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Review: could Allopurinol cause Acute lymphocytic leukaemia?

Summary: Acute lymphocytic leukaemia could be caused by Allopurinol, especially for people who are female, 10-19 old, have been taking the drug for 1 - 6 months, also take Methotrexate, and have Acute lymphocytic leukaemia.

We study 50,490 people who have side effects while taking Allopurinol from FDA and social media. Among them, 35 have Acute lymphocytic leukaemia. Find out below who they are, when they have Acute lymphocytic leukaemia and more.

On Apr, 13, 2014: 50,490 people reported to have side effects when taking Allopurinol. Among them, 35 people (0.07%) have Acute Lymphocytic Leukaemia. They amount to 0.33% of all the 10,602 people who have Acute Lymphocytic Leukaemia on eHealthMe.

Trend of Acute lymphocytic leukaemia in Allopurinol reports

Time on Allopurinol when people have Acute lymphocytic leukaemia * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Acute lymphocytic leukaemia40.00%50.00%0.00%0.00%0.00%10.00%0.00%

Gender of people who have Acute lymphocytic leukaemia when taking Allopurinol * :

FemaleMale
Acute lymphocytic leukaemia53.66%46.34%

Age of people who have Acute lymphocytic leukaemia when taking Allopurinol * :

0-12-910-1920-2930-3940-4950-5960+
Acute lymphocytic leukaemia0.00%3.57%28.57%0.00%21.43%10.71%7.14%28.57%

Severity of Acute lymphocytic leukaemia when taking Allopurinol ** :

n/a

How people recovered from Acute lymphocytic leukaemia ** :

n/a

Top conditions involved for these people * :

  1. Acute lymphocytic leukaemia (16 people, 45.71%)
  2. Tumour lysis syndrome (9 people, 25.71%)
  3. Prophylaxis (4 people, 11.43%)
  4. Gastrostomy tube insertion (4 people, 11.43%)
  5. Pyrexia (4 people, 11.43%)

Top co-used drugs for these people * :

  1. Methotrexate (13 people, 37.14%)
  2. Dexamethasone (13 people, 37.14%)
  3. Vincristine (12 people, 34.29%)
  4. Ondansetron (10 people, 28.57%)
  5. Acetaminophen (9 people, 25.71%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Allopurinol, Acute lymphocytic leukaemia

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On eHealthMe, Allopurinol (allopurinol) is often used for gout. Find out below the conditions Allopurinol is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

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Comments from related studies:

  • From this study (4 days ago):

  • peripheral neuropathy intermittent and have just begun to reduce metoprolol succinate 100mg to 50mg while trying to eliminate drug totally

    Reply

  • From this study (3 weeks ago):

  • I am curious to know if the Allopurinol can increase blood sugar, though I gained up to 10 lbs since I first started taking this med, I think in part due to less exercise on my part.

    Reply

  • From this study (4 weeks ago):

  • I have NASH related Cirrhosis, Asthma, COPD, Narcolepsy, OSA/Hypopnea, RLS, Type II Diabetes along with Factor V. I take 300mg of Allopurinol daily and was just increased to 60mg of Ritalin.

    Reply

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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