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Review: could Allopurinol cause Vasculitis?

Summary: Vasculitis is found among people who take Allopurinol, especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years, also take medication Aspirin, and have Osteoporosis.

We study 50,579 people who have side effects while taking Allopurinol from FDA and social media. Among them, 137 have Vasculitis. Find out below who they are, when they have Vasculitis and more.

You are not alone: join a mobile support group for people who take Allopurinol and have Vasculitis >>>

 

 

 

 

Allopurinol

Allopurinol has active ingredients of allopurinol. It is often used in gout. (latest outcomes from 51,464 Allopurinol users)

Vasculitis

Vasculitis (inflammation of a blood vessel or blood vessels) has been reported by people with rheumatoid arthritis, high blood pressure, osteoporosis, multiple sclerosis, depression. (latest reports from 8,109 Vasculitis patients)

On Feb, 28, 2015: 50,579 people reported to have side effects when taking Allopurinol. Among them, 137 people (0.27%) have Vasculitis.

Trend of Vasculitis in Allopurinol reports

Time on Allopurinol when people have Vasculitis * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Vasculitis30.00%20.00%0.00%0.00%50.00%0.00%0.00%

Gender of people who have Vasculitis when taking Allopurinol * :

FemaleMale
Vasculitis42.03%57.97%

Age of people who have Vasculitis when taking Allopurinol * :

0-12-910-1920-2930-3940-4950-5960+
Vasculitis0.00%0.00%0.00%0.77%0.77%3.08%42.31%53.08%

Severity of Vasculitis when taking Allopurinol ** :

n/a

How people recovered from Vasculitis ** :

n/a

Top conditions involved for these people * :

  1. Osteoporosis (29 people, 21.17%)
  2. Systemic lupus erythematosus (24 people, 17.52%)
  3. Gout (19 people, 13.87%)
  4. Thrombocytopenia (12 people, 8.76%)
  5. Multiple myeloma (10 people, 7.30%)

Top co-used drugs for these people * :

  1. Aspirin (40 people, 29.20%)
  2. Lasix (33 people, 24.09%)
  3. Diflucan (33 people, 24.09%)
  4. Prednisone (32 people, 23.36%)
  5. Vancomycin (30 people, 21.90%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Allopurinol and vasculitis on

Do you have Vasculitis while taking Allopurinol?

You are not alone! Join a mobile support group:
- support group for people who take Allopurinol and have Vasculitis
- support group for people who take Allopurinol
- support group for people who have Vasculitis

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You may be interested at these reviews (Write a review):

  • AllopĆ¼rinol and achilles tendinitis
    I take allopurinol on a purely prophylactic basis, as my father has got gout and kidney stones. Since three months I suffer from achilles tendinitis; I put it down to overload; I am rather heavy and play a lot of tennis, besides moving a lot at work. As always, I tried to "walk through" my weight associated problems, but it did not get any better. Non-compliant, I stopped taking allopurinol for the last three days, and, surprise surprise, the pain is quickly abating, in spite of playing prolonged matches the last three days. I remembered that gyrase inhibitors (e.g. ciprofloxacin) predispose to achilles tendon rupture, a fact that I was personal witness with a female player at our club. So I speculate on a causal link between allopurinol and achilles tendinitis
  • Allopurinol for 6-mp metabolism to 6-tgn
    I began taking Allopurinol 100mg to help metabolize the Purinethol I have been taking for 6 years for Crohn's disease after a blood test revealed my 6-MMP metabolites were too high and 6-TG were too low. Several published studies show Allopurinol to be helpful for "non-preferential metabolizers" like me, to help shunt the metabolic pathway towards therapeutic 6-TG.

    After 1 week of Allopurinol, I had to discontinue the drug due to debilitating nausea, which was worst in the morning.
  • Ear pain from allopurinol 100mg (1 response)
    I have just been prescribed 100mg Allopurinol.
    1 a day.
    I am in my second day of taking these tablets.
    I have begun to get get a sudden pain in my ear.
    I have never in all my years have ever had such a pain.
    I know the only change that has happened around me is taking these tablets.
    I have stopped taking these and am awaiting my next appt with my GP.
    I do take Arcoxia with paracetemol for pain relief.
  • Allopurinol and muscle cramps
    Approximately 5 years ago I developed gout and my physician prescribed allopurinol. After a period of time I began to have muscle spasms in the calves of my legs at night. My doctor gave me a prescription for restless leg syndrome, which helped for a short time. I was then given a different prescription when that one no longer helped, and finally a third prescription, which did not work either. The cramps continued to grow more severe and more frequent. I was also having extremely severe cramps in my left hand, to the point that I could not straighten my fingers for several excruciating minutes. Although the cramps in my calves had lessened significantly, my toes were starting to cramp severely.



    I stopped taking allopurinol about a month ago, and since then I realized that my hands and toes were cramping less and less, and now it is almost completely gone. I inadvertently stopped the allopurinol and I lost the bottle of pills and didn't realize it until I went to refill my pill box that holds a month's supply divided into daily doses. I searched on the internet and found that muscle problems are not uncommon for some people taking allopurinol.
  • Avelox with prednisone and nabumetome = disaster
    I was prescribed that combination of drugs in January 2013 when I went to my family doctor with a bad chest congestion and painful knees. After starting on the drugs, I got a severely painful neck and thumb and noticed some tingling in my left foot. I took the whole course of the avelox and prednisone, though I discontinued the nabumetome. I kept getting weaker and weaker till I could hardly walk. I ended up in the emergency room and was first diagnosed with Rhabdomyolysis but rushed to a bigger hospital for further diagnosis and treatment. I was close to needing blood, my kidneys were shutting down and I could barely walk. I was so weak! My right hand and left foot went "to sleep" and still haven't woken up. ( as of October 2013)

    After many, many tests, they came up with a tentative diagnosis of vasculitis and myositis.

    Then I had a kidney biopsy which confirmed the vasculitis and I was immediately treated with chemotherapy -- cytoxin for 6 months.

    IAlthough I do feel much better, I am still suffering and taking drugs for the vasculitis and I am told that I may go into remission, but it could flare up again anytime. I am convinced that it was the drug combination that caused all this. I had been feeling great and had a daily walking routine of walking 2 to 5 miles per day, and no other complaints.

    The nephrologist did say that while it might be that the vasculitis was drug induced, it didn't matter because I have it and he's treating it and would be doing it this way no matter how I got it.

    When I told my family doctor that I thought it was the drug combination that caused my problems, he seemed surprised and really no discussion. I told them to put it in my medical records to NEVER give me a flouroquinolone drug again.

    Yesterday when I went for a blood test and urinalysis ( which I was doing biweekly, but now every 6 weeks), it showed that I have a UTI and guess what the family doctor called in a prescription for? Cipro!!!! And he knows I'm still on prednisone and have only 30% kidney function!!!!!!

    While I am not a litigious person, this really makes me so upset!!! I don't have the money to try to sue, but if telling my story will help keep unsuspecting people from the horrible damage this has caused, I feel obligrdmtomspeak up. I have had a terrible year. And I'm still not okay. And the drugs 'm taking make me susceptible to other problems. I'm still all puffed up from the prednisone. A couple of weeks ago I decided to try going for walks again, hopefully to lose some of this weight and build up my strength. It is so hard for me and my left foot hurts so bad. My legs feel so heavy it is a real struggle to walk a mile. But at least I can. When I was at my sickest, could barely walk to the bathroom and I could not get up from the toilet without using my arms to pull myself up. I couldn't go up the two steps to get into my house without help. I couldn't go upstairs to my bedroom for months.

More reviews for: Allopurinol, Vasculitis

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