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Review: could Actos cause Diarrhea?

Summary: Diarrhea is found among people who take Actos, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Byetta, and have Type 2 diabetes.

We study 31,013 people who have side effects while taking Actos from FDA and social media. Among them, 1,270 have Diarrhea. Find out below who they are, when they have Diarrhea and more.

You are not alone: join a support group for people who take Actos and have Diarrhea >>>



Actos has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. (latest outcomes from 31,352 Actos users)


Diarrhea has been reported by people with high blood pressure, pain, depression, rheumatoid arthritis, osteoporosis. (latest reports from 139,378 Diarrhea patients)

On Apr, 18, 2015: 31,013 people reported to have side effects when taking Actos. Among them, 1,270 people (4.10%) have Diarrhea.

Trend of Diarrhea in Actos reports

Time on Actos when people have Diarrhea * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years

Gender of people who have Diarrhea when taking Actos * :


Age of people who have Diarrhea when taking Actos * :


Severity of Diarrhea when taking Actos ** :

leastmoderateseveremost severe

How people recovered from Diarrhea ** :

while on the drugafter off the drugnot yet

Top conditions involved for these people * :

  1. Type 2 diabetes mellitus (213 people, 16.77%)
  2. Diabetes mellitus non-insulin-dependent (212 people, 16.69%)
  3. Diabetes mellitus (208 people, 16.38%)
  4. Hypertension (86 people, 6.77%)
  5. Blood cholesterol increased (65 people, 5.12%)

Top co-used drugs for these people * :

  1. Byetta (381 people, 30.00%)
  2. Aspirin (316 people, 24.88%)
  3. Metformin hcl (259 people, 20.39%)
  4. Lisinopril (186 people, 14.65%)
  5. Lasix (171 people, 13.46%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of actos and diarrhea on

Do you have Diarrhea while taking Actos?




You are not alone! Join a support group on :
- support group for people who take Actos and have Diarrhea
- support group for people who take Actos
- support group for people who have Diarrhea

Drugs in real world that are associated with:

Could your condition cause:

Recent related drug studies (Check your drugs):

Recent Actos related drug comparison:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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