Review: could Amphotericin b cause Neutrophil count decreased?
Summary: Neutrophil count decreased is found among people who take Amphotericin b, especially for people who are male, 40-49 old, have been taking the drug for 1 - 6 months, also take medication Meropenem, and have Acute lymphocytic leukaemia.
We study 4,957 people who have side effects while taking Amphotericin b from FDA and social media. Among them, 33 have Neutrophil count decreased. Find out below who they are, when they have Neutrophil count decreased and more.
You are not alone: join a mobile support group for people who take Amphotericin b and have Neutrophil count decreased >>>
Amphotericin b has active ingredients of amphotericin b. It is often used in thrush. (latest outcomes from 4,969 Amphotericin b users)
Neutrophil count decreased
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell) has been reported by people with schizophrenia, hepatitis c, multiple myeloma, high blood pressure, breast cancer. (latest reports from 12,242 Neutrophil count decreased patients)
On Jan, 28, 2015: 4,957 people reported to have side effects when taking Amphotericin b. Among them, 33 people (0.67%) have Neutrophil Count Decreased.
Time on Amphotericin b when people have Neutrophil count decreased * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Neutrophil count decreased||44.44%||55.56%||0.00%||0.00%||0.00%||0.00%||0.00% |
Age of people who have Neutrophil count decreased when taking Amphotericin b * :
|Neutrophil count decreased||0.00%||3.03%||3.03%||24.24%||15.15%||24.24%||9.09%||21.21% |
Top conditions involved for these people * :
- Acute lymphocytic leukaemia (6 people, 18.18%)
- Prophylaxis (4 people, 12.12%)
- Gastric ulcer (4 people, 12.12%)
- Pseudomembranous colitis (4 people, 12.12%)
- B-cell lymphoma (3 people, 9.09%)
Top co-used drugs for these people * :
- Meropenem (10 people, 30.30%)
- Sulfamethoxazole and trimethoprim (6 people, 18.18%)
- Sprycel (6 people, 18.18%)
- Polyethylene glycol (6 people, 18.18%)
- Vancomycin (6 people, 18.18%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you have Neutrophil Count Decreased while taking Amphotericin B?
You are not alone! Join a mobile support group:
- support group for people who take Amphotericin b and have Neutrophil Count Decreased
- support group for people who take Amphotericin b
- support group for people who have Neutrophil Count Decreased
Drugs in real world that are associated with:
Could your condition cause:
Can you answer these questions (Ask a question):
- Can amphotericin make nexavar less effective?
Our son failed to achieve remission after the inducation and then subsequent consolidation phases of treatment for AML The second attempt failed as well. Since then he began to take Nexavar 200mg X 2 BID for the flt3 gene mutation and experienced dramatic results immediately. Blasts cells dropped to less than .1 from 40% and white blood cells from over 50 to .3. At the same time that he began this drug though he also began to take Amphotericin for a fungal infection in his lungs. At present, two weeks later, we are starting to see a gradual increase in his wbc level as well as the blast cells (.2 to .6 levels) again. Hence the question over whether the Amphotericin is affecting the effectiveness of the Nexavar.
More questions for: Amphotericin b, Neutrophil count decreased
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Comments from related studies:
From this study (6 months ago):
Fever over 102, chills, horrible pain began on day 5 taking medication. Red blotchy rash began appearing late following day on chest and back and gradually spread. Blood blister-type rash on legs. Went to ER after 4 days. Told I have sulfa allergy. Given iV fluid and meds. Need follow up blood tests to recheck my low WBC, platelets and Neu. Counts. Prescribed Benadryl.
From this study (3 years ago):
Nasty drug. While indicated not sure of its effectiveness for my condition.......they have not been able to precisely determine the type of mucor invading my body. The problem I have is that the side effects can be somewhat alleviated by premeditation and use of an opioid prn for rigors/pain (protocols call for Demerol but it makes me sick, Fentanyl has been used instead) not all doctors writing the orders for this drug's administration understand these medication protocols and I suffer needlessly.
From this study (3 years ago):
Despite severe reaction to medication (required treatment with adenosine for tachycardia and piriton for all over body hives/urticaria with itching) the treatment was not stopped for 5 days. Very unpleasant for child concerned and nurses carrying out care but medic insisted drug continued for full 5 days. Please more widely disseminate information about these side-effects.
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