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Review: could Benadryl cause Arrhythmia?

Summary: Arrhythmia could be caused by Benadryl, especially for people who are male, 60+ old, have been taking the drug for < 1 month, also take Aspirin, and have Hypertension.

We study 26,199 people who have side effects while taking Benadryl from FDA and social media. Among them, 289 have Arrhythmia. Find out below who they are, when they have Arrhythmia and more.

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Benadryl

Benadryl (latest outcomes from 29,278 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergen.

Arrhythmia

Arrhythmia (irregular heartbeat) (latest reports from 282,017 patients) has been reported by people with high blood pressure, pain, osteoporosis, diabetes, depression.

On Apr, 13, 2014: 26,199 people reported to have side effects when taking Benadryl. Among them, 305 people (1.16%) have Arrhythmia. They amount to 0.11% of all the 281,579 people who have Arrhythmia on eHealthMe.

Trend of Arrhythmia in Benadryl reports

Time on Benadryl when people have Arrhythmia * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Arrhythmia90.91%0.00%0.00%0.00%0.00%0.00%9.09%

Gender of people who have Arrhythmia when taking Benadryl * :

FemaleMale
Arrhythmia49.39%50.61%

Age of people who have Arrhythmia when taking Benadryl * :

0-12-910-1920-2930-3940-4950-5960+
Arrhythmia1.55%1.94%6.20%3.49%3.88%7.75%18.99%56.20%

Severity of Arrhythmia when taking Benadryl ** :

n/a

How people recovered from Arrhythmia ** :

n/a

Top conditions involved for these people * :

  1. Hypertension (38 people, 12.46%)
  2. Multiple myeloma (33 people, 10.82%)
  3. Blood cholesterol (30 people, 9.84%)
  4. Depression (28 people, 9.18%)
  5. Arthralgia (26 people, 8.52%)

Top co-used drugs for these people * :

  1. Aspirin (95 people, 31.15%)
  2. Lasix (92 people, 30.16%)
  3. Lipitor (66 people, 21.64%)
  4. Zofran (64 people, 20.98%)
  5. Protonix (64 people, 20.98%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Benadryl, Arrhythmia

You can also:

On eHealthMe, Benadryl (diphenhydramine hydrochloride) is often used for allergen. Find out below the conditions Benadryl is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Benadryl used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (2 years ago):

  • Roger Gaby on Jul, 12, 2012:

    Iam a 69 year-old male with a history of Mitral valve replacement and triple bypass (2008). The valve was replaced due to prolapse and atrial arrhythmia. I have been symptom free for the past 4 years (slight arrhythmia) when, after taking Tylenol Pm for sleep aid several weeks ago , I developed a tachyarrhythmia (HR over 150 BPM). After 4 days duration I saw my cardiologist who put me on a blood thinner and scheduled a visit to an EP for cardioversion. 2days after ceasing the Tylenol Pm I self cardioverted to sinus rhythm (mild arrhythmia still present) . I am a health care professional,retired Director of Regulatory Affairs at GSK and feel that I can state that the diphendramine was causal in the episode.

    Reply

Can you answer these questions (what is this?):

More questions for: Benadryl, Arrhythmia

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  • Dilantin and interactions
    I've taken Dilantin for over 40 years..seizure free for over 30 years..became hypothyroid 10 years ago..B12 deficient approximately 3 years ago and have had a benign arrhythmia for over 30 years. I take magnesium because it seems to hep the arrhythmia and vitamin d because mine is low normal.

More reviews for: Benadryl, Arrhythmia

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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