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From FDA reports: drug interactions between Omeprazole, Metronidazole, Clarithromycin 250, Isosorbit Dinitrate for a Female patient aged 86

This is a personalized study for a 86 year old female patient. The study is created by eHealthMe based on reports of 302 people who take the same drugs and have drug interactionsfrom FDA.

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On May, 13, 2014: 302 people who reported to have interactions when taking Omeprazole, Metronidazole, Clarithromycin 250, Isosorbit Dinitrate are studied

Trend of Omeprazole, Metronidazole, Clarithromycin 250, Isosorbit Dinitrate's drug interactions, side effects, and effectiveness reports (2305684)

Information of the patient in this study:

Age: 86

Gender: female

Drugs taking:
- Omeprazole
- Metronidazole
- Clarithromycin 250
- Isosorbit Dinitrate

Drug interactions have: Colitis Pseudomembranous, Dehydration, Vertigo Nec

eHealthMe real world results:

Comparison with this patient's adverse outcomes among females aged 86 (±5):

InteractionNumber of reports
Colitis Pseudomembranous (antibiotic-associated diarrhoea)6 (37.50%)
Dehydration (dryness resulting from the removal of water)8 (50.00%)
Vertigo Nec3 (18.75%)

Most common interactions experienced by females aged 86 (±5) in the use of Omeprazole, Metronidazole, Clarithromycin 250, Isosorbit Dinitrate:

InteractionNumber of reports
Dizziness13
Decreased Appetite (decreased appetite occurs when you have a reduced desire to eat)12
Constipation10
Dehydration (dryness resulting from the removal of water)8
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)8
Sputum Increased8
Blood Beta-d-glucan Increased8
Sputum Purulent8
Abdominal Pain Nos6
Colitis Pseudomembranous (antibiotic-associated diarrhoea)6

Most common interactions experienced by females aged 86 (±5) in long term use of Omeprazole, Metronidazole, Clarithromycin 250, Isosorbit Dinitrate:

None.

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
Colitis Pseudomembranous (antibiotic-associated diarrhoea)8 (2.65%)
Dehydration (dryness resulting from the removal of water)50 (16.56%)
Vertigo Nec5 (1.66%)

Most common interactions experienced by people in the use of Omeprazole, Metronidazole, Clarithromycin 250, Isosorbit Dinitrate:

InteractionNumber of reports
Anxiety283
Hypertension (high blood pressure)222
Palpitations (feelings or sensations that your heart is pounding or racing)207
Diarrhoea197
Pain164
Injury155
Nausea (feeling of having an urge to vomit)142
Cough136
Anhedonia (inability to experience pleasure from activities usually found enjoyable)128
Fall122

Most common interactions experienced by people in long term use of Omeprazole, Metronidazole, Clarithromycin 250, Isosorbit Dinitrate:

InteractionNumber of reports
Dyspnoea (difficult or laboured respiration)4
Coronary Artery Disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)4
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)4
Palpitations (feelings or sensations that your heart is pounding or racing)4
Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)4
Cerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)4
Pleuritic Pain4
Abdominal Pain Upper4
Cholecystitis (infection of gallbladder)4
Cough4

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Comments from related studies:

  • From this study (4 weeks ago):

  • I have had crohns disease since 1990 and was diagnosed with ulcerative colitis 3 years ago. I have osteoarthritis, fibromyalga, hypothyroid since 1980. I just recently started experiencing lightheadedness, dizziness, headaches,feeling faint and feeling as if i was going to be sick to my stomach all at the same time about 2 weeks ago. I am under a little stress, my cousin just passed away. I am also on 30 mg's of prednisone and have been since the end of April 2014

    Reply

  • From this study (1 year ago):

  • In Nov. I had one seizure (lasted 3 min.) like episode, unconscious for 15 minutes, taken by ambulance to ER. ER said Syncope and Dehydration. One month later I had brain EEG and Neurologist said result was "Non-specific Abnormal brain activity". Advised to treat fevers asap (which was not the issue), and stay hydrated. Feeling dehydrated and constant urination has been a problem the last few years, prior to Lyme diagnosis and any treatments. I drink more than enough water and now pedialite twice a day.
    Although not on drug list, I do take Transfer Factor PlasMyc for Mycoplasma. Just started Milk Thistle also for detox.
    Any thoughts or suggestions would be great!

    Reply

    Lucia Cargill, phD, FNP-C on Apr, 5, 2013:

    For kindred spirits and much technical info, plus treatment standards, check out ILADS online. Also, see the Institute for Functional Medicine for integrative primary care doctors near by.

    Reply

  • From this study (1 year ago):

  • Since beginning Topamax about 6 weeks ago, have become weaker, and weaker until I can barely function. Have chronic sinus issues, am being treated for infection, doctor suspected mycoplasm for the weakness and put me on Doxycycline. I suspect it is the Topamax.

    Reply

    MG Quay on Mar, 14, 2013:

    I am a 59 yr old female. I've used Topamax for the past 7-8 yrs. It is a Seizure Medication, with a side effect of helping migraine headaches, (which is how I started taking it). Works wonders for the extreme Life-long migraines I suffered since age of 10, but the only drawback is that it is well known to make you VERY, VERY forgetful - almost as if early senility is setting in. It really impairs clear thinking and reactions. At high doses, makes you groggy.
    I've known even teens on the meds that have suffered memory loss and lack of concentration while taking this for headaches.

    Plus, magnesium should be supplemented, as it has been rumored to deplete this from your system. But other than making a person sleepy at higher doses, I don't believe it should be used with the phentermine diet drug, since this med causes the same types of effects, and should not be used with ANY OTHER TYPE OF DIET DRUG.
    Use Topamax only if you suffer seizures, but most all the other meds show asthma or breathing problems. I would treat one illness and get that under control before trying to overload on meds that can counteract. The Topamax, while known to MAY, and I stress MAY cause weight loss, if that is the reason it is prescribed, is only a short term thing. So if you suffer migraines, or seizures, stay on Topamax - and dose does not have to be high, and drop the phentermine. Or Vice Versa.

    Reply

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