Review: could Amoxicillin cause Irritability?
Summary: Irritability is found among people who take Amoxicillin, especially for people who are male, 30-39 old, have been taking the drug for < 1 month, also take medication Fluconazole, and have Depression.
We study 22,270 people who have side effects while taking Amoxicillin from FDA and social media. Among them, 135 have Irritability. Find out below who they are, when they have Irritability and more.
You are not alone: join a mobile support group for people who take Amoxicillin and have Irritability >>>
Amoxicillin has active ingredients of amoxicillin. It is often used in infection. (latest outcomes from 24,185 Amoxicillin users)
Irritability has been reported by people with depression, quit smoking, pain, stress and anxiety, attention deficit hyperactivity disorder. (latest reports from 23,559 Irritability patients)
On Feb, 27, 2015: 22,270 people reported to have side effects when taking Amoxicillin. Among them, 135 people (0.61%) have Irritability.
Time on Amoxicillin when people have Irritability * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
Gender of people who have Irritability when taking Amoxicillin * :
Age of people who have Irritability when taking Amoxicillin * :
Severity of Irritability when taking Amoxicillin ** :
|least||moderate||severe||most severe |
How people recovered from Irritability ** :
Top conditions involved for these people * :
- Depression (32 people, 23.70%)
- Pain (25 people, 18.52%)
- Multiple myeloma (20 people, 14.81%)
- Neoplasm malignant (14 people, 10.37%)
- Pain in jaw (9 people, 6.67%)
Top co-used drugs for these people * :
- Fluconazole (35 people, 25.93%)
- Paxil (29 people, 21.48%)
- Lorazepam (28 people, 20.74%)
- Oxycontin (27 people, 20.00%)
- Cipro (26 people, 19.26%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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- Drug interractions savella. amoxicillin
Sudden ache, pain and neuropathy in right hand and wrist within 8 hours of sterting Amoxicillin.
- Yaz was the cause of increasing my pmdd, pms, irritability and depression symptoms
I had taken Ortho Novum 777 from the age of 18 to 28 stopping in-between pregnancies. I had 3 children between the ages of 21 and 29.
In my early 30's I decided to stop taking birth control pills simply because I 'thought' it would be a healthier thing to do for my body. I did know that unless I was taking Ortho Novum that my period were not the standard 28 day routine. They were irregular and would be anywhere from 28 to 38 days. The longer the time in between periods the worse the pms symptoms would be. My theory is most likely because of the extended time between when I perceived a period and when I actually got it. It could very well have been psychosomatic but when my period would finally arrive, irritability and bloating would subside within a day or two. It was like a reset button and relief. I was calmer, more rational, even Kiel and motivated.
In addition to the irregular pattern of my periods when off if birth control pills I also experienced pms twice a month. It would happen mid month when I was ovulating. The ovulation would be uncomfortable, I'd feel bloated again, and the cramps were painful. I'd move from ovulation week of irritability to PMS week of even greater irritability. I'd be waiting and counting down til my period was suppose to happen in anticipation of relief.
I remember age 32 being significant for some reason. Upon reflecting back over the years while seeking treatment for a solution out of the psyco cycle I remember referring to age 32 as the year that things were never the same as they were in my 20's.
Mid 30's I had asked my ob/gyn if I could go back on the Ortho Novum 777. I was told that I was too old. This was early 2000's, 2003 or 2004. I was given a different birth control pill that he recommended and I tried that for a while but it wasn't making things better and I don't remember the exact details. I tried bio identical hormones... That wasn't really helpful either, it was more work and a long process that I stuck with for at least a year trying to get the formula right. I finally threw the towel in on that.
Then a different ob/gyn suggested I try progesterone only. He prescribed a pink round ball of a pill. I was to take it the last 10 days of the month. I tried that for 3 or 4 months, it wasn't making things better... in fact I think it made it worse. Then I went cold turkey again for the better part of a year. At age 37, after not finding a doctor that was helping the situation I decided to find a doctor in AZ. I live full time in CA but had a vacation home in AZ so I thought I'd try that for a change.
I did find a doctor and she prescribed yaz 24 day. She said it should help me as it has helped many other women. I took the yaz for a little better than a year and psychologically I thought I had a winner! This doctor sounded like she knew my problems and that this was the solution. Alas it was not. I remember feeling the most depressed is ever felt. I didn't think it had anything to do with the yaz, I figured it was just life. When I returned to that doctor after a year I explained my situation. She then recommended that I get an ablation!?! I was never a heavy bleeder and it makes no sense to have that done, but she sold me on the idea that it would help my problem. I realize now she was doing exactly that, selling. I'm sure it was a nice payment from the insurance company.
None of my issues were solved. I had stopped taking the yaz or any birth control at that point. My period were non existent after boiling my uterus in boiling water, which is what the ablation is. And to this day my period is hardly worth talking about or being prepared for. It's spotting for a couple 3 days at best. With regard to my symptoms, the pms, pmdd, extreme irritability, depression all that stayed the same. I tried Seasonal for about 2 months and that was not good, it seemed to 'amp' the 'hot' - not physically hot but an irritable term I use to describe the upped level my nerves set at.
I did exercise pretty regularly during all if this. The times I wasn't exercising were over the top as far as pmdd symptoms so that motivates you to get your rear to the gym. On the Yaz 24 day I knew something wasn't right. At day 14 I'd feel the symptoms if ovulation, not imagined but real. I was slightly irritable and had cramps for 2 to 3 days. At day 17, a Wednesday the irritability would ramp up and the depression would start to be present for the next 2 weeks.
The following Wednesday was day 24, that was the last day of taking the pill. I did get a bit of relief after stopping the pill and 4 days later I resumed taking the next months pack on Sunday. The thing is I wouldn't get my period until Tuesday after I started the new pack? I know that my period should have happened between day 24 and 28 but it never did. It always started on day 31 or 32 and lasted 2 to 3 days. Then the whole cycle begins again with day 14.
On Yaz 24
Day 1 Sunday
Day 3 or 4 Tuesday and my period would start.
Day 5 or 6 my period ended
Day 14 - Day 17 ovulation type cramping
Day 17 irritability started ramping up into PMS, PMDD & Depression
Symptoms were worse without exercise by at least 40%
Day 24 Wednesday, last day of Yaz pack for the month
Day 25 slight mood improvement
Day 30-31 (same as Day 3/4above) period would start
The ob/gyn expertise wasn't working, male or female. I went to my regular general practitioner for a check up and had done much research on the type of hormones in the Yaz, Yasmin and many others. I was convinced that I need to move over to Yasmin 21 day. It had a but more estrogen and it was only 21 instead of 24 days so worth a try.
She asked me when the last time I felt 'normal' with regard to the hormones. I told her that as far as I can recall it was when I was in my 20's when I was taking the Ortho Novum 777. She said why don't we have you start taking that again! I was like, what? I explained I was told I could not take that because of my age and I thought some doctor had told me it had been discontinued years ago anyway. She said no, I can prescribe it to you, it's still available. I was a little excited about that. Maybe... just maybe that would be a solution for relief. My blood pressure is 100/70 always has been low, I don't smoke and I'm 5' 8", 150 pounds. She saw no reason for me not to try it again. We agreed that I would and if it didn't go well we'd try the Yasmin.
I've been in the Ortho Novum, my package and brand saying Alyacen 7/7/7 for 3 weeks now. Today is Sunday and I stop taking active pills for 7 days now. At day 7 or so I noticed how much easier it was becoming to get out of bed in the morning. I began noticing I had an interest in getting something done. I didn't have a big heavy cloud urging me to just stay in bed. I started feeling alive again.
The jury is still out and I have ordered a second months supply but I am deeply encouraged. During week 3 I have been crampier than on the yaz but in a very normal feeling way. Like my body is preparing for menstruation. I'm anticipating bleeding heavier than I'm used to, but in a good way. The cramping has been something I definitely notice much much more so but it's manageable. What I also notice is lack...... huge overwhelming lack of that horrible irritability. I'm more sensitive than weeks one and two but it's nothing by comparison. I've been more level headed, more 'normal'. Time will tell if this is my cure for the next 6 or so years but I'm extremely encouraged right now. I literally feel the best I have in years and there is some pretty crapy stressful things going on in my life. But I can handle them-
Side note, I am a Type A personality. I am under a lot of stress running my own business often. I am a mother of 3 and a very capable woman. Watch out world if I'm back like my 20's nothing will stop me. I'm positive, excited and thankful for this moment.
It stinks if this is this truly is the solution to my problem, as years of my life and those around me have been effected. But it does no good to look back I'm looking forward with great anticipation!
Good Luck, I hope this monologue can help someone else just like me and I'll be saving a copy for future female generations of mine.
- Lupus induced by amoxicillin (1 response)
Was given Amoxicillin for Strep Throat and on day 10 I noticed a rash starting on my torso and began to feel ill, as if I had the flu. Went to emerg and got sent home with Benadryl. Woke up the next morning to the rash getting worse and an overall feeling of fatigue. Went to emerg again and this time had blood taken and the results showed an extreme rise in my white blood cells and by then, I had a fever. I was airlifted to another hospital where they did tests, but really had no idea what was wrong. I discharged myself with a script for corticosteroids and by then my joints began to stiffen, to a point of barely being able to walk and the pain was excruciating! I had to be cared for by my husband and struggled to lift my tea cup, or get out of bed. This lasted for about a month and then gradually began to subside. The doctors never did have answers for any of it. They chalked it up to an allergy to Amoxicillin. One mentioned "Steven Johnson Syndrome".
- Amoxycillin and ear popping.
I'm 30. I have otitis externa, but have never suffered with ear popping as a symptom. I had a flare up 2 wks before being prescribed this drug. I took a spay abx treatment which caused severe pain in my ears, so stopped taking that 5 days into the 7 day course. 4-5 days into my amoxicillin treatment for a uti, and my ears are popping. I have no known other medical problems, and am on no other meds.
- Etanercept and irritability
I have been on Etanercept for 8 years for Psoriasis. Previous to this I was on
Methotrexate, Cyclosporine, Retinodes and ACTH injections.Since being on 25mg twice a week I have been 98% clear.The only side effect to date is "Irritability" which lasts about 24hrs.
This Drug has been my saving grace.
More reviews for: Amoxicillin, Irritability
Comments from related studies:
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George P on May, 7, 2012:
I developed torticollis soon after starting abilify. At the same time, I developed pain in my left side. An MRI revealed 4 ruptured disks in my spine, a known cause of torticollis.
Conclusion: I have no idea (neither, it seems, do the doctors). But I found abilify very effective for its purpose.
Tim J on Jul, 10, 2011:
I took this drug and it killed 40 percent of my achilles tendon.
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