A study for a 47-year old woman who takes coumadin, Miralax, Topamax, lyrica
Summary: 21 female patients aged 47 (±5) who take the same drugs are studied.
This is a personalized study for a 47 year old female patient who has Deep Vein Thrombosis, Constipation, Migraine, Neuropathic Pain. The study is created by eHealthMe based on reports from FDA and social media.
What are the drugs
Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. (latest outcomes from 75,111 Coumadin users)
Miralax has active ingredients of polyethylene glycol 3350. It is often used in constipation. (latest outcomes from 9,278 Miralax users)
Topamax has active ingredients of topiramate. It is often used in migraine. (latest outcomes from 24,610 Topamax users)
Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from 66,603 Lyrica users)
What are the conditions
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis) can be treated by Warfarin Sodium, Coumadin, Lovenox, Xarelto, Aspirin, Arixtra. (latest reports from 43,395 Deep Vein Thrombosis patients)
Constipation can be treated by Miralax, Colace, Amitiza, Senna, Lactulose, Polyethylene Glycol 3350. (latest reports from 81,454 Constipation patients)
Migraine (headache) can be treated by Topamax, Imitrex, Topiramate, Maxalt, Amitriptyline Hydrochloride, Propranolol Hydrochloride. (latest reports from 51,717 Migraine patients)
Neuropathic pain (pain due to nerve inflammation and damage) can be treated by Gabapentin, Lyrica, Neurontin, Cymbalta, Amitriptyline Hydrochloride, Nortriptyline Hydrochloride. (latest reports from 1,270 Neuropathic Pain patients)
On Feb, 1, 2015: 21 females aged 41 (±5) who take coumadin, Miralax, Topamax, lyrica are studied
Information of the patient in this study:
Conditions: Deep Vein Thrombosis, Constipation, Migraine, Neuropathic Pain
- coumadin (warfarin sodium): used for 6 - 12 months
- Miralax (polyethylene glycol 3350): used for < 1 month
- Topamax (topiramate): used for 1 - 2 years
- lyrica (pregabalin): used for 1 - 6 months
eHealthMe real world results:
Drug effectiveness over time :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|coumadin is effective||n/a||n/a||n/a||n/a||n/a||n/a||n/a||n/a|
|Miralax is effective||n/a||n/a||n/a||0.00%|
(0 of 1 people)
|Topamax is effective||n/a||n/a||n/a||n/a||n/a||n/a||0.00%|
(0 of 1 people)
|lyrica is effective||n/a||n/a||0.00%|
(0 of 1 people)
Most common drug interactions over time * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Fatigue (feeling of tiredness)||n/a||Night Sweats (sweating in night)||Shortness Of Breath||n/a||n/a||Inflammatory Pain||Impaired Healing|
|Insomnia (sleeplessness)||Insomnia Related To Another Mental Condition (sleeplessness related to another mental condition)||Confusional State||Confusional State||Injury|
|Vision Blurred||Loss Of Control Of Legs||Headache (pain in head)||Chest Pain||Intervertebral Disc Protrusion (spinal disc protrusion)|
|Weight Increased||Muscle Contractions Involuntary (uncontrolled muscle contraction)||Exhaustion, Fatigue, Lethargy, Tiredness, Weariness (feeling of tiredness)||Exhaustion, Fatigue, Lethargy, Tiredness, Weariness (feeling of tiredness)||Mastication Disorder (disease of chewing food)|
|Loss Of Appetite (lack of feeling to eat)||Muscle Fatigue (a condition in which muscles cannot exert their normal force)||Muscle Fatigue (a condition in which muscles cannot exert their normal force)||Malnutrition (condition that results from eating a diet in which certain nutrients are lacking)|
|Sacral Pain (pain at sacrum bone region)||Loss Of Control Of Legs||Fall||Granulocytopenia (lack of granulocyte)|
|Swelling||Night Sweats (sweating in night)||Night Sweats (sweating in night)||Gastritis (inflammation of stomach)|
|Fall||Palpitations Aggravated (feelings or sensations that your heart is pounding or racing- aggravated)||Sacral Pain (pain at sacrum bone region)||Dental Caries|
|Muscle Fatigue (a condition in which muscles cannot exert their normal force)||Insomnia Related To Another Mental Condition (sleeplessness related to another mental condition)||Palpitations Aggravated (feelings or sensations that your heart is pounding or racing- aggravated)||Depression|
|Inflammatory Pain||Fall||Shortness Of Breath||Disability|
* Some reports may have incomplete information.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
You can also:
- Check your drugs or symptoms
- Subscribe the study: get notified of updates
- Post a comment: or see what other people said about the study
- Join a related mobile support group
You are not alone! Join a related mobile support group:
- support group for people who have Constipation
- support group for people who have Deep Vein Thrombosis
- support group for people who have Migraine
- support group for people who have Neuropathic Pain
- support group for people who take Miralax
- support group for people who take Topamax
- support group for people who take Coumadin
- support group for people who take Lyrica
Recent conversations of related support groups:
- Support group for people who take Lyrica
I have gained about 35 pounds, and I have the cognitive effects listed in the prescribing information--problems with thinking and concentration." I've been off Lyrica once, and the side effects went away, but I couldn't get out of bed in the morning
Can you answer these questions (Ask a question):
- Does topamax effect sexual desire and cause weight gain (2 answers)
I have taken topamax for 10 years and have been gaining weight steadily every year. My doctor says the medication is not the reason because Topamax causes people to loose weight. I have also voiced my concerns to him that since I started taking this medication I have no desire for sex. He says this medication would not affect this. Please help so I can get him to change my medication.
- Can sulfalazine cause bed wetting
I had been taking the Sulfalazine for around 6 months with no real side effects, Then twice in one week I lost control of my bladder while sleeping. This has never happened to me before. My GP took me off the sulfalazine and I was fine, He had thought they where causing some sort of convulsion while Sleeping. About 6 weeks later my GP rand and told me to go back on them as he no longer thought that they where causing the problem, 5 days in and it has just happened again, My bed and myself soaked, It's completley frustrating, Can any one please help with any suggestions?
- Have you noticed extreme edema after taking both of these drugs?
I have been taking Topamax for years for treatment of migraine headaches. Two months ago I was placed on Lithium and Latuda for Mood Disorder NOS. I had a host of bad reactions to both drugs and have since been removed. A week ago I started taking Tegretol. Since coming down off the Lithium and starting the Tegretol with the Topamax I have started retaining another water to fill up Death Valley. Just wondering if this was a aide effect of the medication or something else.
- How are people being treated with may-thurner syndrome?
I was diagnosed with May-Thurner Syndrome after two DVT's five years apart. Have been treated with Coumadin for the last 10 years but now a Doctor has changed me to Plavix and aspirin therapy.
- How often does thromboyctopenia occur?
73 year old patient with thrombocytopenia of unknown origin. He has failed Rituxin treatments and initial therapy with steroids has actually caused his platelets to lower. Requesting to see if his current medications may be the culprit.
You may be interested at these reviews (Write a review):
- Constipation from the drug that the doctor recommended i take
I am active not overweight and not on any other drugs. Went to the hospital with severe pain ever since nov. 2014 up until 02/2015 i have experienced constipation. Never ever had problems like this since i started this drug. I dont smoke or drink. work out each day and eat before 8 at night. Not to sure what is up.
- Lyrica is giving me nightmares
I have fibromyalgia and a history of being allergic to or very sensitive to medications
But Lyrica is really causing me some nightmares,sleepless nights, weight gain, headaches. I love that in the beginning I was able to get relief from fibromyalgia . It only made me really dizzy and disoriented on it. Now with theses symptoms I will definitely have to give it up. I can't seem to get any relief from this pain. I am so allergic to meds this is frustrating and miserable that meds make it worse.
- Lyrica and doxylamine - not a good cocktail!
I've been taking Lyrica 125mg total per day in 2x doses for 6 weeks, a few manageable side effects, (gaining weight and feeling dopey) I don't like it, but I recognise its ability to reduce @ 50% of the nerve pain and ability to help me function at work while I wait to see the surgeon.
I took 50mg Doxylamine at night as a suggestion from a pharmacist to help sleep. Not a great idea! In the morning I was dulled, dopey. My speech was slurred, it made thinking very difficult and I couldn't drive safely. Felt spacey and stoned. For 48 hours!!! Even taking just 25mgs had long lasting side effects.
I don't recommend this cocktail!
- Toperimate has ruined my life!
On Dec 2, 2015 I started taking Toperimate for severe back pain. Within 48 -36 hours I became very sick - throwing up, nausea, blood in my feces, putrid taste in mouth, blurry eyes, difficulty sleeping, confusion and severe fatigue. I felt like I was poisoning myself! After 7 days I felt no improvement to my back pain and was in pretty bad shape. So I made the decision to go off of it after day 7's dose. On day 9, I woke up with severe VERTIGO. I thought I was dying, it was so bad! Was it a brain tumor (I wondered at the time, horrified!)? I didn't know. I believe (actually I KNOW) it was a side effect of the Toperimate, which can cause vertigo. I also immediately began to feel drunk all the time, even when I wasn't "spinning". I had vertigo and the drunk feeling for 1week and then I went to Urgent Care. The doctor was useless and only gave me Valium. No answers, no improvement. I waited 3 more weeks, desperate, and again went to second UC doctor. This one was competent. He diagnosed me with BVVP ( Benign Paroxysmal Positional Vertigo - which us caused by dislodged calcium crystals in my inner ear.) and set me up to have the Epley Manuever through Vestibular Rehab Physical Therapy. My vertigo was (temporarily) corrected after the first PT visit. Although I was thrilled, I was STILL feeling drunk. I've had both an MRI and MRA to rule out brain rumors, etc. everything, thank God, came out clean. Yes! But I still felt drunk 24/7. 3 weeks after The Physical Therapist corrected my vertigo. It fully came back. I was devastated! But I was able to correct it myself by doing the Epley Maneuver by myself at home. I watched a Youtube Video for instructions. I need to mention that I believe I caused the vertigo to return the second time because the night before it returned, my husband used a vibrating massager on the back of my head/upper neck area because I had pain there. I learned from my PT that the vibrations could have again dislodged the calcium crystals in my inner ear. Strange, right? She said often the PTs use vibration to force the crystals back where they're supposed to be. Apparent, the opposite is true too. Well, today is February 2, 2015. I haven't had a recurrence of my vertigo but I STILL FEEL DRUNK 24/7!!!! Thanks Toperimate and it's makers, and the doctor that gave it to me. It was supposedly a "conservative approach" to my back pain, but the question is......will I ever feel normal again? If I do heal from this, I will try to remember to update this webpage again. Good luck to anyone who experiences this problem.
- Nightmares from miralax
Used for an endoscopy prep, great for what it does but gave me horrid and vivid nightmares
Comments from related studies:
From this study (2 weeks ago):
From this study (2 months ago):
From this study (12 months ago):
I am currently experiencing constant muscle contractions in my abdomen and jerking movements in my neck and midsection. My neck will pull back by itself... Or while I'm standing I'll involuntarily bend over. I'm also having balance issues. I feel very unstable walking and am experiencing some tremors.
All this occurred when I started taking the Lipitor. I'm waiting on a phone call from my doctor.
I have an non-typical pulmonary stenosis, MPA aneurysm directly above that valve. The left ventricle was also enlarged due to the stress of my third & final pregnancy put on my heart.
On March 1st (this year) I went to the ER as none of my asthma treatment weren't working. After several tests a pulmonary embolism was found in my bronchial trunk. It was successfully dissolved with heparin in 48 hours. The PE put more stress on the left ventricle. As a result I was sent home to be on bed rest as I only had trouble breathing while mobile, under stress or attempting to carry on a conversation. At rest, my heart rate & oxygen meter would go back to normal.
That is no longer the case. When I went in to my Asthma & allergy doctor's office to do my PFT, it was worse than it has ever been, including before I quit smoking 5yrs. ago. This started at the same time I began taking Coumadin & became worse as I reached therapeutic INR levels.
Related drug interaction studies:
- Topamax and Miralax drug interactions (259 reports)
- Coumadin and Topamax drug interactions (602 reports)
- Lyrica and Miralax drug interactions (650 reports)
- Lyrica and Topamax drug interactions (1,149 reports)
- Lyrica and Coumadin drug interactions (2,045 reports)
- Miralax and Coumadin drug interactions (1,089 reports)
Drug effectiveness in real world:
- Coumadin for Deep Vein Thrombosis reported by 227 people (updated 1 hour ago)
- Miralax for Constipation reported by 237 people (updated 14 hours ago)
- Topamax for Migraine reported by 723 people (updated 2 minutes ago)
- Lyrica for Neuropathic Pain reported by 74 people (updated 1 week ago)
Complete drug side effects:
- Constipation (26 drugs in 825 reports) (updated 14 hours ago)
- Deep Vein Thrombosis (13 drugs in 645 reports) (updated 1 hour ago)
- Migraine (130 drugs in 3,879 reports) (updated 2 minutes ago)
- Neuropathic Pain (15 drugs in 314 reports) (updated 4 days ago)
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.