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Review: could Acetaminophen cause Joint swelling?

Summary: Joint swelling is found among people who take Acetaminophen, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Aspirin, and have Rheumatoid arthritis.

We study 69,447 people who have side effects while taking Acetaminophen from FDA and social media. Among them, 378 have Joint swelling. Find out below who they are, when they have Joint swelling and more.

You are not alone: join a mobile support group for people who take Acetaminophen and have Joint swelling >>>

 

 

 

 

Acetaminophen

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. (latest outcomes from 70,714 Acetaminophen users)

Joint swelling

Joint swelling has been reported by people with rheumatoid arthritis, high blood pressure, osteoporosis, pain, high blood cholesterol. (latest reports from 23,903 Joint swelling patients)

On Dec, 30, 2014: 69,441 people reported to have side effects when taking Acetaminophen. Among them, 378 people (0.54%) have Joint Swelling.

Trend of Joint swelling in Acetaminophen reports

Time on Acetaminophen when people have Joint swelling * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Joint swelling41.18%5.88%0.00%29.41%23.53%0.00%0.00%

Gender of people who have Joint swelling when taking Acetaminophen * :

FemaleMale
Joint swelling62.15%37.85%

Age of people who have Joint swelling when taking Acetaminophen * :

0-12-910-1920-2930-3940-4950-5960+
Joint swelling0.00%0.90%3.29%5.99%7.19%19.46%16.47%46.71%

Severity of Joint swelling when taking Acetaminophen ** :

leastmoderateseveremost severe
Joint swelling0.00%0.00%100.00%0.00%

How people recovered from Joint swelling ** :

while on the drugafter off the drugnot yet
Joint swelling0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (52 people, 13.76%)
  2. Pain (42 people, 11.11%)
  3. Multiple myeloma (20 people, 5.29%)
  4. Hypertension (19 people, 5.03%)
  5. Crohn's disease (17 people, 4.50%)

Top co-used drugs for these people * :

  1. Aspirin (104 people, 27.51%)
  2. Zometa (65 people, 17.20%)
  3. Omeprazole (59 people, 15.61%)
  4. Folic acid (57 people, 15.08%)
  5. Prednisone (52 people, 13.76%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

Comments for this study:

Randall Long (2 years ago):

Have a failed lower back fusion and been on low dose hydrocodone for 7 years. Last 3 years I have to have cortizone injections in my knees, and now the xrays shows bone to bone in my shoulder, Doc says its beyond cortizone and gives a numbing injections. Need a shoulder replacement. Is it from long term use of the pain meds or caffeine ?
In fairly good shape, not overweight. Thanks R.Long
Reply the comment

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Joint Swelling while taking Acetaminophen?

You are not alone! Join a mobile support group:
- support group for people who take Acetaminophen and have Joint Swelling
- support group for people who take Acetaminophen
- support group for people who have Joint Swelling

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Comments from related studies:

  • From this study (6 months ago):

  • I've been diagnosed with sero-negative rheumatoid arthritis. I have only tested minimally positive on the anti-CCP test and had a slightly high SED rate. My most recent tests showed some slight elevation in some RA marker tests, but nothing really significant. My rheumatologist is now doubting whether I have RA or some other pain syndrome going on.

    Reply

    IHateRA on Jul, 22, 2014:

    My first RA Dr. put me on Plaquenil, it seemed to work for six months, then stopped - I thought the dose would be adjusted but it wasn't, so I went to another RA Doc - C-RP wasn't too high, sero neg. Was put on methotrexate - I ended up with a mouth sore the NEXT day, then bumps started appearing on my face, like zits, but NOT zits. I didn't touch them, but they ulcerated, left me full of scars on face, legs, etc - I have been OFF methotrexate for 5 years AND still have the same problem along with a daily fever (100+) and severe sweating - I knew the bumps were a sign of being allergic to Methotrexate, I quit it right away, called Dr. to get in - they told me 3 months (I was an established patient). In terms of fever and sweating, the ONLY thing I have in common with some of these posts and drug lists is METHOTREXATE - I wouldn't allow a pet to take it. I seem to have more in common with a friend who as MS - but my reg. doc doesn't listen to that. I can't take bio. drugs (live in "fungal" region), so I take pain medicine - as little as possible, I guess the Methotrexate is STILL messing with my body. I have a very good acupuncturist - when I told him that my Doc. wasn't "sure" about RA, he poked me (lightly) with his finger in two places and ask which hurt more. He confirmed the RA as it travels on certain meridians in Chinese medicine. Had I picked a different spot for hurting more, then we would have to figure out what I really had. My joints are deteriorating but now I'm afraid of the drugs for RA, so I just put up with and manage the pain (which is extreme) with pain meds, cold therapy (I love my cryo-cuff), and acupuncture. I wish that the side effects of RA drugs weren't as bad as they are! Leaving Cymbalta, Lyrica, Plaquenil and Methotrexate (all at different times) OUT of my body made me realize that they did affect me - I was "foggy" and sluggish mentally but didn't really notice it until I quit them.

    Reply

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