Review: could Aricept cause Mania?


Mania is found among people who take Aricept, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Seroquel, and have Dementia alzheimer's type . We study 15,742 people who have side effects while taking Aricept from FDA and social media. Among them, 43 have Mania. Find out below who they are, when they have Mania and more.

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Aricept has active ingredients of donepezil hydrochloride. It is often used in dementia alzheimer's type. (latest outcomes from Aricept 16,467 users)


Mania (a state of abnormally elevated or irritable mood) has been reported by people with drug ineffective, confusional state, drowsiness, insomnia, fatigue (latest reports from 11,830 Mania patients).

On Aug, 27, 2016

15,742 people reported to have side effects when taking Aricept.
Among them, 43 people (0.27%) have Mania

Number of reports submitted per year:

Could Aricept cause Mania?

Time on Aricept when people have Mania *:

  • < 1 month: 71.43 %
  • 1 - 6 months: 28.57 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Mania when taking Aricept *:

  • female: 51.16 %
  • male: 48.84 %

Age of people who have Mania when taking Aricept *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 5.56 %
  • 50-59: 19.44 %
  • 60+: 75.0 %

Top conditions involved for these people *:

  • Dementia Alzheimer's Type (8 people)
  • Depression (5 people)
  • Cognitive Disorder (4 people)
  • Dementia (3 people)
  • Bipolar Disorder (3 people)

Top co-used drugs for these people *:

  • Seroquel (6 people)
  • Zyprexa (4 people)
  • Zoloft (4 people)
  • Namenda (4 people)
  • Haldol (4 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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