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Review: could Aricept cause Mania?

Summary: Mania could be caused by Aricept, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take Seroquel, and have Dementia alzheimer's type.

We study 14,892 people who have side effects while taking Aricept from FDA and social media. Among them, 40 have Mania. Find out below who they are, when they have Mania and more.

On Apr, 11, 2014: 14,806 people reported to have side effects when taking Aricept. Among them, 40 people (0.27%) have Mania. They amount to 0.08% of all the 52,033 people who have Mania on eHealthMe.

Trend of Mania in Aricept reports

Time on Aricept when people have Mania * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Mania55.00%20.00%15.00%10.00%0.00%0.00%0.00%

Gender of people who have Mania when taking Aricept * :

FemaleMale
Mania54.00%46.00%

Age of people who have Mania when taking Aricept * :

0-12-910-1920-2930-3940-4950-5960+
Mania0.00%0.00%0.00%0.00%0.00%4.76%21.43%73.81%

Severity of Mania when taking Aricept ** :

n/a

How people recovered from Mania ** :

n/a

Top conditions involved for these people * :

  1. Dementia alzheimer's type (13 people, 32.50%)
  2. Depression (6 people, 15.00%)
  3. Cognitive disorder (6 people, 15.00%)
  4. Bipolar disorder (3 people, 7.50%)
  5. Dementia (2 people, 5.00%)

Top co-used drugs for these people * :

  1. Seroquel (12 people, 30.00%)
  2. Amoban (8 people, 20.00%)
  3. Gramalil (8 people, 20.00%)
  4. Haldol (4 people, 10.00%)
  5. Zoloft (4 people, 10.00%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Aricept, Mania

You can also:

On eHealthMe, Aricept (donepezil hydrochloride) is often used for alzheimer's disease. Find out below the conditions Aricept is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Aricept used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (1 week ago):

  • Became irritable and high strung a couple of weeks after Mirena was placed. I did not notice this side effect, but others around me noticed it, after 2-3 months started going into a manic phase for several weeks followed by depression. Told gynecologist, she removed it and I began feeling myself again after a couple of weeks. I have a family history of bipolar, but no personal history of any mental/emotional problems. A rare side effect, but my system cannot handle synthetic hormones. Now have a copper IUD in place without any side effects. Glad I had a supportive gynecologist, she told me it normally causes depression in sensitive people, but when we really researched it, we found there are cases of other mental emotional side effects in sensitive people.

    Reply

  • From this study (1 week ago):

  • I took Sertraline I am 110 pounds, the doctor started me out on 25 mg and kicked me up to 100 mg, I became manic badly and now I am off for one year and I feel they have messed up my mind, I can no longer concentrate or function properly, I am depressed and went to another doctor who just started me on Latuda, hopefully with better results.Can Sertraline do this damage to people???

    Reply

  • From this study (2 weeks ago):

  • Are these drugs compatible? Does the Azilect help with falling as well as tremors?

    Reply

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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