Review: could Benadryl cause Aortic Stenosis?


Aortic stenosis is found among people who take Benadryl, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Zyrtec, and have Depression . We study 38,823 people who have side effects while taking Benadryl from FDA and social media. Among them, 50 have Aortic stenosis. Find out below who they are, when they have Aortic stenosis and more.

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Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (latest outcomes from Benadryl 44,667 users)

Aortic Stenosis

Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta) has been reported by people with high blood pressure, diabetes, depression, osteoporosis, rheumatoid arthritis (latest reports from 4,651 Aortic stenosis patients).

On Nov, 09, 2016

38,823 people reported to have side effects when taking Benadryl.
Among them, 50 people (0.13%) have Aortic Stenosis

Number of reports submitted per year:

Could Benadryl cause Aortic stenosis?

Time on Benadryl when people have Aortic Stenosis *:

  • < 1 month: 80 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 20 %
  • 10+ years: 0.0 %

Gender of people who have Aortic Stenosis when taking Benadryl *:

  • female: 77.55 %
  • male: 22.45 %

Age of people who have Aortic Stenosis when taking Benadryl *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 2.94 %
  • 20-29: 2.94 %
  • 30-39: 0.0 %
  • 40-49: 5.88 %
  • 50-59: 11.76 %
  • 60+: 70.59 %

Severity of Aortic Stenosis **:

  • least: 0.0 %
  • moderate: 100 %
  • severe: 0.0 %
  • most severe: 0.0 %

Top co-used drugs for these people *:

  • Zyrtec (21 people, 42.00%)
  • Tylenol (15 people, 30.00%)
  • Albuterol (15 people, 30.00%)
  • Lantus (12 people, 24.00%)
  • Aspirin (12 people, 24.00%)

Forecasts by (We will alert you to new symptoms or undetected conditions when you take Benadryl, learn more)


* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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