Zanaflex, Excedrin, Clonazepam for a 75-year old man
Summary: 12 male patients aged 75 (±5) who take the same drugs are studied.
This is a personalized study for a 75 year old male patient who has Neck Pain, Frequent Headaches, Panic attacks. The study is created by eHealthMe based on reports from FDA and social media.
What are the drugs
Zanaflex has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. (latest outcomes from Zanaflex 7,305 users)
Excedrin has active ingredients of acetaminophen; aspirin; caffeine. It is often used in headache. (latest outcomes from Excedrin 7,810 users)
Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from Clonazepam 41,274 users)
What are the conditions
Neck pain can be treated by Ibuprofen, Flexeril, Gabapentin, Skelaxin, Cyclobenzaprine Hydrochloride, Methocarbamol. (latest reports from Neck Pain 23,791 patients)
Frequent headaches (pain in head) can be treated by Ibuprofen, Excedrin, Tylenol, Aspirin, Advil, Fioricet. (latest reports from Frequent Headaches 165,596 patients)
Panic attacks can be treated by Xanax, Klonopin, Clonazepam, Zoloft, Lorazepam, Alprazolam. (latest reports from Panic Attacks 23,381 patients)
On Dec, 2, 2014: 12 males aged 71 (±5) who take Zanaflex, Excedrin, Clonazepam are studied
Information of the patient in this study:
Conditions: Neck Pain, Frequent Headaches, Panic attacks
- Zanaflex - EQ 2MG BASE (tizanidine hydrochloride)
- Excedrin (acetaminophen; aspirin; caffeine): used for 10+ years
- Clonazepam (clonazepam): used for 6 - 12 months
eHealthMe real world results:
Drug effectiveness over time :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Zanaflex is effective||n/a||0.00%|
(0 of 1 people)
|Excedrin is effective||n/a||n/a||n/a||n/a||n/a||100.00%|
(1 of 1 people)
|Clonazepam is effective||n/a||n/a||n/a||n/a||n/a||n/a||n/a||n/a|
Most common drug interactions over time * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Fall||n/a||n/a||n/a||n/a||n/a||n/a||Delirium (wild excitement)|
|Abdominal Pain||Abdominal Pain|
|Delirium (wild excitement)||Fall|
|Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)||Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)|
|Joint Contracture (a permanent shortening of a muscle or joint)||Somnolence (a state of near-sleep, a strong desire for sleep)|
|Hand Deformity||Hypotonia (low muscle tone)|
|Muscular Weakness (muscle weakness)|
|Hypotension (abnormally low blood pressure)|
|Injection Site Pain|
* Some reports may have incomplete information.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
You can also:
- Check your drugs or symptoms
- Subscribe the study: get notified of updates
- Post a comment: or see what other people said about the study
- Join a related mobile support group
You are not alone! Join a related mobile support group:
- support group for people who have Frequent Headaches
- support group for people who have Neck Pain
- support group for people who have Panic Attacks
- support group for people who take Clonazepam
- support group for people who take Excedrin
- support group for people who take Zanaflex
Can you answer these questions (Ask a question):
- Adding low dose [25 mg] of quetiapine fuarate to bupropion hcl sr 12 hr [150 mg], cymbalta [60 mg] & gabapentin [300 mg] for sleep aid.
rear ended three years ago resulting in nerve damage in back head and back neck. Placed on 2 each 300mg 3 times a day w/o much success. Follow-up with PT and "trigger point" infections to relax nexk muscles which allowed for effective PT. Later receive more long term botax injections. Later prescribed Cymbalta [60 mg] to assist with pain management in neck and head.
Dr suspects pain management dug relapse [other than above] and am now in pain management drug withdrawal. Resulted in sever sleep problem and low dose [25mg] Quetiapine Fumarate as a sleep aid.
I am concerned with drug interaction between Bupropion Hcl Sr 24 hour, Gabapentin, Cymbalta and low dose Quetiapine Fumarate
- What are the drug interaction between andrgel and xanax
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- A life of depression and fatigue
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- Dyphenhydramine and headaches horrible going one almost 24 hours a day for 4 weeks and cant get them to stop, now looking for cause . think its the dyphenhydramine im taking to help me sleep .
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- 3 strong drugs together against neuropathic pain
Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.
The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.
The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.
It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.
There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.
Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.
The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).
Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.
I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
Comments from related studies:
From this study (7 months ago):
From this study (7 months ago):
Itching in extremeties with no rash apparent. Eyes watery and burning. Twitching is in left eyelid. Itching started 8 days ago. Lotion does not help much. Diphenhydramine does not help much.
Been on MS ContinSR 100mg, Tizanadine(Zanaflex) 4mg for 10+years and it does not much at all to help, also MS Contin 15mgIR in between. Pain is severe, fatigue is extreme, lack of sleep is hardest. Just started Temazepam for sleep,insurance co's. wants huge co pay for Ambien so had to go with something old for sleeep. Savella, just started on..no idea yet if it's going to help.
Due to fatigue, lack of sleep, extreme bone and muscle pain bones have turned in degenerative disc disease. Exercise is what is impossible to do due to pain,lack of sleep.
Linda on Jun, 9, 2014:
Female, age 52, Fibro and Ankylosing Spondylitis. I took Ambien for one or two years. Either a) didn't work at all,
b) worked too well and I was hung over the next day or
c) made me walk in my sleep. Once I cleanly the whole house in my sleep, which was a nice surprise the next morning. But once I took a huge butcher knife and hid it under the bed.
Related drug interaction studies:
Drug effectiveness in real world:
- Zanaflex for Neck Pain reported by 5 people (updated 2 days ago)
- Excedrin for Frequent Headaches reported by 174 people (updated 13 hours ago)
- Clonazepam for Panic Attacks reported by 134 people (updated 5 days ago)
Complete drug side effects:
- Frequent Headaches (92 drugs in 1,818 reports) (updated 38 minutes ago)
- Neck Pain (41 drugs in 281 reports) (updated 2 weeks ago)
- Panic Attacks (48 drugs in 1,295 reports) (updated 10 hours ago)
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
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