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Review: could Azithromycin cause Clostridium difficile colitis?

Summary: Clostridium difficile colitis is found among people who take Azithromycin, especially for people who are male, 30-39 old, have been taking the drug for < 1 month, also take medication Omeprazole, and have Pseudomonas infection.

We study 10,946 people who have side effects while taking Azithromycin from FDA and social media. Among them, 57 have Clostridium difficile colitis. Find out below who they are, when they have Clostridium difficile colitis and more.

You are not alone: join a mobile support group for people who take Azithromycin and have Clostridium difficile colitis >>>

 

 

 

 

Azithromycin

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. (latest outcomes from 12,354 Azithromycin users)

Clostridium difficile colitis

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection) has been reported by people with high blood pressure, osteoporosis, multiple myeloma, pain, multiple sclerosis. (latest reports from 3,639 Clostridium difficile colitis patients)

On Feb, 13, 2015: 10,946 people reported to have side effects when taking Azithromycin. Among them, 57 people (0.52%) have Clostridium Difficile Colitis.

Trend of Clostridium difficile colitis in Azithromycin reports

Time on Azithromycin when people have Clostridium difficile colitis * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Clostridium difficile colitis91.67%0.00%8.33%0.00%0.00%0.00%0.00%

Gender of people who have Clostridium difficile colitis when taking Azithromycin * :

FemaleMale
Clostridium difficile colitis19.30%80.70%

Age of people who have Clostridium difficile colitis when taking Azithromycin * :

0-12-910-1920-2930-3940-4950-5960+
Clostridium difficile colitis0.00%1.92%0.00%19.23%36.54%5.77%7.69%28.85%

Severity of Clostridium difficile colitis when taking Azithromycin ** :

n/a

How people recovered from Clostridium difficile colitis ** :

n/a

Top conditions involved for these people * :

  1. Pseudomonas infection (18 people, 31.58%)
  2. Gastrooesophageal reflux disease (15 people, 26.32%)
  3. Mycobacterium abscessus infection (13 people, 22.81%)
  4. Prophylaxis (8 people, 14.04%)
  5. Pneumonia (8 people, 14.04%)

Top co-used drugs for these people * :

  1. Omeprazole (30 people, 52.63%)
  2. Meropenem (26 people, 45.61%)
  3. Ciprofloxacin (23 people, 40.35%)
  4. Clarithromycin (18 people, 31.58%)
  5. Minocycline hcl (15 people, 26.32%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of azithromycin and clostridium difficile colitis on

Do you have Clostridium Difficile Colitis while taking Azithromycin?

You are not alone! Join a mobile support group:
- support group for people who take Azithromycin and have Clostridium Difficile Colitis
- support group for people who take Azithromycin
- support group for people who have Clostridium Difficile Colitis

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More questions for: Azithromycin, Clostridium difficile colitis

You may be interested at these reviews (Write a review):

  • Cdifficile treatment
    I had drug (cipro) induced cdifficile for three and a half years and was hospitalized 3 times and went through absolute hell until my Dr. finally agreed to do a fecal transplant. Even then the first transfer done via a lower bowel infusion didnt work. Two weeks after the first one he did a full colonoscopy transfer going up as high as my appendix and that one worked immediatly and I have had no furthur bowel problems, no diarrea at all and its' now been well over a year. I took every type of cdiff drug imaginable prior to that. I had to stay on Vancomyicin all the time or I would be spending all my time going back and forth to the john 20 or 30 times a day. I was so ill that I could bearly keep my head up. I couldnt eat without an urgent bathroom trip. I had to wear Depends all the time, my skin was raw and sore from constant wiping. I was given Tinture of Morphine to slow me down. That helped some. My veins collapsed from all the test shots and from the many pints of saline to keep me hydrated. My heart stopped from a lowering of my potassium level and I had to get a pacemaker to control my heart rate. I spent a fortune on the drugs,some costing as much as $1200.00 a month, more than I make working and working was rough. I would have to go to the restroom so often and I work outside where there were frequently no facilities. I would have to bring a complete change of clothes and a disinfecting kit with me to cleanup the restroom. I washed my hands raw. You cant leave that for someone else or they might get sick too as it is highly infectious. Hospitals are not that meticulous either. I once had to go to a Long Island Hospital that failed the precautions test miserably. They assigned me to a room with another patient whose family wanted to eat their meals in our shared room and then use the bathroom. I pitched a fit on them and told them no way were they going to eat in that room or use the bathroom. I can't imagine what that hospital was thinking. Anyway you get the idea....3 years of expensive treatment and all I needed was some healthy donor poop and someone willing to mix it up in a blender and put it in syringe and put it up the wassoo and I was done. Dont let them give you all the expensive treatment if you have a resistant case of cdiff, insist on the fecal transplant right off, you will be very glad you did. The donor should be someone in your family, preferably someone young with lots of good flora for digestion. Someone without other gut problems...they need to test them too. Bring it in the afternoon before and Bingo,you will be back on track the next day. I am open to answer questions or be tested orhelp with anything else you might want to know, just ask me.
  • Adverse effect of azithromycin
    patients immunesystem showed very bad response to azithromycin adminstered as 1000mg per day 3 days and then 1000mg once a week for 6 weeks -

    a previously chronic sinuitis flared up as did a over 30 year old infection in a broken toe -

    dicillin was given for 10 days 3000mg per day / 1000mg 3 times daily - with good effect -

    the patents journal shows evidence of similar occurence a decade ago when taking Klacid uno also of the macrolid family -
    it appears macrolids can have severe adverse effect on some patients immunesystem
  • Azithromycin side effect skin hyperpigmentation (1 response)
    My 6-year-old daughter took 5-day course azithromycin 3 times in 5 months for sinus infections. Do not recall exactly when hyperpigmentation began appearing all over front of neck, but definitely by the 3rd month after initial dose, with subsequent darkening upon taking two more prescriptions within the 5 months. Disappeared after treating 1x/day for 2 days with aloe vera gel directly from the plant rubbed all over darkened areas; all hyperpigmentation scrubbed off with oatmeal/honey scrub on 3rd day. No recurrence until about 6 months later with minimal to moderate autumn sun exposure, recurrence all over front of neck again, even though never took azithromycin beyond the 3 prescriptions. About two weeks after this started, now entire side of one ankle is hyperpigmented. Very concerned how much more it will spread. Will up aloe vera gel application frequency in hopes to get rid of it. Stay away from this drug! It is definitely too new of a drug to be prescribing for kids!
  • Clindamycin induced clostridium difficile colitis (1 response)
    Dentist prescribed 10 day prescription of Clindamycin for tooth ache, where a week after completing it, a near fatal CDiff infection developed. Renal failure and 3 weeks in hospital followed by 2 months of rehab. No probiotics were taken with the antibiotic. Vancomycin and Flagyl cured the CDiff infection.



    Advice: DO NOT TAKE THIS DRUG, IT IS TOO DESTRUCTIVE!

More reviews for: Azithromycin, Clostridium difficile colitis

Comments from related studies:

  • From this study (11 hours ago):

  • I have had C-diff since 9/3 2014. I am on my 5th reoccurrence of it, and I took flagyl twice and vancomyacin with the secondary medication. no relief. Ended in the hospital with dehydration, lack of potassium and felt horrible.
    My moods, have been up and down, since I just came down with a bladder infection two weeks before my fecal transplant and it took them a week to give me the antibiotics. They gave me bacteria, and all of the sudden on the 4th day my knees hurt, my upper thighs. I do wonder what is wrong. I have always been a very compliant do not complain patient but gosh, I feel like I am going to die from .
    I do not know how I can continue to work?

    Reply

  • From this study (11 hours ago):

  • I have had C-diff since 9/3 2014. I am on my 5th reoccurrence of it, and I took flagyl twice and vancomyacin with the secondary medication. no relief. Ended in the hospital with dehydration, lack of potassium and felt horrible.
    My moods, have been up and down, since I just came down with a bladder infection two weeks before my fecal transplant and it took them a week to give me the antibiotics. They gave me bacteria, and all of the sudden on the 4th day my knees hurt, my upper thighs. I do wonder what is wrong. I have always been a very compliant do not complain patient but gosh, I feel like I am going to die.
    I do not know how I can continue to work?

    Reply

  • From this study (1 week ago):

  • Bleeding for over a week with clots heavy abdominal cramps first two days after taking the drug

    Reply

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