Review: could Acetaminophen cause Anaphylaxis?


Anaphylaxis is found among people who take Acetaminophen, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Aspirin, and have Pain . We study 73,148 people who have side effects while taking Acetaminophen from FDA and social media. Among them, 482 have Anaphylaxis. Find out below who they are, when they have Anaphylaxis and more.

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are simple to use, anonymous and free. Start now >>>


Acetaminophen has active ingredients of acetaminophen. It is often used in pain. (latest outcomes from Acetaminophen 76,274 users)


Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death) has been reported by people with asthma, multiple sclerosis, high blood pressure, rheumatoid arthritis, preventive health care (latest reports from 41,100 Anaphylaxis patients).

On Nov, 23, 2016

73,148 people reported to have side effects when taking Acetaminophen.
Among them, 482 people (0.66%) have Anaphylaxis

Number of reports submitted per year:

Could Acetaminophen cause Anaphylaxis?

Time on Acetaminophen when people have Anaphylaxis *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Anaphylaxis when taking Acetaminophen *:

  • female: 58.95 %
  • male: 41.05 %

Age of people who have Anaphylaxis when taking Acetaminophen *:

  • 0-1: 0.23 %
  • 2-9: 5.58 %
  • 10-19: 8.14 %
  • 20-29: 9.53 %
  • 30-39: 11.86 %
  • 40-49: 13.72 %
  • 50-59: 20.0 %
  • 60+: 30.93 %

Top co-used drugs for these people *:

  • Aspirin (50 people, 10.37%)
  • Prednisolone (30 people, 6.22%)
  • Ibuprofen (30 people, 6.22%)
  • Furosemide (26 people, 5.39%)
  • Simvastatin (25 people, 5.19%)

Forecasts by (We will alert you to new symptoms or undetected conditions when you take Acetaminophen, learn more)

Potential co-existing conditions

  • High Blood Pressure (33 people, 6.85%)

Potential co-existing symptoms

  • Hypotension (76 people, 15.77%)
  • Breathing Difficulty (55 people, 11.41%)
  • Urticaria (42 people, 8.71%)
  • Rashes (37 people, 7.68%)
  • Chest Pain (32 people, 6.64%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Anaphylaxis when taking Acetaminophen?

Browse all side effects of Acetaminophen

a b c d e f g h i j k l m n o p q r s t u v w x y z

Drugs that are associated with Anaphylaxis


Could your condition cause Anaphylaxis


Related studies

Can you answer these questions?

More questions for: Acetaminophen, Anaphylaxis

You may be interested in these reviews

More reviews for: Acetaminophen, Anaphylaxis

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.