Review: could Amlodipine besylate cause Fluid retention?
Summary: Fluid retention is found among people who take Amlodipine besylate, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Lasix, and have High blood pressure.
We study 17,555 people who have side effects while taking Amlodipine besylate from FDA and social media. Among them, 73 have Fluid retention. Find out below who they are, when they have Fluid retention and more.
You are not alone: join a mobile support group for people who take Amlodipine besylate and have Fluid retention >>>
Amlodipine besylate has active ingredients of amlodipine besylate. It is often used in high blood pressure. (latest outcomes from 19,098 Amlodipine besylate users)
Fluid retention (an abnormal accumulation of fluid in the blood) has been reported by people with primary pulmonary hypertension, high blood pressure, diabetes, type 2 diabetes, osteoporosis. (latest reports from 18,429 Fluid retention patients)
On Feb, 24, 2015: 17,555 people reported to have side effects when taking Amlodipine besylate. Among them, 73 people (0.42%) have Fluid Retention.
Time on Amlodipine besylate when people have Fluid retention * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Fluid retention||33.33%||58.33%||0.00%||0.00%||0.00%||8.33%||0.00% |
Gender of people who have Fluid retention when taking Amlodipine besylate * :
|Fluid retention||54.43%||45.57% |
Age of people who have Fluid retention when taking Amlodipine besylate * :
|Fluid retention||0.00%||0.00%||7.94%||0.00%||1.59%||7.94%||12.70%||69.84% |
Severity of Fluid retention when taking Amlodipine besylate ** :
|least||moderate||severe||most severe |
|Fluid retention||33.33%||50.00%||0.00%||16.67% |
How people recovered from Fluid retention ** :
|while on the drug||after off the drug||not yet |
|Fluid retention||0.00%||0.00%||100.00% |
Top conditions involved for these people * :
- Hypertension (17 people, 23.29%)
- Diabetes mellitus (10 people, 13.70%)
- Chronic myeloid leukaemia (8 people, 10.96%)
- Angina pectoris (7 people, 9.59%)
- Polyuria (5 people, 6.85%)
Top co-used drugs for these people * :
- Lasix (22 people, 30.14%)
- Aspirin (16 people, 21.92%)
- Furosemide (14 people, 19.18%)
- Allopurinol (12 people, 16.44%)
- Potassium chloride (11 people, 15.07%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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- I have been on amlodipine for approximately 3 months and have had terrible swelling in my legs and ankles along with pain and itching. should i be taken off this medication?
I was previously taking Propranolol for blood pressure which didn't bother me at all, but last year I developed a breathing problem and was given Symbicort to help get rid of wheezing. The Symbicort and Propranolol don't mesh well so I was then put on Amlodipine. The swelling, pain and itching occurred right away. I asked the pharmacist about it and also my doctor and they both said a small percentage of people have this problem on this medication. I have tried many times to get my doctor to take me off of this medication but he insists it is best for me, but I disagree. I really don't want to have this problem for the rest of my life and I also won't have any skin left on my legs from the scratching, not to mention the pain that accompanies the swelling which seem to creep up to my knees and thighs and sometimes is so painful I just go to bed to lay down and hopefully the hydroclorithiazide will remove some of this water so that pain will go away. The doctor also doubled my dose of Losartin and Hydroclorithiazide. I'm up about 4-6 times a night going to the bathroom so it also interrupts my sleep. Is anyone else having this problem. I would prefer to go back on the Propranolol and get something other than Symbicort that won't interact with each other. Then I won't have pain and itching all the time. Does anyone have any input on this. I would really appreciate it.
Thanks. Debbie CB
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Comments from related studies:
From this study (5 years ago):
My mother has had a lot of improvement compared to how she was in and out of the hospital about every 3 months for congestive heart failure. She looks well now, but has been having memory problems and strange behavior again since her Lasix was increased from 10mg twice a day to 20mg twice a day for about 2 weeks now. She was improving with her combination of Phosphatidylserine 100 Plus (helps improve cognitive functions that decline with age),5mg Aricept (for Dementia Alzh. Type), 10mg Namenda (for Dementia Alzh. Type), Vitamin B Complex and 2000mg of Omega 3 Fish Oil. Because of her weight going up and down & some swelling of her feet, her Lasix was increased. In the past her dosage of Lasix was much higher especially while in the hospital. Make me wonder if large dosages of Furosemide eventually contributes to Alzheimer's.
NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.
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