Review: could Allopurinol cause Water retention (Fluid Retention)?
Summary: Water retention is found among people who take Allopurinol, especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months, also take medication Aspirin, and have Multiple myeloma.
We study 50,566 people who have side effects while taking Allopurinol from FDA and social media. Among them, 265 have Water retention. Find out below who they are, when they have Water retention and more.
You are not alone: join a mobile support group for people who take Allopurinol and have Water retention >>>
Allopurinol has active ingredients of allopurinol. It is often used in gout. (latest outcomes from 51,452 Allopurinol users)
Water retention (an abnormal accumulation of fluid in the blood) has been reported by people with primary pulmonary hypertension, high blood pressure, diabetes, type 2 diabetes, osteoporosis. (latest reports from 18,400 Water retention patients)
On Jan, 18, 2015: 50,566 people reported to have side effects when taking Allopurinol. Among them, 265 people (0.52%) have Water Retention.
Time on Allopurinol when people have Water retention * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Water retention||0.00%||0.00%||66.67%||0.00%||33.33%||0.00%||0.00% |
Gender of people who have Water retention when taking Allopurinol * :
|Water retention||33.70%||66.30% |
Age of people who have Water retention when taking Allopurinol * :
|Water retention||0.00%||0.00%||0.42%||0.00%||3.39%||8.90%||23.73%||63.56% |
Severity of Water retention when taking Allopurinol ** :
|least||moderate||severe||most severe |
|Water retention||0.00%||100.00%||0.00%||0.00% |
How people recovered from Water retention ** :
Top conditions involved for these people * :
- Multiple myeloma (20 people, 7.55%)
- Pain (15 people, 5.66%)
- Chronic myeloid leukaemia (15 people, 5.66%)
- Gout (15 people, 5.66%)
- Hyperuricaemia (12 people, 4.53%)
Top co-used drugs for these people * :
- Aspirin (72 people, 27.17%)
- Lasix (65 people, 24.53%)
- Furosemide (57 people, 21.51%)
- Potassium chloride (36 people, 13.58%)
- Digoxin (33 people, 12.45%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you have Water Retention while taking Allopurinol?
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I take allopurinol on a purely prophylactic basis, as my father has got gout and kidney stones. Since three months I suffer from achilles tendinitis; I put it down to overload; I am rather heavy and play a lot of tennis, besides moving a lot at work. As always, I tried to "walk through" my weight associated problems, but it did not get any better. Non-compliant, I stopped taking allopurinol for the last three days, and, surprise surprise, the pain is quickly abating, in spite of playing prolonged matches the last three days. I remembered that gyrase inhibitors (e.g. ciprofloxacin) predispose to achilles tendon rupture, a fact that I was personal witness with a female player at our club. So I speculate on a causal link between allopurinol and achilles tendinitis
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I have just been prescribed 100mg Allopurinol.
1 a day.
I am in my second day of taking these tablets.
I have begun to get get a sudden pain in my ear.
I have never in all my years have ever had such a pain.
I know the only change that has happened around me is taking these tablets.
I have stopped taking these and am awaiting my next appt with my GP.
I do take Arcoxia with paracetemol for pain relief.
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- Allopurinol and muscle cramps
Approximately 5 years ago I developed gout and my physician prescribed allopurinol. After a period of time I began to have muscle spasms in the calves of my legs at night. My doctor gave me a prescription for restless leg syndrome, which helped for a short time. I was then given a different prescription when that one no longer helped, and finally a third prescription, which did not work either. The cramps continued to grow more severe and more frequent. I was also having extremely severe cramps in my left hand, to the point that I could not straighten my fingers for several excruciating minutes. Although the cramps in my calves had lessened significantly, my toes were starting to cramp severely.
I stopped taking allopurinol about a month ago, and since then I realized that my hands and toes were cramping less and less, and now it is almost completely gone. I inadvertently stopped the allopurinol and I lost the bottle of pills and didn't realize it until I went to refill my pill box that holds a month's supply divided into daily doses. I searched on the internet and found that muscle problems are not uncommon for some people taking allopurinol.
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Comments from related studies:
From this study (4 weeks ago):
lab results show elevated BUN and Creatinine and elevated serum calcium
From this study (2 months ago):
I have been taking allopurinol (300mg) since 1990 and blood tests indicate an increase in serum ferritin from 288 to 410 ug/l over the past 18 months. I used to be a blood donor but have stopped since prostate cancer treatment four years ago.
From this study (3 months ago):
Triggered when I play golf when the temp is above 78-80 degrees.
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