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Review: could Amoxicillin cause Crohn's disease?

Summary: Crohn's disease could be caused by Amoxicillin, especially for people who are female, 10-19 old, have been taking the drug for 1 - 6 months, also take Accutane, and have Acne.

We study 22,155 people who have side effects while taking Amoxicillin from FDA and social media. Among them, 163 have Crohn's disease. Find out below who they are, when they have Crohn's disease and more.

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Amoxicillin

Amoxicillin (latest outcomes from 24,064 users) has active ingredients of amoxicillin. It is often used in infection.

Crohn's disease

Crohn's disease (condition that causes inflammation of the gastrointestinal tract) (latest reports from 156,443 patients) has been reported by people with acne, pain, inflammatory bowel disease, depression, high blood pressure.

On Apr, 8, 2014: 22,008 people reported to have side effects when taking Amoxicillin. Among them, 169 people (0.77%) have Crohn's Disease. They amount to 0.11% of all the 156,315 people who have Crohn's Disease on eHealthMe.

Trend of Crohn's disease in Amoxicillin reports

Time on Amoxicillin when people have Crohn's disease * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Crohn's disease33.33%46.15%0.00%0.00%0.00%0.00%20.51%

Gender of people who have Crohn's disease when taking Amoxicillin * :

FemaleMale
Crohn's disease59.80%40.20%

Age of people who have Crohn's disease when taking Amoxicillin * :

0-12-910-1920-2930-3940-4950-5960+
Crohn's disease0.00%0.60%45.24%16.67%7.74%7.74%17.26%4.76%

Severity of Crohn's disease when taking Amoxicillin ** :

leastmoderateseveremost severe
Crohn's disease0.00%100.00%0.00%0.00%

How people recovered from Crohn's disease ** :

n/a

Top conditions involved for these people * :

  1. Acne (79 people, 46.75%)
  2. Crohn's disease (29 people, 17.16%)
  3. Rhinitis (21 people, 12.43%)
  4. Headache (21 people, 12.43%)
  5. Skin infection (18 people, 10.65%)

Top co-used drugs for these people * :

  1. Accutane (131 people, 77.51%)
  2. Asacol (56 people, 33.14%)
  3. Prednisone (32 people, 18.93%)
  4. Claritin (27 people, 15.98%)
  5. Imuran (25 people, 14.79%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

Comments for this study:

Cynthia (1 year ago):

My 8-month-old has an ear infection and the dr mentioned this study and recommended that I have the baby ride it out. Any thoughts on this? Basically not giving my baby the antibiotic? Any studies on babies using amox and later getting chrons?
Reply the comment

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Amoxicillin, Crohn's disease

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On eHealthMe, Amoxicillin (amoxicillin) is often used for infection. Find out below the conditions Amoxicillin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Amoxicillin used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (2 days ago):

  • When started using omeprazole last March 3 ,2014 ,blisters started to show up but i continue taking up omeprazole 40mg and amoxicillin 500mg until now.My psoriasis arthritis worsened.

    Reply

  • From this study (4 days ago):

  • Swelling of eyes, lips, tongue and throat. Angioedemas on fingers, neck, ear, abdomen, arms and buttocks.

    Reply

  • From this study (1 week ago):

  • I have had a red rash sometimes itchy on my neck. when it first started it looked like someone took a rope and my neck. after a few week the red is still there (my skin is with this is dry) Thought at first it was stress. I stopped the medication about a week ago, but my neck is still red

    Reply

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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