddenly became foggy. It was actually as if a fog had enveloped the room. I could not see anything except to discern between light and dark areas. I had to have emergency laser surgery the next morning. I mentioned to the doctor that Iwas taking Wellbutrin to stop smoking, and asked if it could have caused the ocular pressure increase. he consulted the PDR, and said there was no mention of it causing increases in ocular pressure. One year later my primary care doctor again insisted that I stop smoking, and again I mentioned that I thought it might increase ocular pressure. She told me to take a half dose, I did, and I took it one week, at which time I again experienced another episode of narrow angle glaucoma. When I go to the doctor's office my pressure in my left eye was 72, and 68 in my right eye. I was then referred on a triage basis to another doctor. I spent the rest of the day in his office having drops administered every fifteen minutes(extremely painful). I had extensive laser surgery the next morning.It required over fifty shots from the laser machine into each eye, (also extremely painful). I had lost considerable peripheral AND CENTRAL VISION in my left eye, and a good deal in my right. As a result of having to have such extensive laser surgery I also had cataracts that began at 50% maturity. I was advised by the surgeon that I should wait to have the cataracts removed "until my vision and quality of life was so poor that I was ready to commit suicide" because having the cataracts removed would cause the pressure in my eyes to become very difficult to control, and that more than likely I would end up being black blind. I would never use Wellbutrin under any circumstances, and I always check to make sure that any new meds I may be put on don't have anything to do with an increase in ocular pressure. If they do, I refuse to take them. The surgeon said he was surprised that I didn't lose more vision than I did, and I am grateful that I didn't, and that he was a good surgen. He wrote an article concerning this case for a medical journal since he said he had been seeing a recent increase of narrow angle glaucoma.
  • Librium 25mg and wellbutrin 300mg for >1 month
    I've been taking librium twice daily, morning and night, for about 3 months now along with wellbutrin XL in the morning. I've basically had the mood of "I don't care" and a great boost in confidence.
  • Doxylamine succinate and severe restless legs and insomnia
    Could not sleep so took 2 doxylamine gel tablets. Got very sleepy but could not actually fall asleep. So I ended up, over the next few hours, taking 3 more. More sleepiness and more restless legs, and still couldn't sleep At All. Up the entire night but couldn't really do anything cause I was so sleepy. Maddening. Do not understand at all.
  • Bedwetting with paxil and wellbutrin
    I have been using both of these drugs and now have bedwetting issues 5 times a week on average. I would rate the bedwetting as moderate about a6/10 but my wife and I can live with this as she had made the comment " you are back to the man I married ". I started taking these due to depression about work and anxiety about work. We both think we can live with the bedwetting as no one needs to know about it
  • Wellbutrin caused my trigeminal neurlagia
    So I'm writing this to hopefully shed light to other users in the same position I was in. I had taken Wellbutrin for about 4 years. The pain experienced in my face was excruciatingly painful. It was just on one side of my face between my temple and upper lip. All the symptoms reflected Trigeminal Neuralgia. But even with an MRI nothing could be found. I suffered for 3 of those years with pain coming and going, not understanding what was going on. Finally one day I decided hell with Wellbutrin and just stopped taking it. It's been 6 months now and I have yet to have a single shred of pain. Coincidence? I doubt it.

More reviews for: Advil Pm, Anxiety Disorder, Irritability, Sleeplessness, Wellbutrin

Comments from related studies:

  • From this study (3 years ago):

  • Been having alot of anxiety and high blood pressure. Worried that I'm taking so much medication!

    Reply

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Drug effectiveness in real world:

In-depth study of side effects (who have it, when it happens and how):

In-depth study of symptoms:

Complete drug side effects:

Alternative drugs:

Drugs associated with:

Conditions associated with:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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