Azithromycin and Clostridium difficile colitis - from FDA reports


Summary

Clostridium difficile colitis is found among people who take Azithromycin, especially for people who are male, 60+ old , have been taking the drug for < 1 month, also take medication Omeprazole, and have Pseudomonas infection. This review analyzes which people have Clostridium difficile colitis with Azithromycin. It is created by eHealthMe based on reports of 17,267 people who have side effects when taking Azithromycin from FDA, and is updated regularly.

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On May, 16, 2017

17,267 people reported to have side effects when taking Azithromycin.
Among them, 81 people (0.47%) have Clostridium Difficile Colitis


Number of reports submitted per year:

Could Azithromycin cause Clostridium difficile colitis?

Time on Azithromycin when people have Clostridium Difficile Colitis *:

  • < 1 month: 86.36 %
  • 1 - 6 months: 4.55 %
  • 6 - 12 months: 4.55 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 4.55 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Clostridium Difficile Colitis when taking Azithromycin *:

  • female: 29.49 %
  • male: 70.51 %

Age of people who have Clostridium Difficile Colitis when taking Azithromycin *:

  • 0-1: 2.86 %
  • 2-9: 2.86 %
  • 10-19: 1.43 %
  • 20-29: 15.71 %
  • 30-39: 28.57 %
  • 40-49: 5.71 %
  • 50-59: 12.86 %
  • 60+: 30.0 %

Top conditions involved for these people *:

  • Pseudomonas Infection (18 people, 22.22%)
  • Gastroesophageal Reflux Disease (15 people, 18.52%)
  • Mycobacterium Abscessus Infection (13 people, 16.05%)
  • Preventive Health Care (6 people, 7.41%)
  • High Blood Pressure (6 people, 7.41%)

Top co-used drugs for these people *:

  • Omeprazole (30 people, 37.04%)
  • Meropenem (25 people, 30.86%)
  • Clarithromycin (19 people, 23.46%)
  • Metronidazole (15 people, 18.52%)
  • Tobi (12 people, 14.81%)

Top other side effects for these people *:

  • Dehydration (35 people, 43.21%)
  • Hypotension (29 people, 35.80%)
  • Arrhythmias (29 people, 35.80%)
  • Pseudomembranous Colitis (28 people, 34.57%)
  • Fever (25 people, 30.86%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Clostridium difficile colitis when taking Azithromycin?

Azithromycin

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What would happen?

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