A study of drug interactions between Omeprazole, Metronidazole, Clarithromycin 250, Isosorbit Dinitrate for a Female patient aged 86
This is a personalized study of Omeprazole, Metronidazole, Clarithromycin 250, Isosorbit Dinitrate drug interactions for a 86 year old female patient. The study is created by eHealthMe based on 299 reports from FDA.
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What are the drugs
Omeprazole has active ingredients of omeprazole. It is used in gastroesophageal reflux disease, gastric ulcer, indigestion, reflux gastritis, stomach discomfort, gastroesophageal reflux in infants.
Metronidazole has active ingredients of metronidazole. It is used in vaginitis bacterial, infection, bacterial infection, diverticulitis, tooth abscess, vaginal infection.
Clarithromycin 250 has active ingredients of clarithromycin.
Isosorbit dinitrate has active ingredients of isosorbide dinitrate.
On Apr, 24, 2013: 299 people who reported to have interactions when taking Omeprazole, Metronidazole, Clarithromycin 250, Isosorbit Dinitrate are studied

Information of the patient in this study:
Age: 86
Gender: female
Drugs taking:
- Omeprazole
- Metronidazole
- Clarithromycin 250
- Isosorbit Dinitrate
Drug interactions have: Colitis Pseudomembranous, Dehydration, Vertigo Nec
eHealthMe real world results:
For females aged 86 (±5):
Comparison with this patient's adverse outcomes:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports |
| Colitis Pseudomembranous | 3 (18.75%) |
| Dehydration | 4 (25.00%) |
| Vertigo Nec | 2 (12.50%) |
Most common interactions experienced by females aged 86 (±5) in the use of Omeprazole, Metronidazole, Clarithromycin 250, Isosorbit Dinitrate:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Dizziness | 5 |
| 2 | Bradycardia | 4 |
| 3 | Constipation | 4 |
| 4 | Weakness | 4 |
| 5 | Hyperkalaemia | 4 |
| 6 | Dehydration | 4 |
| 7 | Colitis Pseudomembranous | 3 |
| 8 | Abdominal Pain Nos | 3 |
| 9 | Injury | 2 |
| 10 | Prothrombin Time Prolonged | 2 |
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Most common interactions experienced by females aged 86 (±5) in long term use of Omeprazole, Metronidazole, Clarithromycin 250, Isosorbit Dinitrate:
(click on each outcome to view in-depth analysis, incl. how people recovered)| None. |
For people in general (regardless of gender or age):
Comparison with this patient's adverse outcomes:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports |
| Colitis Pseudomembranous | 4 (1.34%) |
| Dehydration | 17 (5.69%) |
| Vertigo Nec | 3 (1.00%) |
Most common interactions experienced by people in the use of Omeprazole, Metronidazole, Clarithromycin 250, Isosorbit Dinitrate:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Anxiety | 134 |
| 2 | Hypertension | 102 |
| 3 | Palpitations | 94 |
| 4 | Pain | 62 |
| 5 | Injury | 54 |
| 6 | Nausea | 52 |
| 7 | Anhedonia | 44 |
| 8 | Cough | 44 |
| 9 | Fall | 42 |
| 10 | Emotional Distress | 41 |
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Most common interactions experienced by people in long term use of Omeprazole, Metronidazole, Clarithromycin 250, Isosorbit Dinitrate:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Coronary Artery Disease | 4 |
| 2 | Cholelithiasis | 4 |
| 3 | Myocardial Infarction | 4 |
| 4 | Palpitations | 4 |
| 5 | Cerebrovascular Accident | 4 |
| 6 | Cholecystitis | 3 |
| 7 | Bronchitis | 3 |
| 8 | Cough | 3 |
| 9 | Pleuritic Pain | 3 |
| 10 | Abdominal Pain Upper | 3 |
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In-depth study of side effects (who have it, when it happens and how):
- Colitis Pseudomembranous in Omeprazole (43 reports)
- Colitis Pseudomembranous in Metronidazole (65 reports)
- Dehydration in Omeprazole (2,137 reports)
- Dehydration in Metronidazole (331 reports)
- Vertigo Nec in Omeprazole
- Vertigo Nec in Metronidazole
Comments from related studies:
From this study (2 months ago):
From this study (2 months ago):
From this study (1 year ago):
In Nov. I had one seizure (lasted 3 min.) like episode, unconscious for 15 minutes, taken by ambulance to ER. ER said Syncope and Dehydration. One month later I had brain EEG and Neurologist said result was "Non-specific Abnormal brain activity". Advised to treat fevers asap (which was not the issue), and stay hydrated. Feeling dehydrated and constant urination has been a problem the last few years, prior to Lyme diagnosis and any treatments. I drink more than enough water and now pedialite twice a day.
Although not on drug list, I do take Transfer Factor PlasMyc for Mycoplasma. Just started Milk Thistle also for detox.
Any thoughts or suggestions would be great!
Lucia Cargill, phD, FNP-C on Apr, 5, 2013:
For kindred spirits and much technical info, plus treatment standards, check out ILADS online. Also, see the Institute for Functional Medicine for integrative primary care doctors near by.
Since beginning Topamax about 6 weeks ago, have become weaker, and weaker until I can barely function. Have chronic sinus issues, am being treated for infection, doctor suspected mycoplasm for the weakness and put me on Doxycycline. I suspect it is the Topamax.
MG Quay on Mar, 14, 2013:
I am a 59 yr old female. I've used Topamax for the past 7-8 yrs. It is a Seizure Medication, with a side effect of helping migraine headaches, (which is how I started taking it). Works wonders for the extreme Life-long migraines I suffered since age of 10, but the only drawback is that it is well known to make you VERY, VERY forgetful - almost as if early senility is setting in. It really impairs clear thinking and reactions. At high doses, makes you groggy.
I've known even teens on the meds that have suffered memory loss and lack of concentration while taking this for headaches.
Plus, magnesium should be supplemented, as it has been rumored to deplete this from your system. But other than making a person sleepy at higher doses, I don't believe it should be used with the phentermine diet drug, since this med causes the same types of effects, and should not be used with ANY OTHER TYPE OF DIET DRUG.
Use Topamax only if you suffer seizures, but most all the other meds show asthma or breathing problems. I would treat one illness and get that under control before trying to overload on meds that can counteract. The Topamax, while known to MAY, and I stress MAY cause weight loss, if that is the reason it is prescribed, is only a short term thing. So if you suffer migraines, or seizures, stay on Topamax - and dose does not have to be high, and drop the phentermine. Or Vice Versa.
Feeling sick and miserable all the time with all the above medications. House-bound and unable to socialise. Feeling dizzy and cannot ride in a car without vomiting. Am 70 y.o. Also taking Cod Liver Oil and Calcium tablets.
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- A study of drug interactions between Biotene, Hydroxyquinoline, Metformin, Acid Folic, Omeprazole, Ramipril, Crestor, Venlafaxine Hcl Extended-release, Celebrex, Cyclobenzaprine, Muro 128, Atasol Compound, Remicade for a patient with Rheumatoid Arthritis. The patient has Toe Operation
- A study of drug interactions between Losartan Potassium, Bupropion Hydrochloride, Terazosin Hydrochloride, Cilostazol, Furosemide, Ezetimibe, Simvastatin for a patient with High Blood Pressure, Smoking Cessation Therapy, Urinary Hesitation, Pain In Extremity, Edema, Cholesterol. The patient has Vomiting Projectile, Dizziness, Confusion, Fatigue Aggravated, Muscle Weakness
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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