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From FDA reports: drug interactions between Keppra, Lamictal, Trileptal for a Female patient aged 25

This is a personalized study for a 25 year old female patient. The study is created by eHealthMe based on reports of 143 people who take the same drugs and have drug interactionsfrom FDA.

On Dec, 15, 2014: 143 people who reported to have interactions when taking Keppra, Lamictal, Trileptal are studied

Trend of Keppra, Lamictal, Trileptal's drug interactions, side effects, and effectiveness reports (1332119)

Information of the patient in this study:

Age: 25

Gender: female

Conditions: Partial Seizures

Drugs taking:
- Keppra
- Lamictal
- Trileptal

Drug interactions have: Asthenia, Autoimmune Thrombocytopenia, Ecchymosis, Epistaxis, Folate Deficiency, Hypergammaglobulinaemia, Idiopathic Thrombocytopenic Purpura, Menorrhagia, Normochromic Normocytic Anaemia

eHealthMe real world results:

Comparison with this patient's adverse outcomes among females aged 25 (±5):

InteractionNumber of reports
Asthenia (weakness)4 (16.67%)
Autoimmune Thrombocytopenia (isolated low platelet count (thrombocytopenia) with normal bone marrow and the absence of other causes of thrombocytopenia)2 (8.33%)
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)4 (16.67%)
Epistaxis (bleed from the nose)4 (16.67%)
Folate Deficiency (lack of folic acid)4 (16.67%)
Hypergammaglobulinaemia (elevated levels of gamma globulin)4 (16.67%)
Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting)6 (25.00%)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)6 (25.00%)
Normochromic Normocytic Anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits)2 (8.33%)

Most common interactions experienced by females aged 25 (±5) in the use of Keppra, Lamictal, Trileptal:

InteractionNumber of reports
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)16
Grand Mal Convulsion (a type of generalized seizure that affects the entire brain)10
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)6
Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting)6
Fatigue (feeling of tiredness)6
Drug Ineffective6
Fear4
Malaise (a feeling of general discomfort or uneasiness)4
Muscle Twitching4
Drug Effect Decreased4

Most common interactions experienced by females aged 25 (±5) in long term use of Keppra, Lamictal, Trileptal:

None.

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
Asthenia (weakness)12 (8.39%)
Autoimmune Thrombocytopenia (isolated low platelet count (thrombocytopenia) with normal bone marrow and the absence of other causes of thrombocytopenia)2 (1.40%)
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)4 (2.80%)
Epistaxis (bleed from the nose)4 (2.80%)
Folate Deficiency (lack of folic acid)4 (2.80%)
Hypergammaglobulinaemia (elevated levels of gamma globulin)4 (2.80%)
Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting)6 (4.20%)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)6 (4.20%)
Normochromic Normocytic Anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits)4 (2.80%)

Most common interactions experienced by people in the use of Keppra, Lamictal, Trileptal:

InteractionNumber of reports
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)62
Drug Ineffective44
Grand Mal Convulsion (a type of generalized seizure that affects the entire brain)38
Rash (redness)27
Dizziness27
Fatigue (feeling of tiredness)25
Suicidal Ideation24
Speech Disorder22
Nausea (feeling of having an urge to vomit)22
Headache (pain in head)22

Most common interactions experienced by people in long term use of Keppra, Lamictal, Trileptal:

InteractionNumber of reports
Dizziness3
Weight Decreased2
Neurosis (a class of functional mental disorders involving distress but neither delusions nor hallucinations)2
Nausea (feeling of having an urge to vomit)2
Malaise (a feeling of general discomfort or uneasiness)2
Ill-defined Disorder2
Ataxia (loss of full control of bodily movements)2
Ageusia (loss of taste functions of the tongue)2
Somnolence (a state of near-sleep, a strong desire for sleep)2
Balance Disorder2

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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