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Review: could Allopurinol cause Edema?

We study 50,512 people who have side effects while taking Allopurinol from FDA and social media. Among them, 367 have Edema. Find out below who they are, when they have Edema and more.

Stay connected: get help anytime and anywhere for people who take Allopurinol and have Edema >>>

Allopurinol

Allopurinol (latest outcomes from 51,389 users) has active ingredients of allopurinol. It is often used in gout.

Edema

Edema (excess of watery fluid collecting in the cavities or tissues of the body) (latest reports from 181,237 patients) has been reported by people with high blood pressure, rheumatoid arthritis, pain, osteoporosis, metastases to bone.

On Jul, 14, 2014: 50,509 people reported to have side effects when taking Allopurinol. Among them, 367 people (0.73%) have Edema. They amount to 0.20% of all the 181,203 people who have Edema on eHealthMe.

Trend of Edema in Allopurinol reports

Time on Allopurinol when people have Edema * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Edema29.41%11.76%0.00%47.06%5.88%5.88%0.00%

Gender of people who have Edema when taking Allopurinol * :

FemaleMale
Edema51.37%48.63%

Age of people who have Edema when taking Allopurinol * :

0-12-910-1920-2930-3940-4950-5960+
Edema0.00%0.00%0.00%0.33%1.00%5.98%35.55%57.14%

Severity of Edema when taking Allopurinol ** :

leastmoderateseveremost severe
Edema0.00%40.00%60.00%0.00%

How people recovered from Edema ** :

while on the drugafter off the drugnot yet
Edema0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Gout (72 people, 19.62%)
  2. Multiple myeloma (67 people, 18.26%)
  3. Anxiety (36 people, 9.81%)
  4. Osteoporosis (36 people, 9.81%)
  5. Metastases to bone (35 people, 9.54%)

Top co-used drugs for these people * :

  1. Zometa (167 people, 45.50%)
  2. Aredia (152 people, 41.42%)
  3. Aspirin (135 people, 36.78%)
  4. Lasix (93 people, 25.34%)
  5. Prilosec (87 people, 23.71%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Comments from related studies:

  • From this study (7 days ago):

  • Also have decreased kidney function 25% of kidneys are functioning. When I went in the hospital in May 2014 , 2 small blood clots were found ( lung and also in right leg ) Plus I had Gout and continued to have pain in the knee and swelling in right leg. Now I am ok, but still taking 5 mg of prednisone (for a 10 day period) I was taking prednisone while in the hospital as well and after when I returned home continued. I went to the Rheumatologist and he didnt like the way the hospital dispensed the medication. (He said it took too long the way it had been prescribed) So he told me not to continue it that way and to follow it his way so he increased the dosage to 40 mg and then tapered to 20 and then to 10 mg. off for a total 6 days, but i was still in pain in my knee and swelling. He told me to continue for a 10 day period 5 mg. but i still had some pain and swelling. He told me to do another 10 day period with 5 mg . The reason is I had to be attack free in order to start my 50 mg of Allopurinol 3 times a week which I started today. I dont have any pain in my right leg but it still swells a little when I am walking a lot, but when I elevate it, swelling goes down and leg is normal. At night, I sleep with a pillow under my legs which helps. The other thing is my kidney doctor wants to put me on Calcitriol (Vit. D) He wants to do this in September and I want to know is this ok to take because of my "decreased kidney function"? My calcium blood level is 9.0 right now and previous blood reports Calcium levels were 9.2, 8.6, 9.4 and 9.1 Wouldnt this be considered a normal calcium level. I understand that too much calcium in the blood is not good. I also wanted to mention that I have high blood pressure for many years and when I went in the hospital, they took me off the High blood pressure medication Quinapril (20 mg) and I am still off it. I lost 15 lbs and BP pressure is about 130/70 but eventually Dr. wants to put me back on it. As for the Hyperparathyroidism which was was shown on my last blood test that i took. Is it possible that the Prednisone that I have been taking could have caused this? I appreciate any help you can give me on the above. Thank you.

    Reply

  • From this study (1 week ago):

  • I keep having an allergic reaction while ONLY in my apartment. I've had these symptoms with (worsening over time) since moving in. I would like to know if I have a possible mold allergy because my place is very old and has no ventilation.

    My symptoms such as the swelling, edema, throat tightness, and trouble breathing all go away within forty minutes of leaving my apartment and return within thirty minutes of being home. I also have greater mental clarity while away from home. I would like to pinpoint what is making me react. I own two cats, but I have never reacted to them before.

    My symptoms with the swelling also worsen upon eating soy sauce, cheese, or when I add salt, which has never been an issue until the recent weeks, about the time my throat started mildly closing. Soy sauce made my ankles triple in size for three days, as well as my calves and feet. I couldn't bend my toes or fit my shoes and I had difficulty breathing and strange tingling in my calves and ankles. I have never even mildly swollen from any foods in my life.

    I have only tried Zyrtec and Claritin. Zyrtec keeps away all the swelling, but Claritin doesn't. Claritin did help me with my dog allergy, but it is not with whatever is going on in my apartment.

    Reply

    kathym on Jun, 23, 2014:

    Probably either toxic mold or pesticides you should move. Wish it was better news. I've had MCS for 17 yrs and if you don't do something about your situation you may have permanent damage to your immune system.

    Reply

  • From this study (1 week ago):

  • During exertion, experience shortness of breath and burning in leg muscles. Observed low heart rate.

    Reply

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More reviews for: Allopurinol, Edema

On eHealthMe, Allopurinol (allopurinol) is often used for gout. Find out below the conditions Allopurinol is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

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