Review: could Actos cause Colorectal Cancer?


Colorectal cancer is found among people who take Actos, especially for people who are male, 60+ old , have been taking the drug for 2 - 5 years, also take medication Glyburide, and have Diabetes mellitus . We study 31,701 people who have side effects while taking Actos from FDA and social media. Among them, 45 have Colorectal cancer. Find out below who they are, when they have Colorectal cancer and more.

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Actos has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. (latest outcomes from Actos 32,685 users)

Colorectal Cancer

Colorectal cancer (colon cancer or bowel cancer) has been reported by people with breathing difficulty, death, rashes, thrombocytopenia, agranulocytosis (latest reports from 23,890 Colorectal cancer patients).

On Aug, 27, 2016

31,701 people reported to have side effects when taking Actos.
Among them, 45 people (0.14%) have Colorectal Cancer

Number of reports submitted per year:

Could Actos cause Colorectal cancer?

Time on Actos when people have Colorectal Cancer *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 22.22 %
  • 1 - 2 years: 11.11 %
  • 2 - 5 years: 44.44 %
  • 5 - 10 years: 22.22 %
  • 10+ years: 0.0 %

Gender of people who have Colorectal Cancer when taking Actos *:

  • female: 31.82 %
  • male: 68.18 %

Age of people who have Colorectal Cancer when taking Actos *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 7.5 %
  • 50-59: 27.5 %
  • 60+: 65.0 %

Severity if Colorectal Cancer when taking Actos **:

  • least: 50 %
  • moderate: 0.0 %
  • severe: 0.0 %
  • most severe: 50 %

How people recovered from Colorectal Cancer **:

  • while on drug: 50 %
  • after off the drug: 0.0 %
  • not yet: 50 %

Top conditions involved for these people *:

  • Diabetes Mellitus (9 people)
  • Type 2 Diabetes Mellitus (8 people)
  • Prophylaxis (7 people)
  • Colorectal Cancer (7 people)
  • Diabetes Mellitus Non-Insulin-Dependent (5 people)

Top co-used drugs for these people *:

  • Glyburide (11 people)
  • Panitumumab (6 people)
  • Lipitor (6 people)
  • Aspirin (6 people)
  • Fluorouracil (5 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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