Review: could Azathioprine cause Drug Resistance?


Summary

Drug resistance is found among people who take Azathioprine, especially for people who are male, 20-29 old , have been taking the drug for 5 - 10 years, also take medication Prednisolone, and have Pemphigus . We study 19,879 people who have side effects while taking Azathioprine from FDA and social media. Among them, 43 have Drug resistance. Find out below who they are, when they have Drug resistance and more.

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Azathioprine

Azathioprine has active ingredients of azathioprine sodium. It is often used in crohn's disease. (latest outcomes from Azathioprine 20,848 users)

Drug Resistance

Drug resistance (reduction in effectiveness of a drug) has been reported by people with pleural effusion, back pain, drowsiness, diarrhea, high blood cholesterol (latest reports from 3,065 Drug resistance patients).

On Aug, 25, 2016

19,879 people reported to have side effects when taking Azathioprine.
Among them, 43 people (0.22%) have Drug Resistance


Number of reports submitted per year:

Could Azathioprine cause Drug resistance?

Time on Azathioprine when people have Drug Resistance *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 50 %
  • 5 - 10 years: 50 %
  • 10+ years: 0.0 %

Gender of people who have Drug Resistance when taking Azathioprine *:

  • female: 41.46 %
  • male: 58.54 %

Age of people who have Drug Resistance when taking Azathioprine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 5.13 %
  • 20-29: 25.64 %
  • 30-39: 23.08 %
  • 40-49: 15.38 %
  • 50-59: 17.95 %
  • 60+: 12.82 %

Top conditions involved for these people *:

  • Pemphigus (15 people)
  • Crohn's Disease (6 people)
  • Autoimmune Hepatitis (6 people)
  • Heart Transplant (3 people)
  • Renal Transplant (2 people)

Top co-used drugs for these people *:

  • Prednisolone (21 people)
  • Mycophenolic Acid (14 people)
  • Cyclosporine (14 people)
  • Mycophenolate Mofetil (9 people)
  • Cyclophosphamide (9 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Drug resistance when taking Azathioprine?

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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