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Review: could Amitriptyline cause Dementia?

We study 5,653 people who have side effects while taking Amitriptyline from FDA and social media. Among them, 8 have Dementia. Find out below who they are, when they have Dementia and more.

Stay connected: join a mobile support group for people who take Amitriptyline hydrochloride and have Dementia >>>

Amitriptyline hydrochloride

Amitriptyline hydrochloride (latest outcomes from 7,064 users) has active ingredients of amitriptyline hydrochloride. It is often used in migraine.

Dementia

Dementia (madness) (latest reports from 44,568 patients) has been reported by people with osteoporosis, depression, multiple sclerosis, high blood cholesterol, pain.

On Jul, 14, 2014: 5,639 people reported to have side effects when taking Amitriptyline hydrochloride. Among them, 11 people (0.20%) have Dementia. They amount to 0.02% of all the 44,334 people who have Dementia on eHealthMe.

Trend of Dementia in Amitriptyline hydrochloride reports

Time on Amitriptyline hydrochloride when people have Dementia * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Dementia0.00%0.00%0.00%0.00%0.00%100.00%0.00%

Gender of people who have Dementia when taking Amitriptyline hydrochloride * :

FemaleMale
Dementia81.82%18.18%

Age of people who have Dementia when taking Amitriptyline hydrochloride * :

0-12-910-1920-2930-3940-4950-5960+
Dementia0.00%0.00%0.00%0.00%0.00%27.27%0.00%72.73%

Severity of Dementia when taking Amitriptyline hydrochloride ** :

leastmoderateseveremost severe
Dementia0.00%0.00%100.00%0.00%

How people recovered from Dementia ** :

n/a

Top conditions involved for these people * :

  1. Blood cholesterol increased (4 people, 36.36%)
  2. Osteoporosis (3 people, 27.27%)
  3. Hypertension (3 people, 27.27%)
  4. Multiple myeloma (1 people, 9.09%)
  5. Insomnia (1 people, 9.09%)

Top co-used drugs for these people * :

  1. Neurontin (7 people, 63.64%)
  2. Fosamax (5 people, 45.45%)
  3. [therapy unspecified] (4 people, 36.36%)
  4. Effexor (3 people, 27.27%)
  5. Fluoxetine (2 people, 18.18%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Amitriptyline hydrochloride and have Dementia
- group for people who take Amitriptyline hydrochloride
- group for people who have Dementia

Comments from related studies:

  • From this study (1 week ago):

  • Elavil, 25mg @ night stopped an 11 month chronic headache after a head injury, I sustained 1 1/2 years ago.
    Additionally, Neurologist prescribed 100 mg Lyrica for chronic back/nerve pain from moderate/severe spinal injuries, sustained 20+ years earlier. (Crushed/cracked verabrae and 3 intervertebral disc bulges)
    I had been using Ibuprofen daily in moderate to heavy dosage for the last 20+ years. (800+ mg daily B/4 and then continually after recent head injury)
    I was advised to stop/reduce use of Motrin to 1/2 month or less. It is still the best pain relief but have reduced to PRN, perhaps 200 mg alternate days.
    Since treatment with Lyrica I've noticed reduced nerve pain and stopped using Elavil for sake of not feeling so "wrecked" in the mornings. I have also developed a severe sleep apnoea, treated unsuccessfully via CPAP device which is unbearable to use. I have subsequently suffered with depression/mood disorder for 20+ years and am currently un-treated for this long-standing vulnerability which came back with a vengence after the head-injury. I feel irregularity to my heart beat by the end of the day. I feel suicidal and violently angry.

    Reply

  • From this study (2 weeks ago):

  • from beginning Coumadin, patient has had problems "thinking". Holds head in hands and says " I can't think.

    Reply

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On eHealthMe, Amitriptyline Hydrochloride (amitriptyline hydrochloride) is often used for migraine. Find out below the conditions Amitriptyline Hydrochloride is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Amitriptyline Hydrochloride used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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