Review: could Ambien cause Irritability?
Summary: Irritability is found among people who take Ambien, especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months, also take medication Oxycontin, and have Depression.
We study 43,150 people who have side effects while taking Ambien from FDA and social media. Among them, 470 have Irritability. Find out below who they are, when they have Irritability and more.
You are not alone: join a mobile support group for people who take Ambien and have Irritability >>>
Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. (latest outcomes from 46,757 Ambien users)
Irritability has been reported by people with depression, quit smoking, pain, stress and anxiety, attention deficit hyperactivity disorder. (latest reports from 23,559 Irritability patients)
On Feb, 13, 2015: 43,135 people reported to have side effects when taking Ambien. Among them, 470 people (1.09%) have Irritability.
Time on Ambien when people have Irritability * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
Gender of people who have Irritability when taking Ambien * :
Age of people who have Irritability when taking Ambien * :
Severity of Irritability when taking Ambien ** :
|least||moderate||severe||most severe |
How people recovered from Irritability ** :
|while on the drug||after off the drug||not yet |
Top conditions involved for these people * :
- Depression (105 people, 22.34%)
- Pain (92 people, 19.57%)
- Insomnia (88 people, 18.72%)
- Anxiety (62 people, 13.19%)
- Sleep disorder (42 people, 8.94%)
Top co-used drugs for these people * :
- Oxycontin (128 people, 27.23%)
- Xanax (104 people, 22.13%)
- Lortab (80 people, 17.02%)
- Paxil (75 people, 15.96%)
- Celebrex (68 people, 14.47%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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- Blepharospasm caused by zolpidem
Used for three years before I started to develop blepharospasm.
- Yaz was the cause of increasing my pmdd, pms, irritability and depression symptoms
I had taken Ortho Novum 777 from the age of 18 to 28 stopping in-between pregnancies. I had 3 children between the ages of 21 and 29.
In my early 30's I decided to stop taking birth control pills simply because I 'thought' it would be a healthier thing to do for my body. I did know that unless I was taking Ortho Novum that my period were not the standard 28 day routine. They were irregular and would be anywhere from 28 to 38 days. The longer the time in between periods the worse the pms symptoms would be. My theory is most likely because of the extended time between when I perceived a period and when I actually got it. It could very well have been psychosomatic but when my period would finally arrive, irritability and bloating would subside within a day or two. It was like a reset button and relief. I was calmer, more rational, even Kiel and motivated.
In addition to the irregular pattern of my periods when off if birth control pills I also experienced pms twice a month. It would happen mid month when I was ovulating. The ovulation would be uncomfortable, I'd feel bloated again, and the cramps were painful. I'd move from ovulation week of irritability to PMS week of even greater irritability. I'd be waiting and counting down til my period was suppose to happen in anticipation of relief.
I remember age 32 being significant for some reason. Upon reflecting back over the years while seeking treatment for a solution out of the psyco cycle I remember referring to age 32 as the year that things were never the same as they were in my 20's.
Mid 30's I had asked my ob/gyn if I could go back on the Ortho Novum 777. I was told that I was too old. This was early 2000's, 2003 or 2004. I was given a different birth control pill that he recommended and I tried that for a while but it wasn't making things better and I don't remember the exact details. I tried bio identical hormones... That wasn't really helpful either, it was more work and a long process that I stuck with for at least a year trying to get the formula right. I finally threw the towel in on that.
Then a different ob/gyn suggested I try progesterone only. He prescribed a pink round ball of a pill. I was to take it the last 10 days of the month. I tried that for 3 or 4 months, it wasn't making things better... in fact I think it made it worse. Then I went cold turkey again for the better part of a year. At age 37, after not finding a doctor that was helping the situation I decided to find a doctor in AZ. I live full time in CA but had a vacation home in AZ so I thought I'd try that for a change.
I did find a doctor and she prescribed yaz 24 day. She said it should help me as it has helped many other women. I took the yaz for a little better than a year and psychologically I thought I had a winner! This doctor sounded like she knew my problems and that this was the solution. Alas it was not. I remember feeling the most depressed is ever felt. I didn't think it had anything to do with the yaz, I figured it was just life. When I returned to that doctor after a year I explained my situation. She then recommended that I get an ablation!?! I was never a heavy bleeder and it makes no sense to have that done, but she sold me on the idea that it would help my problem. I realize now she was doing exactly that, selling. I'm sure it was a nice payment from the insurance company.
None of my issues were solved. I had stopped taking the yaz or any birth control at that point. My period were non existent after boiling my uterus in boiling water, which is what the ablation is. And to this day my period is hardly worth talking about or being prepared for. It's spotting for a couple 3 days at best. With regard to my symptoms, the pms, pmdd, extreme irritability, depression all that stayed the same. I tried Seasonal for about 2 months and that was not good, it seemed to 'amp' the 'hot' - not physically hot but an irritable term I use to describe the upped level my nerves set at.
I did exercise pretty regularly during all if this. The times I wasn't exercising were over the top as far as pmdd symptoms so that motivates you to get your rear to the gym. On the Yaz 24 day I knew something wasn't right. At day 14 I'd feel the symptoms if ovulation, not imagined but real. I was slightly irritable and had cramps for 2 to 3 days. At day 17, a Wednesday the irritability would ramp up and the depression would start to be present for the next 2 weeks.
The following Wednesday was day 24, that was the last day of taking the pill. I did get a bit of relief after stopping the pill and 4 days later I resumed taking the next months pack on Sunday. The thing is I wouldn't get my period until Tuesday after I started the new pack? I know that my period should have happened between day 24 and 28 but it never did. It always started on day 31 or 32 and lasted 2 to 3 days. Then the whole cycle begins again with day 14.
On Yaz 24
Day 1 Sunday
Day 3 or 4 Tuesday and my period would start.
Day 5 or 6 my period ended
Day 14 - Day 17 ovulation type cramping
Day 17 irritability started ramping up into PMS, PMDD & Depression
Symptoms were worse without exercise by at least 40%
Day 24 Wednesday, last day of Yaz pack for the month
Day 25 slight mood improvement
Day 30-31 (same as Day 3/4above) period would start
The ob/gyn expertise wasn't working, male or female. I went to my regular general practitioner for a check up and had done much research on the type of hormones in the Yaz, Yasmin and many others. I was convinced that I need to move over to Yasmin 21 day. It had a but more estrogen and it was only 21 instead of 24 days so worth a try.
She asked me when the last time I felt 'normal' with regard to the hormones. I told her that as far as I can recall it was when I was in my 20's when I was taking the Ortho Novum 777. She said why don't we have you start taking that again! I was like, what? I explained I was told I could not take that because of my age and I thought some doctor had told me it had been discontinued years ago anyway. She said no, I can prescribe it to you, it's still available. I was a little excited about that. Maybe... just maybe that would be a solution for relief. My blood pressure is 100/70 always has been low, I don't smoke and I'm 5' 8", 150 pounds. She saw no reason for me not to try it again. We agreed that I would and if it didn't go well we'd try the Yasmin.
I've been in the Ortho Novum, my package and brand saying Alyacen 7/7/7 for 3 weeks now. Today is Sunday and I stop taking active pills for 7 days now. At day 7 or so I noticed how much easier it was becoming to get out of bed in the morning. I began noticing I had an interest in getting something done. I didn't have a big heavy cloud urging me to just stay in bed. I started feeling alive again.
The jury is still out and I have ordered a second months supply but I am deeply encouraged. During week 3 I have been crampier than on the yaz but in a very normal feeling way. Like my body is preparing for menstruation. I'm anticipating bleeding heavier than I'm used to, but in a good way. The cramping has been something I definitely notice much much more so but it's manageable. What I also notice is lack...... huge overwhelming lack of that horrible irritability. I'm more sensitive than weeks one and two but it's nothing by comparison. I've been more level headed, more 'normal'. Time will tell if this is my cure for the next 6 or so years but I'm extremely encouraged right now. I literally feel the best I have in years and there is some pretty crapy stressful things going on in my life. But I can handle them-
Side note, I am a Type A personality. I am under a lot of stress running my own business often. I am a mother of 3 and a very capable woman. Watch out world if I'm back like my 20's nothing will stop me. I'm positive, excited and thankful for this moment.
It stinks if this is this truly is the solution to my problem, as years of my life and those around me have been effected. But it does no good to look back I'm looking forward with great anticipation!
Good Luck, I hope this monologue can help someone else just like me and I'll be saving a copy for future female generations of mine.
- Zolpidem er side effects
I was in this medicaion for 2 weeks.I had severe headache,muscular backache and a rash in one side of my body.I didn't had problems falling asleep but I had problems staying asllep.I will switch to Lunesta 3mg.
- I need advise, badly ckd!! (1 response)
The orthostatic BP started in mid April, I was only dizzy upon wakening then it would subside. I have never been a big breakfast eater so I started doing that. We were in Disney later in April and I was extremely fatigued, to the point of not wanting to walk, Disney would be the first time I passed out when getting dizzy. I of course said I had gotten too warm and was exhausted from work the previous week. The dizziness continued in the mornings & I passed out several more times. On May 1st, I passed out while putting my make-up on and hit my eye on the faucet and head on the tile floor, despite that I went to work thinking it would subside, it didn't. I went to the ER directly after work. They ran a B-met on me and my GFR was 11 and creatinine 3.95. They admitted me to a larger hospital for evaluation. While in there, they pumped me with fluids continuously, saying I had severe dehydration. My kidney function improved, my creatinine levels went back down to 1.34. After 5 days I was discharged and told to see a cardiologist and endo. The endo doc cancelled my appointment on the basis it was not his area. I had had a cortisol and ACTH testing which I guess was normal. I saw the cardiologist, who said it wasn't cardio. I had had an echocardiogram in the hospital and EKG monitoring. Cardio sent me to neurology, the PNRN did a basic neurological exam and drew blood for disease markers such as Lupus, sjorgens, hepatitis, ect. All disease markers came back negative, but my GFR was at 11 again and creatinine was 4.25, BUN 50 along with an elevated ACE level. They called me and said I sarcoidosis. I really don't have any of the primary S/S of this autoimmune disease. I don't know where to go from here, they are referring me to another neurologist at a bigger hospital. I can't live my normal life, can't walk on my feet due extreme pain and I pass out at least 2x a week, which is not good for my old body. My BP upon laying and sitting runs like 117/72, upon standing it drops to like 70/50-50/30. I am on 0.1 mg of florinef, I tried increasing it but then my legs swelled up for a gain of 23#. I talked to Mayo Clinic today and all there specialists are booked out thru December. I have to be able to work, I can't stay home any longer than September 8th! Please advise me!
- Prednisone mixed results-it lets me breath (1 response)
have been on prednisone now for 3 years straight. Am taking 30mg a day just to breath. every time i have tried to taper off i have ended up in the emergency room unable to breath. That has been 7 times in the last year. I am 49 years old and was in good health 3-4 years ago. got a cough and it has been down hill.Prednisone worked great at first but then it starts to destroy the body.Had nasal passage surgery(waste of time)have broken many ribs from coughing.painful.when you are on prednisone your body takes 3-5 times longer to heal.craked tailbone from a slip. have seen over 12 doctors.reasonable gueswork. My best doc which is mine says do you want to suffocate to death or let your body try and fix itself if it can. im not for suffocation at all. Just a good medicine to counter the angriness of the steroid. Any ideas i am all ears. oh ya my eyes are starting to go and my joints as well
More reviews for: Ambien, Irritability
Comments from related studies:
From this study (1 year ago):
I was on 5mg and never had symptoms. I have a past history of grand mal but have been med free for over 18 yrs, but had a few orris. This past month my doctor up the dose to 10mg and I did not understand why or what was going on, I did not associate the two. But a friend witnessed a seizure three nights ago. I remember nothing at all. I have pancreatic pain and joint RA and OA. I get so painful from not moving every hour I am up walking and awake. I did without the ambien twice in 5 months for 15 days. I can just stop, and I tried Benadryl it dries me out. I AM GOING TO A NEUROLOGIST but I have a feeling predisposition is a factor on 10 mg. what do you think?
From this study (3 years ago):
George P on May, 7, 2012:
I developed torticollis soon after starting abilify. At the same time, I developed pain in my left side. An MRI revealed 4 ruptured disks in my spine, a known cause of torticollis.
Conclusion: I have no idea (neither, it seems, do the doctors). But I found abilify very effective for its purpose.
Tim J on Jul, 10, 2011:
I took this drug and it killed 40 percent of my achilles tendon.
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