Review: could Baclofen cause Muscle Weakness?


Muscle weakness is found among people who take Baclofen, especially for people who are female, 50-59 old , have been taking the drug for < 1 month, also take medication Avonex, and have Multiple sclerosis . We study 25,569 people who have side effects while taking Baclofen from FDA and social media. Among them, 2,141 have Muscle weakness. Find out below who they are, when they have Muscle weakness and more.

You are not alone

Join a support group for people who take Baclofen and have Muscle weakness >>>

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Baclofen has active ingredients of baclofen. It is often used in muscle spasticity. (latest outcomes from Baclofen 26,118 users)

Muscle Weakness

Muscle weakness (a lack of muscle strength) has been reported by people with breathing difficulty, rashes, diarrhea, insomnia, fatigue (latest reports from 199,501 Muscle weakness patients).

On Aug, 21, 2016

25,569 people reported to have side effects when taking Baclofen.
Among them, 2,141 people (8.37%) have Muscle Weakness

Number of reports submitted per year:

Could Baclofen cause Muscle weakness?

Time on Baclofen when people have Muscle Weakness *:

  • < 1 month: 33.96 %
  • 1 - 6 months: 13.21 %
  • 6 - 12 months: 3.77 %
  • 1 - 2 years: 28.3 %
  • 2 - 5 years: 3.77 %
  • 5 - 10 years: 5.66 %
  • 10+ years: 11.32 %

Gender of people who have Muscle Weakness when taking Baclofen *:

  • female: 67.83 %
  • male: 32.17 %

Age of people who have Muscle Weakness when taking Baclofen *:

  • 0-1: 0.0 %
  • 2-9: 1.37 %
  • 10-19: 0.63 %
  • 20-29: 3.59 %
  • 30-39: 12.62 %
  • 40-49: 27.51 %
  • 50-59: 28.09 %
  • 60+: 26.14 %

Severity if Muscle Weakness when taking Baclofen **:

  • least: 0.0 %
  • moderate: 43.75 %
  • severe: 50.0 %
  • most severe: 6.25 %

How people recovered from Muscle Weakness **:

  • while on drug: 0.0 %
  • after off the drug: 15.38 %
  • not yet: 84.62 %

Top conditions involved for these people *:

  • Multiple Sclerosis (901 people)
  • Pain (185 people)
  • Muscle Spasticity (183 people)
  • Muscle Spasms (159 people)
  • Gait Disturbance (114 people)

Top co-used drugs for these people *:

  • Avonex (335 people)
  • Neurontin (299 people)
  • Gabapentin (255 people)
  • Tysabri (241 people)
  • Rebif (203 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Muscle weakness when taking Baclofen?

Browse all side effects of Baclofen

a b c d e f g h i j k l m n o p q r s t u v w x y z

Drugs that are associated with Muscle weakness

Muscle weakness

Could your condition cause Muscle weakness

Muscle weakness

Can you answer these questions?

More questions for: Baclofen, Muscle weakness

You may be interested in these reviews

More reviews for: Baclofen, Muscle weakness

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.