Drug interactions between Wellbutrin, Advil Pm for a Male patient aged 59
This is a personalized study of Wellbutrin, Advil Pm drug interactions for a 59 year old male patient who has Anxiety Disorder, Sleeplessness. The study is created by eHealthMe based on 195 reports from FDA.
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What are the drugs
Wellbutrin has active ingredients of bupropion hydrochloride. It is used in depression, stress and anxiety, quit smoking, dysthymia, depressed mood, major depression.
Advil pm has active ingredients of diphenhydramine hydrochloride; ibuprofen. It is used in insomnia, pain, headache, natural short sleeper, sleep disorder, drowsiness.
On Apr, 17, 2013: 195 people who reported to have interactions when taking Wellbutrin, Advil Pm are studied

Information of the patient in this study:
Age: 55
Gender: male
Conditions: Anxiety Disorder, Sleeplessness
Drugs taking:
- Wellbutrin (bupropion hydrochloride): used for 1 - 6 months
- Advil Pm (diphenhydramine hydrochloride; ibuprofen): used for < 1 month
Drug interactions have: severe irritability
eHealthMe real world results:
For males aged 55 (±5):
Comparison with this patient's adverse outcomes:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports among males aged 55 (±5) who take the drugs |
| Irritability | 0 (0.00%) |
(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)
| Symptom | Number of reports among males aged 55 (±5) who have the condition, regardless of which drug is taken |
| Irritability in Anxiety Disorder | 2 (0.93%) |
| Irritability in Sleeplessness | 19 (0.75%) |
(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)
| Side effect | Number of reports among males aged 55 (±5) who take the drug |
| Irritability in Wellbutrin | 33 (1.18%) |
| Irritability in Advil Pm | 0 (0.00%) |
Most common interactions experienced by males aged 55 (±5) in the use of Wellbutrin, Advil Pm:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Hypotension | 3 |
| 2 | Deep Vein Thrombosis | 2 |
| 3 | Headache | 2 |
| 4 | Insomnia | 2 |
| 5 | Renal Failure Acute | 2 |
| 6 | Death | 2 |
| 7 | Neoplasm Malignant | 1 |
| 8 | Lung Neoplasm | 1 |
| 9 | Adrenal Neoplasm | 1 |
| 10 | Weight Decreased | 1 |
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Most common interactions experienced by males aged 55 (±5) in long term use of Wellbutrin, Advil Pm:
(click on each outcome to view in-depth analysis, incl. how people recovered)| None. |
For people in general (regardless of gender or age):
Comparison with this patient's adverse outcomes:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports among people in general who take the drugs |
| Irritability | 0 (0.00%) |
(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many HBP patients have nausea)
| Symptom | Number of reports among people in general who have the condition, regardless of which drug is taken |
| Irritability in Anxiety Disorder | 97 (2.85%) |
| Irritability in Sleeplessness | 391 (1.10%) |
(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many Aspirin users have nausea)
| Side effect | Number of reports among people in general who have the side effect while taking the drug |
| Irritability in Wellbutrin | 797 (1.80%) |
| Irritability in Advil Pm | 0 (0.00%) |
Most common interactions experienced by people in the use of Wellbutrin, Advil Pm:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Completed Suicide | 46 |
| 2 | Respiratory Arrest | 36 |
| 3 | Cardiac Arrest | 32 |
| 4 | Toxicity To Various Agents | 28 |
| 5 | Cardiogenic Shock | 21 |
| 6 | Death | 21 |
| 7 | Hypotension | 19 |
| 8 | Cardio-respiratory Arrest | 18 |
| 9 | Drug Toxicity | 18 |
| 10 | Pain | 17 |
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Most common interactions experienced by people in long term use of Wellbutrin, Advil Pm:
(click on each outcome to view in-depth analysis, incl. how people recovered)| None. |
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Drug effectiveness in real world:
- Wellbutrin for Anxiety Disorder reported by 11 people (updated 6 days ago)
- Advil Pm for Sleeplessness reported by 35 people (updated 2 months ago)
In-depth study of side effects (who have it, when it happens and how):
- Irritability in Wellbutrin reported by 797 people (updated 3 days ago)
- Irritability in Advil Pm
Could it be a symptom from a condition:
- Irritability in Anxiety Disorder reported by 97 people (updated 3 months ago)
- Irritability in Sleeplessness reported by 391 people (updated 3 months ago)
Side effects in real world:
Alternative drugs:
- Anxiety Disorder (81 drugs) (updated 7 hours ago)
- Sleeplessness (91 drugs) (updated 3 hours ago)
Drugs in real world that are associated with:
Comments from related studies:
From this study (1 year ago):
Been having alot of anxiety and high blood pressure. Worried that I'm taking so much medication!
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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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