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Related topic: Benadryl, Anaphylaxis

Review: could Benadryl cause Anaphylaxis?

Summary: Anaphylaxis could be caused by Benadryl, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take Decadron, and have Prophylaxis.

We study 26,326 people who have side effects while taking Benadryl from FDA and social media. Among them, 529 have Anaphylaxis. Find out below who they are, when they have Anaphylaxis and more.

How are my drugs for patients like me? On eHealthMe, you can research 300 million drug outcomes from FDA and social media. All studies are personalized to gender and age. Start now, it's anonymous, simple & free >>>

Benadryl

Benadryl (latest outcomes from 29,278 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergen.

Anaphylaxis

Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death) (latest reports from 107,197 patients) has been reported by people with multiple sclerosis, asthma, high blood pressure, premedication, pain.

On Apr, 11, 2014: 26,199 people reported to have side effects when taking Benadryl. Among them, 529 people (2.02%) have Anaphylaxis. They amount to 0.49% of all the 106,968 people who have Anaphylaxis on eHealthMe.

Trend of Anaphylaxis in Benadryl reports

Time on Benadryl when people have Anaphylaxis * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Anaphylaxis92.63%3.16%0.00%0.00%0.00%4.21%0.00%

Gender of people who have Anaphylaxis when taking Benadryl * :

FemaleMale
Anaphylaxis65.59%34.41%

Age of people who have Anaphylaxis when taking Benadryl * :

0-12-910-1920-2930-3940-4950-5960+
Anaphylaxis1.84%6.56%3.89%4.10%11.07%12.30%20.08%40.16%

Severity of Anaphylaxis when taking Benadryl ** :

leastmoderateseveremost severe
Anaphylaxis0.00%33.33%0.00%66.67%

How people recovered from Anaphylaxis ** :

while on the drugafter off the drugnot yet
Anaphylaxis100.00%0.00%0.00%

Top conditions involved for these people * :

  1. Prophylaxis (32 people, 6.05%)
  2. Urticaria (28 people, 5.29%)
  3. Asthma (28 people, 5.29%)
  4. Pruritus (19 people, 3.59%)
  5. Crohn's disease (18 people, 3.40%)

Top co-used drugs for these people * :

  1. Decadron (108 people, 20.42%)
  2. Solu-medrol (72 people, 13.61%)
  3. Zantac (66 people, 12.48%)
  4. Erbitux (57 people, 10.78%)
  5. Aspirin (57 people, 10.78%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

On eHealthMe, Benadryl (diphenhydramine hydrochloride) is often used for allergen. Find out below the conditions Benadryl is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Benadryl used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (3 years ago):

  • I have been on Dilantin for 6 years for a stage 4 malignant brain tumor that was successfully removed. In the last six months I have had hives, swelling, anaphylaxis, ER visits, blood tests for food allergies... etc. etc. I am taking Doxepin, Singulair, Prednisone, Ranitidine, and clarinex - all prescribed by my allergist. However, I still have awful hives covering my body.

    Reply

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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