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Review: could Allopurinol cause Edema (Swelling)?





Summary: Edema is found among people who take Allopurinol, especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years, also take medication Zometa, and have Gout.

We study 50,559 people who have side effects while taking Allopurinol from FDA and social media. Among them, 405 have Edema. Find out below who they are, when they have Edema and more.

You are not alone: join a mobile support group for people who take Allopurinol and have Edema >>>

Allopurinol

Allopurinol has active ingredients of allopurinol. It is often used in gout. (latest outcomes from Allopurinol 51,438 users)

Edema

Edema (excess of watery fluid collecting in the cavities or tissues of the body) has been reported by people with high blood pressure, pain, rheumatoid arthritis, osteoporosis, metastases to bone.(latest reports from Edema 21,478 patients)

On Nov, 25, 2014: 50,550 people reported to have side effects when taking Allopurinol. Among them, 367 people (0.73%) have Edema.

Trend of Edema in Allopurinol reports

Time on Allopurinol when people have Edema * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Edema29.41%11.76%0.00%47.06%5.88%5.88%0.00%

Gender of people who have Edema when taking Allopurinol * :

FemaleMale
Edema51.37%48.63%

Age of people who have Edema when taking Allopurinol * :

0-12-910-1920-2930-3940-4950-5960+
Edema0.00%0.00%0.00%0.33%1.00%5.98%35.55%57.14%

Severity of Edema when taking Allopurinol ** :

leastmoderateseveremost severe
Edema0.00%40.00%60.00%0.00%

How people recovered from Edema ** :

while on the drugafter off the drugnot yet
Edema0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Gout (72 people, 19.62%)
  2. Multiple myeloma (67 people, 18.26%)
  3. Anxiety (36 people, 9.81%)
  4. Osteoporosis (36 people, 9.81%)
  5. Metastases to bone (35 people, 9.54%)

Top co-used drugs for these people * :

  1. Zometa (167 people, 45.50%)
  2. Aredia (152 people, 41.42%)
  3. Aspirin (135 people, 36.78%)
  4. Lasix (93 people, 25.34%)
  5. Prilosec (87 people, 23.71%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Edema while taking Allopurinol?

You are not alone! Join a mobile support group:
- support group for people who take Allopurinol and have Edema
- support group for people who take Allopurinol
- support group for people who have Edema

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More questions for: Allopurinol, Edema

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    I take allopurinol on a purely prophylactic basis, as my father has got gout and kidney stones. Since three months I suffer from achilles tendinitis; I put it down to overload; I am rather heavy and play a lot of tennis, besides moving a lot at work. As always, I tried to "walk through" my weight associated problems, but it did not get any better. Non-compliant, I stopped taking allopurinol for the last three days, and, surprise surprise, the pain is quickly abating, in spite of playing prolonged matches the last three days. I remembered that gyrase inhibitors (e.g. ciprofloxacin) predispose to achilles tendon rupture, a fact that I was personal witness with a female player at our club. So I speculate on a causal link between allopurinol and achilles tendinitis
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    After 1 week of Allopurinol, I had to discontinue the drug due to debilitating nausea, which was worst in the morning.
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    I have just been prescribed 100mg Allopurinol.
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    I am in my second day of taking these tablets.
    I have begun to get get a sudden pain in my ear.
    I have never in all my years have ever had such a pain.
    I know the only change that has happened around me is taking these tablets.
    I have stopped taking these and am awaiting my next appt with my GP.
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  • Bone pain localized to poison ivy rash
    I am having a moderate to strong reaction to poison ivy exposure. I have a localized rash with blistering, swelling and inflammation similar to cellulitis. The rash has been progressing for about a week. The blisters are not weeping or oozing. The area is cleaned daily with neem oil soap. Coincident with the rash, I have a persistent ache/pain in my lower forearm, wrist and hand that is responding weakly to Aleve and pretty much unresponsive to acetaminophen.
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  • Allopurinol and muscle cramps
    Approximately 5 years ago I developed gout and my physician prescribed allopurinol. After a period of time I began to have muscle spasms in the calves of my legs at night. My doctor gave me a prescription for restless leg syndrome, which helped for a short time. I was then given a different prescription when that one no longer helped, and finally a third prescription, which did not work either. The cramps continued to grow more severe and more frequent. I was also having extremely severe cramps in my left hand, to the point that I could not straighten my fingers for several excruciating minutes. Although the cramps in my calves had lessened significantly, my toes were starting to cramp severely.



    I stopped taking allopurinol about a month ago, and since then I realized that my hands and toes were cramping less and less, and now it is almost completely gone. I inadvertently stopped the allopurinol and I lost the bottle of pills and didn't realize it until I went to refill my pill box that holds a month's supply divided into daily doses. I searched on the internet and found that muscle problems are not uncommon for some people taking allopurinol.
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More reviews for: Allopurinol, Edema

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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