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Review: could Amitriptyline cause Mood swings?

Summary: Mood swings could be caused by Amitriptyline, especially for people who are female, 40-49 old, have been taking the drug for 6 - 12 months, also take Neurontin, and have Depression.

We study 5,588 people who have side effects while taking Amitriptyline from FDA and social media. Among them, 41 have Mood swings. Find out below who they are, when they have Mood swings and more.

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Amitriptyline hydrochloride

Amitriptyline hydrochloride (latest outcomes from 6,988 users) has active ingredients of amitriptyline hydrochloride. It is often used in migraine.

Mood swings

Mood swings (an extreme or rapid change in mood) (latest reports from 119,659 patients) has been reported by people with quit smoking, depression, birth control, attention deficit hyperactivity disorder, pain.

On Apr, 11, 2014: 5,464 people reported to have side effects when taking Amitriptyline hydrochloride. Among them, 41 people (0.75%) have Mood Swings. They amount to 0.03% of all the 119,401 people who have Mood Swings on eHealthMe.

Trend of Mood swings in Amitriptyline hydrochloride reports

Time on Amitriptyline hydrochloride when people have Mood swings * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Mood swings0.00%0.00%42.86%0.00%42.86%14.29%0.00%

Gender of people who have Mood swings when taking Amitriptyline hydrochloride * :

FemaleMale
Mood swings68.29%31.71%

Age of people who have Mood swings when taking Amitriptyline hydrochloride * :

0-12-910-1920-2930-3940-4950-5960+
Mood swings0.00%0.00%8.57%2.86%28.57%34.29%20.00%5.71%

Severity of Mood swings when taking Amitriptyline hydrochloride ** :

leastmoderateseveremost severe
Mood swings14.29%14.29%42.86%28.57%

How people recovered from Mood swings ** :

while on the drugafter off the drugnot yet
Mood swings0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Depression (10 people, 24.39%)
  2. Ill-defined disorder (7 people, 17.07%)
  3. Insomnia (6 people, 14.63%)
  4. Back pain (6 people, 14.63%)
  5. Attention deficit/hyperactivity disorder (5 people, 12.20%)

Top co-used drugs for these people * :

  1. Neurontin (13 people, 31.71%)
  2. Citalopram hydrobromide (7 people, 17.07%)
  3. Fentanyl (7 people, 17.07%)
  4. Sertraline hcl (6 people, 14.63%)
  5. Benadryl (6 people, 14.63%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Amitriptyline hydrochloride, Mood swings

You can also:

On eHealthMe, Amitriptyline Hydrochloride (amitriptyline hydrochloride) is often used for migraine. Find out below the conditions Amitriptyline Hydrochloride is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Amitriptyline Hydrochloride used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (2 years ago):

  • Medications improved fibromyalgia for about 1.5 years until side effects began to outweigh benefits. Tremor & myoclonic jerking seemed linked to build up of SINGULAIR, Cymbalta, SAVELLA, Elavil & Lyrica. Tremor, jerking and mood problems lessened when SINGULAIR was discontinued. Cognition improved slightly when Elavil was discontinued. Urinary retention lessened when Cymbalta dose was lowered to 40mg.

    Reply

  • From this study (4 years ago):

  • Very susceptible to extreme mood swings and very intolerent of other people. Loss of verbal reasoning and context and very sensitive to the wrong word said out of place.

    Reply

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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Related study

- Amitriptyline Hydrochloride side effects

 

Related symptom

- Mood Swings

 

 

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