Arava and Diarrhea - from FDA reports


Summary

Diarrhea is found among people who take Arava, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Methotrexate, and have Rheumatoid arthritis . We study 22,860 people who have side effects while taking Arava from FDA. Among them, 1,059 have Diarrhea. Find out below who they are, when they have Diarrhea and more.

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Arava

Arava has active ingredients of leflunomide. It is often used in rheumatoid arthritis. (latest outcomes from Arava 23,131 users)

Diarrhea

Diarrhea has been reported by people with high blood pressure, multiple sclerosis, rheumatoid arthritis, crohn's disease, pain (latest reports from 264,661 Diarrhea patients).

On Jan, 21, 2017

22,860 people reported to have side effects when taking Arava.
Among them, 1,059 people (4.63%) have Diarrhea


Number of reports submitted per year:

Could Arava cause Diarrhea?

Time on Arava when people have Diarrhea *:

  • < 1 month: 24.73 %
  • 1 - 6 months: 46.77 %
  • 6 - 12 months: 5.91 %
  • 1 - 2 years: 11.56 %
  • 2 - 5 years: 7.26 %
  • 5 - 10 years: 2.69 %
  • 10+ years: 1.08 %

Gender of people who have Diarrhea when taking Arava *:

  • female: 80.13 %
  • male: 19.87 %

Age of people who have Diarrhea when taking Arava *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.24 %
  • 20-29: 2.01 %
  • 30-39: 5.57 %
  • 40-49: 13.74 %
  • 50-59: 26.9 %
  • 60+: 51.54 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (799 people, 75.45%)
  • High Blood Pressure (83 people, 7.84%)
  • Pain (66 people, 6.23%)
  • Osteoporosis (53 people, 5.00%)
  • Psoriatic Arthropathy (48 people, 4.53%)

Top co-used drugs for these people *:

  • Methotrexate (231 people, 21.81%)
  • Enbrel (177 people, 16.71%)
  • Prednisone (155 people, 14.64%)
  • Humira (131 people, 12.37%)
  • Plaquenil (109 people, 10.29%)

Top other side effects for these people *:

  • Nausea (224 people, 21.15%)
  • Nausea And Vomiting (213 people, 20.11%)
  • Fever (172 people, 16.24%)
  • Weakness (149 people, 14.07%)
  • Weight Decreased (145 people, 13.69%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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