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Review: could Aloe vera cause Peripheral edema?

Summary: Peripheral edema could be caused by Aloe vera, especially for people who are female, 60+ old, also take Humira, and have Hypertension.

We study 98 people who have side effects while taking Aloe vera from FDA and social media. Among them, 8 have Peripheral edema. Find out below who they are, when they have Peripheral edema and more.

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Aloe vera

Aloe vera (latest outcomes from 111 users) has active ingredients of aloe.

On Apr, 9, 2014: 97 people reported to have side effects when taking Aloe vera. Among them, 8 people (8.25%) have Peripheral Edema. They amount to 0.00% of all the 616,672 people who have Peripheral Edema on eHealthMe.

Trend of Peripheral edema in Aloe vera reports

Time on Aloe vera when people have Peripheral edema * :


Gender of people who have Peripheral edema when taking Aloe vera * :

Peripheral edema77.78%22.22%

Age of people who have Peripheral edema when taking Aloe vera * :

Peripheral edema0.00%0.00%0.00%0.00%0.00%0.00%0.00%100.00%

Severity of Peripheral edema when taking Aloe vera ** :


How people recovered from Peripheral edema ** :


Top conditions involved for these people * :

  1. Hypertension (5 people, 62.50%)
  2. Vitamin supplementation (4 people, 50.00%)
  3. Psoriasis (3 people, 37.50%)
  4. Pruritus (3 people, 37.50%)
  5. Insomnia (2 people, 25.00%)

Top co-used drugs for these people * :

  1. Humira (5 people, 62.50%)
  2. Omeprazole (3 people, 37.50%)
  3. Norco (3 people, 37.50%)
  4. Levothyroxine sodium (3 people, 37.50%)
  5. Triamterene and hydrochlorothiazide (3 people, 37.50%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Aloe vera, Peripheral edema

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  • Carol-51 on Feb, 5, 2014:

    I am a 79 year old female who has been taking tramadol (prescribed by my Rheumetolgist) for about one month. Reently my feet and ankles started swelling. I could find nothing in the side effects of tramadol to cause this. I do have kidney disease but my family Dr. checks on this every 6 mo. and my last test four months ago was "a little high" but not enough to refer me to a kidney specialist. I'm going to stop the tramadol for a while to see what happens.


    schorel on Dec, 7, 2013:

    I also took this medication for 2 weeks. I had a pretty severe reaction leading to swollen feet, ankles, legs and from my elbows down to my fingers. My doctor also dismissed that it was due to this med even though I have NEVER had this happen to me. He gave me lasix to flush it out of my body and hydrocodone for pain. My question is how long did you experience these symptoms? It is unbearable!!! How long did yours last? Anything you could tell me to help me would be greatly appreciated.


    Rebecca VanGorder on Apr, 3, 2011:

    I started taking Tramadol 5 times a day per my Rhuematologist. Within 2 weeks I couldn't even get my shoes on, my calves legs and feet were so swollen. I ask my pharmacist, my primary care doctor and Rhuematologist and they said they had never heard of swelling due to Tramadol use.
    I can tell you personally if they had known of this and informed me when I told them it would have saved me 3 doctors visits and alot of pain.
    I found out by myself I stopped using the Tramadol and within a few days noticed the swelling starting to go down. The people who make Tramadol should make this known as a side effect of Tramadol as no one seems to know this accept people who get it.


    ter218 on Feb, 8, 2013:

    Same here.....terrible water retention in feet ankles from Tramadol. My doctor never equated the meds and the edema...but when I stop taking the meds the swelling goes down.


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Can you answer these questions (what is this?):

  • Is taking imodium a few days after taking aloe vera gel safe?
    I have diarrhea from taking aloe Vera gel and I really need to get rid of it, I bought the aloe Vera gel on about Monday of this week. I have been having diarrhea from this aloe Vera gel since a day after I took it. I was wondering if it was safe to take Imodium for my diarrhea four days after i dra ...

More questions for: Aloe vera, Peripheral edema

More reviews for: Aloe vera, Peripheral edema

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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- Aloe Vera side effects


Related symptom

- Peripheral Edema



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