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Review: could Azathioprine cause Constipation?





Summary: Constipation is found among people who take Azathioprine, especially for people who are female, 40-49 old, have been taking the drug for 1 - 2 years, also take medication Humira, and have Crohn's disease.

We study 14,240 people who have side effects while taking Azathioprine from FDA and social media. Among them, 102 have Constipation. Find out below who they are, when they have Constipation and more.

You are not alone: join a mobile support group for people who take Azathioprine and have Constipation >>>

Azathioprine

Azathioprine has active ingredients of azathioprine sodium. It is often used in crohn's disease. (latest outcomes from Azathioprine 14,431 users)

Constipation

Constipation has been reported by people with osteoporosis, pain, high blood pressure, depression, high blood cholesterol.(latest reports from Constipation 80,049 patients)

On Nov, 25, 2014: 14,237 people reported to have side effects when taking Azathioprine. Among them, 102 people (0.72%) have Constipation.

Trend of Constipation in Azathioprine reports

Time on Azathioprine when people have Constipation * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Constipation28.57%14.29%0.00%42.86%0.00%0.00%14.29%

Gender of people who have Constipation when taking Azathioprine * :

FemaleMale
Constipation60.38%39.62%

Age of people who have Constipation when taking Azathioprine * :

0-12-910-1920-2930-3940-4950-5960+
Constipation0.00%2.97%7.92%7.92%8.91%27.72%17.82%26.73%

Severity of Constipation when taking Azathioprine ** :

leastmoderateseveremost severe
Constipation0.00%100.00%0.00%0.00%

How people recovered from Constipation ** :

while on the drugafter off the drugnot yet
Constipation0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Crohn's disease (27 people, 26.47%)
  2. Hypertension (19 people, 18.63%)
  3. Pain (15 people, 14.71%)
  4. Prophylaxis (10 people, 9.80%)
  5. Sarcoidosis (8 people, 7.84%)

Top co-used drugs for these people * :

  1. Humira (20 people, 19.61%)
  2. Prednisone (20 people, 19.61%)
  3. Prednisolone (17 people, 16.67%)
  4. Cyclosporine (13 people, 12.75%)
  5. Cyclophosphamide (13 people, 12.75%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Constipation while taking Azathioprine?

You are not alone! Join a mobile support group:
- support group for people who take Azathioprine and have Constipation
- support group for people who take Azathioprine
- support group for people who have Constipation

Drugs in real world that are associated with:

Could your condition cause:

Can you answer these questions (Ask a question):

  • Cymbalta r/t autonomic neuropathy
    (Asked by a 62 year old man who has Stomach Pains, GERD, Fatique, Constipation, Dizzness, Early Satiety)
    neurotin
    losartan 20 mg
    tired all the time, dizziness, chronic constipation, stomach pains, pins and needles, diabetic type 2 hx alcoholism resolved, gerd, early satiety
  • Why would i get copd since i never smoked?
    (Asked by a 62 year old woman who has Rheumatoid Arthritis, PBC, AIH, Asthma, and takes Vitamin D, Calcium Carbonate, Anturol, Morphine Sulfate, Levothyroxine Sodium, Pyridium, Cyclobenzaprine Hydrochloride, Azathioprine, Proair Hfa, Advair Diskus 250/50, Combivent)
    I have several autoimmune disorders, I was shocked to get the COPD diagnosis since I have never smoked but I had second hand smoke first 23 years of my life.
    My doctor said my Autoimmune Hepatitis and Primary Biliary Cholingitis set me up for COPD.
  • Does zoloft cause ringing in the ears, like tinnitus? i've been on it for a month and noticed the ringing in the ears about a week ago, and it's just constant ringing and it's driving me insane. (1 answer)
    (Asked by a 24 year old man who has Ringing In The Ears, and takes Dicyclomine Hydrochloride, Benadryl, Tylenol, Lialda, Azathioprine, Prednisone, Ambien, Zoloft)
    I've been on most of the medications for more than a year and it hasn't been that bad getting used to them. But I've been on Zoloft and ambien for about a month now, and I've been noticing a lot of side effects. The one I just recently noticed and that has been driving me completely insane, is the ringing in the ears. It's been about a week now and I just don't know what to do anymore. If it is the Zoloft then I can finally just stop taking it and make this stop. If anyone has an answer or knows what to do, PLEASE help. I'm at my wits end.
  • Gastro with constipation in a 4 year old only cause pain at night?
    (Asked by a 4 year old boy who has Constipation, Gastroenteritis - Viral)
    In childrens hospital now have given the tag virus for stomach pain at night that is relieved by morphine
  • Can my symptoms actually pinpoint a cause/condition? (1 answer)
    (Asked by a 27 year old woman who has Vulvovaginal Dryness During Intercourse, Acne Cystic, Bilateral Stenosis, Irregularity Of Bowels, Muscle Tightness, Menstrual Periods - Heavy, Prolonged, Or Irregular, Menstruation - Painful, Painful Sexual Intercourse, Pelvic Discomfort, Chest Pain, Abdominal Bloating, Deep Knee Pain, Extreme Thigh Pain, Sometimes Bulging, Flattened/deflated & Bulging Discs, Chronic Pain, Hirsutism, and takes Soma, Norco)
    I would just like insight on this. I'm on pain management right now, but it's just to manage the pain. Every thing else has really been not taken serious by any physican it office I've been to. Is this normal stuff many woman go through? I'm just sick of feeling like this between the constant pain & the daily having to pluck hairs it's insane. I'm in fantastic shape(used to be double my weight & now I'm 100lbs), the best looking I've ever been with a incredibly good looking husband & a wonderful family. My issues seem to detour a lot of things & while I'm young I'd like to get this solved or some type of solution to even maintain myself, not looking for a miracle, but would really appreciate answers.

More questions for: Azathioprine, Constipation

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    (Posted by a 49 year old woman who has Constipation, Peripheral Neuropathy, Orthostatic Hypotension, Chronic Kidney Disease, and takes Milk Thistle, Zolpidem, Melatonin, Xanax, Adderall 30, Zorvolex)
    The orthostatic BP started in mid April, I was only dizzy upon wakening then it would subside. I have never been a big breakfast eater so I started doing that. We were in Disney later in April and I was extremely fatigued, to the point of not wanting to walk, Disney would be the first time I passed out when getting dizzy. I of course said I had gotten too warm and was exhausted from work the previous week. The dizziness continued in the mornings & I passed out several more times. On May 1st, I passed out while putting my make-up on and hit my eye on the faucet and head on the tile floor, despite that I went to work thinking it would subside, it didn't. I went to the ER directly after work. They ran a B-met on me and my GFR was 11 and creatinine 3.95. They admitted me to a larger hospital for evaluation. While in there, they pumped me with fluids continuously, saying I had severe dehydration. My kidney function improved, my creatinine levels went back down to 1.34. After 5 days I was discharged and told to see a cardiologist and endo. The endo doc cancelled my appointment on the basis it was not his area. I had had a cortisol and ACTH testing which I guess was normal. I saw the cardiologist, who said it wasn't cardio. I had had an echocardiogram in the hospital and EKG monitoring. Cardio sent me to neurology, the PNRN did a basic neurological exam and drew blood for disease markers such as Lupus, sjorgens, hepatitis, ect. All disease markers came back negative, but my GFR was at 11 again and creatinine was 4.25, BUN 50 along with an elevated ACE level. They called me and said I sarcoidosis. I really don't have any of the primary S/S of this autoimmune disease. I don't know where to go from here, they are referring me to another neurologist at a bigger hospital. I can't live my normal life, can't walk on my feet due extreme pain and I pass out at least 2x a week, which is not good for my old body. My BP upon laying and sitting runs like 117/72, upon standing it drops to like 70/50-50/30. I am on 0.1 mg of florinef, I tried increasing it but then my legs swelled up for a gain of 23#. I talked to Mayo Clinic today and all there specialists are booked out thru December. I have to be able to work, I can't stay home any longer than September 8th! Please advise me!
  • Caused by azathioprine (3 responses)
    (Posted by a 34 year old woman who has Crohn's Disease, and takes Azathioprine)
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    (Posted by a 29 year old woman who has Simple Partial Seizures, Lightheadedness - Fainting, Constipation, Nausea, Chills, and takes Celexa)
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