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Review: could Amphotericin b cause Neutrophil count decreased?

Summary: Neutrophil count decreased could be caused by Amphotericin b, especially for people who are male, 40-49 old, have been taking the drug for 1 - 6 months, also take Meropenem, and have Acute lymphocytic leukaemia.

We study 4,956 people who have side effects while taking Amphotericin b from FDA and social media. Among them, 33 have Neutrophil count decreased. Find out below who they are, when they have Neutrophil count decreased and more.

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On Apr, 16, 2014: 4,956 people reported to have side effects when taking Amphotericin b. Among them, 33 people (0.67%) have Neutrophil Count Decreased. They amount to 0.05% of all the 60,155 people who have Neutrophil Count Decreased on eHealthMe.

Trend of Neutrophil count decreased in Amphotericin b reports

Time on Amphotericin b when people have Neutrophil count decreased * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Neutrophil count decreased44.44%55.56%0.00%0.00%0.00%0.00%0.00%

Age of people who have Neutrophil count decreased when taking Amphotericin b * :

0-12-910-1920-2930-3940-4950-5960+
Neutrophil count decreased0.00%3.03%3.03%24.24%15.15%24.24%9.09%21.21%

Top conditions involved for these people * :

  1. Acute lymphocytic leukaemia (6 people, 18.18%)
  2. Prophylaxis (4 people, 12.12%)
  3. Gastric ulcer (4 people, 12.12%)
  4. Pseudomembranous colitis (4 people, 12.12%)
  5. B-cell lymphoma (3 people, 9.09%)

Top co-used drugs for these people * :

  1. Meropenem (10 people, 30.30%)
  2. Maxipime (6 people, 18.18%)
  3. Sprycel (6 people, 18.18%)
  4. Etoposide (6 people, 18.18%)
  5. Sulfamethoxazole and trimethoprim (6 people, 18.18%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

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