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Review: could Actos cause Colorectal cancer (Colon cancer)?





Summary: Colorectal cancer is found among people who take Actos, especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years, also take medication Glyburide, and have Prophylaxis.

We study 31,007 people who have side effects while taking Actos from FDA and social media. Among them, 41 have Colorectal cancer. Find out below who they are, when they have Colorectal cancer and more.

You are not alone: join a mobile support group for people who take Actos and have Colorectal cancer >>>

Actos

Actos has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. (latest outcomes from Actos 31,346 users)

Colorectal cancer

Colorectal cancer (colon cancer or bowel cancer) has been reported by people with rheumatoid arthritis, multiple sclerosis, colon cancer, high blood pressure, osteoporosis.(latest reports from Colorectal cancer 19,292 patients)

On Nov, 25, 2014: 31,007 people reported to have side effects when taking Actos. Among them, 41 people (0.13%) have Colorectal Cancer.

Trend of Colorectal cancer in Actos reports

Time on Actos when people have Colorectal cancer * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Colorectal cancer0.00%0.00%12.50%12.50%50.00%25.00%0.00%

Gender of people who have Colorectal cancer when taking Actos * :

FemaleMale
Colorectal cancer33.33%66.67%

Age of people who have Colorectal cancer when taking Actos * :

0-12-910-1920-2930-3940-4950-5960+
Colorectal cancer0.00%0.00%0.00%0.00%0.00%5.26%28.95%65.79%

Severity of Colorectal cancer when taking Actos ** :

leastmoderateseveremost severe
Colorectal cancer50.00%0.00%0.00%50.00%

How people recovered from Colorectal cancer ** :

while on the drugafter off the drugnot yet
Colorectal cancer50.00%0.00%50.00%

Top conditions involved for these people * :

  1. Prophylaxis (7 people, 17.07%)
  2. Colorectal cancer (7 people, 17.07%)
  3. Diabetes mellitus (7 people, 17.07%)
  4. Type 2 diabetes mellitus (7 people, 17.07%)
  5. Diabetes mellitus non-insulin-dependent (5 people, 12.20%)

Top co-used drugs for these people * :

  1. Glyburide (11 people, 26.83%)
  2. Lipitor (6 people, 14.63%)
  3. Aspirin (6 people, 14.63%)
  4. Panitumumab (6 people, 14.63%)
  5. Oxaliplatin (5 people, 12.20%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Colorectal Cancer while taking Actos?

You are not alone! Join a mobile support group:
- support group for people who take Actos and have Colorectal Cancer
- support group for people who take Actos
- support group for people who have Colorectal Cancer

Drugs in real world that are associated with:

Could your condition cause:

Can you answer these questions (Ask a question):

  • Is it normal getting pinpoint red spots when taking actos? what is the remedy?
    Dear Dr, im TTC, taking Actos, every time when taking im getting red spots which is slightly itching, is it normal, what should i do to get rid of them?
    Reply
  • My mother was given 4 prescriptions on 06/10/2013 and on the 28th, she passed away, would these have cased her liver and kidneys to shut down?
    we had went to er for a fall, where they did diagnostic xray, and she had bruised her butt, admitted due to small amt of fluid, everything seemed to be going downhill, come monday after thursday, liver and kidneys shut down, just two weeks prior, she was prescribed by her physician celebrex without lab work?
    Reply
  • Did all of these medications cause kidney failure and liver failure
    never had a liver diagnosis, took the celebrex for 1 week, and did not have blood work before subscribed, does any of these medications mixed cause problems?

    admitted for fall, discharged one week later to hospice
    Reply
  • Is there anyone who has information or experience with refractory multiple myeloma and the development of a second primary cancer in the colon (colon cancer)
    Diagnosed May 2009 with Stage IV, IGg Kappa Multiple Myeloma. Presented with pneumonia, 2 rib fractures, anemia, elevated serum m-protein, over 100 bone lesions, 78% plasma cells in bone marrow. No organ involvement. Chromosomal mutations, deletions, and transposition. Evaluated as low risk. 52 X-Y. After Revlamid-Dexamethazone induction therapy, Underwent Autogus Stem Cell Transplant involving Cytoxian based mobilization, High Dose Melphlain Chemotherapy. Had good response and well tolerated. Residual disease evident by residual ledic lesions and plasma cell involvement at 5%. Then consolidation therapy in the form of VDT-Pace, off protocall, that resulted in complete profound remission. After which began maintenance therapy of revlimid, valcade, dex. Time to disease progression of 30 months. Refractory to RVD maintenance. Began 3 cycles VDT-Pace plus Melphalan. Thus contributing to current good partial remission of 3 months. Now under new maintenance of pomalyst, dex,



    NOW, PET scan and follow-up colonscopy has confirmed a Second Primary Cancer discovered in the sigmoid colon as COLON CANCER. (super rare manifestation)



    Currently, under the care of one of the top in the field of Multiple Myeloma. And had, until now considered myself rather educated on this condition..... Now, I am searching for others, i.e. patients, caregivers or professionals willing to shed light on this otherwise unknown journey of which I am about to embark. Any onsite or direction would be greatly appreciates.... I guess I am #140 of 55,600 studied MM patients!!



    Thanks for your information and encouragement!!
    Reply
  • Is there a correllation between diphenhydramine usage and congestive heart failure?
    I have been a diabetic for 15 yrs, insulin dependent for 8 yrs. I was diagnosed with CHF in July of 2012. I have had two more episodes where I have decompensated, the most recent at the time of this writing (7/6). I took 2 doses of 50 mg Benadyl each about 4=5 hrs. apart. I was fine last night when I went to bed, having taken all of my other meds as prescribed. I woke up with difficulty breathing, coughing up large amounts of red to pink frothy sputum. An increased dose of furosemide (160 mgs , morning, afternoon, and evening seems to have mostly eliminated the wet lungs, but I am still weak. I did have a positive tilt, no LOC but very dizzy., with BP's around 123/76, resting pulse of 110. I am curious if the Benadryl could have contributed to this episode.
    Reply

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Comments from related drug studies (Check your drugs):

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  • Tingling and numbness in toes only and not severe. Started taking Revlimid on July 7, 2011, except for 10 weeks from 2-21-12 thru 5-1-12. Severe diarrhea has now occurred for about two years with no let up. I average about four times a day, starting in the AM. It usually tapers off after 2:00 PM ...
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  • Recently added actos and Losartan to my regiment of Prescription drugs and have recently noticed problems with achieving and sustaining erections. Prior to this, there was never a problem. I also take an aspirin, fish oil tablet and niacin capsule daily.
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  • I have had several hip operations. 1956 1979 1989 1999 2operations Not enough blood to my brain during last hip operation. 1999 Staff infection, severe. 1999 Have not drank or smoked in over 40 years.
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More related studies for: Actos, Colorectal cancer

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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