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Review: could Azithromycin cause Anaphylaxis?

Summary: Anaphylaxis could be caused by Azithromycin, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take Ibuprofen, and have Pneumonia.

We study 10,896 people who have side effects while taking Azithromycin from FDA and social media. Among them, 73 have Anaphylaxis. Find out below who they are, when they have Anaphylaxis and more.

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Azithromycin

Azithromycin (latest outcomes from 12,294 users) has active ingredients of azithromycin. It is often used in sinusitis, infection. Commonly reported side effects of Azithromycin include pain exacerbated, pain, nausea aggravated, nausea, stress and anxiety.

Anaphylaxis

Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death) (latest reports from 107,166 patients) has been reported by people with multiple sclerosis, asthma, high blood pressure, premedication, pain.

On Apr, 6, 2014: 10,759 people reported to have side effects when taking Azithromycin. Among them, 73 people (0.68%) have Anaphylaxis. They amount to 0.07% of all the 106,883 people who have Anaphylaxis on eHealthMe.

Trend of Anaphylaxis in Azithromycin reports

Time on Azithromycin when people have Anaphylaxis * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Anaphylaxis100.00%0.00%0.00%0.00%0.00%0.00%0.00%

Gender of people who have Anaphylaxis when taking Azithromycin * :

FemaleMale
Anaphylaxis53.33%46.67%

Age of people who have Anaphylaxis when taking Azithromycin * :

0-12-910-1920-2930-3940-4950-5960+
Anaphylaxis0.00%4.84%4.84%14.52%11.29%22.58%14.52%27.42%

Severity of Anaphylaxis when taking Azithromycin ** :

n/a

How people recovered from Anaphylaxis ** :

n/a

Top conditions involved for these people * :

  1. Pneumonia (8 people, 10.96%)
  2. Hiv infection (7 people, 9.59%)
  3. Bronchitis (6 people, 8.22%)
  4. Tuberculosis (4 people, 5.48%)
  5. Arthritis (4 people, 5.48%)

Top co-used drugs for these people * :

  1. Ibuprofen (9 people, 12.33%)
  2. Albuterol (6 people, 8.22%)
  3. Isoniazid (5 people, 6.85%)
  4. Kaletra (5 people, 6.85%)
  5. Prednisone (5 people, 6.85%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Azithromycin, Anaphylaxis

You can also:

On eHealthMe, Azithromycin (azithromycin) is often used for sinusitis. Find out below the conditions Azithromycin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Azithromycin used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (2 weeks ago):

  • one dose of Azithromycin taken and my eyes felt weird; stiff, gritty, gone by the next day. Haven't taken any more since

    Reply

  • From this study (2 weeks ago):

  • I went to the emergency room because I noticed that the bottom of my face was swollen on the right side next to my chin. I was not in any pain, but thought it was strange and because I had never noticed anything like that before. The doctor was not sure what was wrong with me, said he thought it was a blocked salivary gland, and prescribed me ciproflaxin and clyndamyacin. I have been perscribed both medications at seperate times no more than 2 years before this happened without having any marked adverse response. I filled the perscriptions immediately after leaving the hospital and took them once I arrived at home. Shortly, (10-40 minutes - less than one hour) after I took both pills together as instructed at the hospital, I started having extreme stomach pain and cramps, so extreme that i was writhing in pain and said that i felt like i had been poisoned. I lay down to try to go to bed becasue i was in so much pain, and woke up 1-2 hours later, itching more severely than ever before everywhere on my body including my scalp, the palms of my hands, and the soles of my feet. When I turned on the light I saw that my entire body was completely red and covered with hives, then my face started swelling up, my lips, cheeks, eyes, it seemed like my entire head was swelling. I'm not certain if my tongue was swelling or if i started having a panic attack that made it seem difficult to breathe (i have had panic attacks before). went to emergency room was treated with epi-pen, pepcid, benadryl, among other meds i cannot recall. nothing like this has ever occured before or since.

    Reply

  • From this study (3 weeks ago):

  • After 7 weeks on azithromycin 500mg IV daily, with pre-existing tinnitus, developed sudden hearing loss left ear. IV zithromax discontinued 3 days later. 4 days after Azithromycin discontinued, experienced vertigo; diagnosed with Meniere's disease.

    Reply

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